Search results for "External"
showing 10 items of 601 documents
Comparing DNA sequence collections by direct comparison of compressed text indexes
2012
Popular sequence alignment tools such as BWA convert a reference genome to an indexing data structure based on the Burrows-Wheeler Transform (BWT), from which matches to individual query sequences can be rapidly determined. However the utility of also indexing the query sequences themselves remains relatively unexplored. Here we show that an all-against-all comparison of two sequence collections can be computed from the BWT of each collection with the BWTs held entirely in external memory, i.e. on disk and not in RAM. As an application of this technique, we show that BWTs of transcriptomic and genomic reads can be compared to obtain reference-free predictions of splice junctions that have h…
William J. Morgan’s ‘conventionalist internalism’ approach. Furthering internalism? A critical hermeneutical response
2014
Several authors, such as William J. Morgan, John S. Russell and R. Scott Kretchmar, have claimed that the limits between the diverse normative theories of sport need to be revisited. Most of these works are philosophically grounded in Anglo-American philosophical approaches. For instance, William J. Morgan’s proposal is mainly based on Richard Rorty’s philosophy. But he also discusses with some European philosophers like Jurgen Habermas. However, Habermas’ central ideas are rejected by Morgan. The purpose of this paper is to analyse Morgan’s rejection of Habermas’ thought and show that a more appropriate normative of sport that explains better our current sporting world can be achieved by d…
Reliability and Validity of Family Affluence Scale (FAS II) among Adolescents in Beijing, China
2011
This study comprises two sub-studies. Study I assessed the test-retest reliability of Family Affluence Scale (FAS II) items among 95 students aged 11 and 15 years old in Beijing. Study II investigated the completion rate of traditional indicators (parents’ educational level, perceived family wealth, resident area, and school location) measuring socioeconomic status (SES) compared with FAS II, and examined the internal reliability, external and construct validity of the FAS II items in a population of 5876 schoolchildren aged 11, 13 and 15 years old in Beijing. Our study found that the FAS II items have high completion rates (> 99%) which are better than other SES indicators. Analyses of rel…
Psychometric Evaluation of Nursing Professionals Involved in Palliative Care
2017
12 páginas Objetivos: Validar las escalas de Bienestar Psicológico de Ryff en enfermería y relacionarlas con variables clave en calidad de vida laboral. Materiales y método: participaron por encuesta electrónica autoadministrada anónima 433 profesionales, 33.1% profesionales de enfermería (n=123) en quienes nos centramos. Además de sociodemográficos, se recogió información sobre bienestar psicológico, atención consciente, afrontamiento de la muerte y calidad de vida. La validez de constructo fue evaluada con análisis factorial confirmatorio. Se estimó fiabilidad y se recogieron evidencias de validez externa. Resultados: El modelo mostró ajuste adecuado: c2(362) = 438.59 (p = .01), CFI = .98…
The Origins of Social Ventures
2021
This chapter addresses the social venture as a form of organization that has a role in the current society. In an economy based on markets, the intervention of multiple actors by itself—like governments, social movements, charity, and social ventures—cannot ensure the mechanisms necessary to the proper working of the system. In this way, markets present a set of failures and externalities that government action tries to solve. However, government action is limited due to a set of circumstances. Social movements and charity emerge to overcome the government’s limitations. Social entrepreneurship, as the last organization analyzed in this chapter, arises when social movements and charities fa…
Preclinical report on allogeneic uterus transplantation in non-human primates
2013
Study question Is it possible to perform allogeneic uterus transplantation (UTx) with a donation from a live donor in a non-human primate species and what immunosuppression is needed to prevent rejection? Summary answer Allogeneic UTx in the baboon is a donor- and recipient-safe surgical procedure; immunosuppression with induction therapy and a triple protocol should be used. What is known already UTx may become a treatment for absolute uterine factor infertility. Autologous UTx models have been developed in non-human primates with reports on long-term survival of the uterine grafts. STUDY DESIGN, SIZEAND DURATION: This experimental study included 18 female baboons as uterus donors and 18 f…
Economic feasibility study for intensive and extensive wastewater treatment considering greenhouse gases emissions
2013
Economic feasibility assessments represent a key issue for selecting which wastewater treatment processes should be implemented. The few applications that exist focus on the positive economic value of externalities, overlooking the existence of negative externalities. However, wastewater treatment plants (WWTPs) consume a significant amount of energy, contributing to climate change. In this context, as a pioneering approach, greenhouse gas emissions (GHG) have been incorporated as a negative externality of wastewater treatment. Within this framework, this study aims to compare the economic feasibility of five technologies, both intensive and extensive, for small communities. The results sho…
Influence of maternal diet on the development of malformation of the external genitalia – Are we ready to make some recommendations?
2014
The influence of our environment on the development of malformation is well known and, again and again, discussed with great enthusiasm. For example, the supplementation of the diet with folic acid has been proven to prevent neural tube defects already in 1991 [1, 6]. However, despite this well–known fact, only 10.6% of women take folic acid at least four weeks before getting pregnant; although 60% know the increased risk. It was interesting to see, that there were no big differences between the social groups [7]. Some epidemiological studies suggest an increasing risk of disorders / malformation of the external genitalia in males. The influence of the hormonal environment, especially of an…
Innovation among SMEs in Finland: The impact of stakeholder engagement and firm-level characteristics
2021
PURPOSE: The aim of the paper is to analyse the importance of both internal capabilities (resources) and external information sources in implementing product, process, marketing and organizational innovations aiming to maximize firm competitive advantage and create value for stakeholders. Furthermore, in particular, we examine the role of public organizations, business networks, firm size, and the industry sector, in the emergence of different types of product, process, marketing, and organizational innovations. The research was based on the typology of innovation (product, process, marketing, and organizational) adopted by the OECD. METHODOLOGY: The paper is based on data from 389 SMEs loc…
THE REHABILITATION THROUGH EXTERNAL PRESTRESSING OF HISTORICAL REINFORCED CONCRETE BRIDGES WITH REDUCED PERFORMANCE: A CASE STUDY
2022
Many existing reinforced concrete bridges exhibit behaviour at the Service Limit State and the Ultimate Limit State which can be considered unsatisfactory with respect to the current provisions of Codes, but which are actually deficiencies deriving from obsolete calculation methods, structure age, material degradation, diffuse or localized corrosion and increased loads. Among these, cantilever bridges with half-joints may present a decrease in global safety coefficients for the most stressed current sections of the deck or in the local ones, that affect the performance of elements sensitive to degradation, such as Gerber saddles. In these cases, simple strengthening interventions through ex…