Search results for "Expression"
showing 10 items of 5168 documents
Nucleotide sequence of an adult-specific cuticular protein gene from the beetle Tenebrio molitor: effects of 20-hydroxyecdysone on mRNA accumulation.
1993
0962-1075 (Print) Journal Article Research Support, Non-U.S. Gov't; The accumulation of transcripts from two adult-specific cuticular genes (ACP-20 and ACP-22) is shown to be modified after addition of exogenous 20-hydroxyecdysone. In the continuous presence of high levels of the hormone, the expression of ACP-20 gene is significantly weaker than that of untreated controls, while ACP-22 expression is 2.5-fold increased. During active synthesis of the ACP messages, a 0.5 microg 20-hydroxyecdysone injection causes a rapid 2-fold increase in ACP-22 mRNA and is not able to repress ACP-20 mRNA accumulation. We conclude that these genes whose transcripts appear in an almost coordinated manner in …
Correlation between cell line chemosensitivity and protein expression pattern as new approach for the design of targeted anticancer small molecules
2022
BACKGROUND AND RATIONALE: Over the past few decades, several databases with a significant amount of biological data related to cancer cells and anticancer agents (e.g.: National Cancer Institute database, NCI; Cancer Cell Line Encyclopedia, CCLE; Genomic and Drug Sensitivity in Cancer portal, GDSC) have been developed. The huge amount of heterogeneous biological data extractable from these databanks (among all, drug response and protein expression) provides a real foundation for predictive cancer chemogenomics, which aims to investigate the relationships between genomic traits and the response of cancer cells to drug treatment with the aim to identify novel therapeutic molecules and targets…
Expression Therapies Through Installation
2017
La instalación como vía de expresión híbrida en la que se contempla la utilización del espacio con un sentido de intervención creativa, - arquitectura, pintura, escultura, fotografía, vídeo, performance, danza, dramatización y música- entre otras disciplinas implicadas, proporciona al campo de la terapia un universo sensorial y proposicional que puede tomarse como base conceptual en el proceso terapéutico mediante las artes.Partiendo del análisis sobre aspectos conceptuales y artistas de referencia de la instalación y tomando en consideración aspectos pertenecientes a terapias de expresión artística, se plantean sesiones arteterapéuticas fundamentadas en el uso de la instalación. The hybrid…
Performing arts and mediation technology in the period of lockdown
2021
Advancements in digital technologies have become novel ways to enrich communication, expression, and transmission of arts knowledge. Technology is increasingly implemented in the performance space, as a source of inspiration for artists. Especially in this period of lockdown, mediation technology has turned out to be an essential tool for different aspects of social life, as in performing arts. With venues, schools and artistic activities closed, performers, students and spectators have been obliged to keep connecting in remote conditions. This article wants to retrace the aesthetic impact of mediation technology in performing arts during this period of lockdown by focusing on the aspects t…
De la performance musicale dans la Guyane traditionnelle : expression cognitive singulière d?une musique-verbe
2021
Guianese culture and traditional music, here evoked, are various. It is more a transcultural process that, along centuries, gave an original result born in the Americas, in Guiana in this case. It is a form of refoundation, of recreation of cultures and new human beings generally called Creoles. The musical performance, that I study here, is the echo of social and cultural space of this reformulation of thought, life, and conception of the world. It is, as well, a mean of transposition and transformation of the values issued of diverse sources and categories. It is in no way a second-rate cultural practice, as it is the place where were born philosophies and actions for common life as well …
A Conceptual Restructuring of Spatial Motion Expressions in Chinese L2
2018
This paper focuses on the patterns in the encoding of spatial motion events that play a major role in the acquisition of these type of expressions. The goal is to single out the semantic contribution of the linguistic items which surface in Chinese locative constructions. In this way, we intend to provide learners with an account of the spatial representation encoded in the Chinese language. In fact, Chinese grammar is often perceived as idiosyncratic, thus generating a frustration that turns into learned helplessness (Maier and Seligman, 1976). We will analyze Talmy (2000a,b) framework under the light of investigations such as Landau and Jackendoff (1993), Svenonius (2004, 2006, 2007), and…
The increase in maternal expression of axin1 and axin2 contribute to the zebrafish mutant ichabod ventralized phenotype.
2014
β-Catenin is a central effector of the Wnt pathway and one of the players in Ca(+)-dependent cell-cell adhesion. While many wnts are present and expressed in vertebrates, only one β-catenin exists in the majority of the organisms. One intriguing exception is zebrafish that carries two genes for β-catenin. The maternal recessive mutation ichabod presents very low levels of β-catenin2 that in turn affects dorsal axis formation, suggesting that β-catenin1 is incapable to compensate for β-catenin2 loss and raising the question of whether these two β-catenins may have differential roles during early axis specification. Here we identify a specific antibody that can discriminate selectively for β-…
Interacción insecto-baculovirus. Aplicaciones en la mejora de baculovirus como vector para la expresión heteróloga de proteínas.
2018
Los baculovirus forman un amplio grupo de virus patógenos de insectos que se caracterizan por su elevada especificidad. Su principal aplicación es su uso como agente bioinsecticida frente a diferentes plagas agrícolas, aunque algunas de sus características han permitido el desarrollo de tecnologías que permiten usar los baculovirus como vectores para la expresión heteróloga de proteínas, así como vectores para su uso en terapia génica. El sistema de expresión basado en baculovirus, conocido como BEVS (Baculovirus Expression Vector System), fue desarrollado en los años 80 y desde entonces ha permitido la expresión de gran diversidad de proteínas recombinantes en cultivos celulares de insecto…
Il negazionismo: fenomenologia e profili normativi
2022
A (1->3)-beta-D-glucan recognition protein from the sponge Suberites domuncula. Mediated activation of fibrinogen-like protein and epidermal growth f…
2004
Sponges (phylum Porifera) live in a symbiotic relationship with microorganisms, primarily bacteria. Until now, molecular proof for the capacity of sponges to recognize fungi in the surrounding aqueous milieu has not been available. Here we demonstrate, for the demosponge Suberites domuncula (Porifera, Demospongiae, Hadromerida), a cell surface receptor that recognizes (1--3)-beta-D-glucans, e.g. curdlan or laminarin. This receptor, the (1--3)-beta-D-glucan-binding protein, was identified and its cDNA analysed. The gene coding for the 45 kDa protein was found to be upregulated in tissue after incubation with carbohydrate. Simultaneously with the increased expression of this gene, two further…