Search results for "Eye"

Immune-Mediated Desquamative Gingivitis and Optical Coherence Tomography Diagnostic Patterns: Clinical Implication from a Systematic Review

2021

Desquamative Gingivitis (DG) comprises heterogeneous clinical manifestations of numerous immune-mediated muco-cutaneous diseases. Optical Coherence Tomography (OCT) has been proposed as a valuable diagnostic support even if, to date, there are no standardized OCT-diagnostic patterns applicable to DGs. A systematic review was performed to detect existing data on in vivo OCT diagnostic patterns of the most common immune-mediated DGs (i.e., pemphigus vulgaris, mucous membrane pemphigoid and oral lichen planus). It has been found that OCT exhibits specific patterns that address the diagnosis of DG by pemphigus vulgaris (i.e., intraepithelial unilocular blister, reduced epithelial thickness, pre…

Anterior Capsule Opening Contraction and Late Intraocular Lens Dislocation after Cataract Surgery in Patients with Weak or Partially Absent Zonular S…

2021

Background and Objectives: To evaluate anterior capsule opening (ACO) contraction and late intraocular lens (IOL) dislocation after cataract surgery in patients with weak or partially absent zonular support and assess methods of reducing these complications. Materials and Methods: For this prospective study, we enlisted cataract surgery patients in our hospital with preoperative diagnoses of weak zonules. All patients received phacoemulsification surgery with implantation of a hydrophobic acrylic IOL and capsular tension ring (CTR). ACO reductions were measured for six months after enrolment. Data on late IOL dislocations were collected five years after enrolment of the last patient. Result…

Characterization of a new murine retinal cell line (MU-PH1) with glial, progenitor and photoreceptor characteristics

2013

Unlike fish and amphibians, mammals do not regenerate retinal neurons throughout life. However, neurogenic potential may be conserved in adult mammal retina and it is necessary to identify the factors that regulate retinal progenitor cells (RPC) proliferative capacity to scope their therapeutic potential. Müller cells can be progenitors for retinal neuronal cells and can play an essential role in the restoration of visual function after retinal injury. Some members of the Toll-like receptor (TLR) family, TLR2, TLR3 and TLR4, are related to progenitor cells proliferation. Müller cells are important in retinal regeneration and stable cell lines are useful for the study of retinal stem cell bi…

Reading ahead: Adult music students’ eye movements in temporally controlled performances of a children’s song

2014

In the present study, education majors minoring in music education ( n = 24) and music performance majors ( n =14) read and performed the original version and melodically altered versions of a simple melody in a given tempo. Eye movements during music reading and piano performances were recorded. Errorless trials were analyzed to explore the adjustments of visual processing in successful performances. The temporal length of the eye–hand span (time between gaze and the performed note) was typically around one second or less. A measure of gaze activity indicated that performers generally inspected two quarter-note areas between two metrical beat onsets. The performance majors operated with s…

2018

A music reader has to “look ahead” from the notes currently being played—this has usually been called the Eye-Hand Span. Given the restrictions on processing time due to tempo and meter, the Early Attraction Hypothesis suggests that sight readers are likely to locally increase the span of looking ahead in the face of complex upcoming symbols (or symbol relationships). We argue that such stimulus-driven effects on looking ahead are best studied using a measure of Eye-Time Span (ETS) which redefines looking ahead as the metrical distance between the position of a fixation in the score and another position that corresponds to the point of metrical time at fixation onset. In two experiments of…

The long history of rich fens supports persistence of plant and snail habitat specialists

2021

Increasing evidence for the effects of Holocene history on modern biotic communities suggests that current explanations of community patterns and conservation strategies require revisiting. Here we focused on Central European rich fens that are at high risk among mire habitats because of their relatively low environmental stability, and hence sensitivity to successional shifts. At each of 57 study sites, inventory of specialist species of bryophytes, vascular plants and land snails, measurements of local environmental conditions, area, and radiocarbon dating were conducted. We used Moran’s I spatial autocorrelation, multiple linear regression models, MDS, db-RDA, and null models to identify…

The Leber congenital amaurosis protein AIPL1 and EB proteins co-localize at the photoreceptor cilium.

2014

Purpose The aim of this study was to investigate the interaction and co-localization of novel interacting proteins with the Leber congenital amaurosis (LCA) associated protein aryl hydrocarbon receptor interacting protein-like 1 (AIPL1). Methods The CytoTrapXR yeast two-hybrid system was used to screen a bovine retinal cDNA library. A novel interaction between AIPL1 and members of the family of EB proteins was confirmed by directed yeast two-hybrid analysis and co-immunoprecipitation assays. The localization of AIPL1 and the EB proteins in cultured cells and in retinal cryosections was examined by immunofluorescence microscopy and cryo-immunogold electron microscopy. Results Yeast two-hybri…

Microaneurysms detection with the radon cliff operator in retinal fundus images

2010

ABSTRACT Diabetic Retinopathy (DR) is one of the leading causes of blindness in the industrialized world. Early detection is thekey in providing effective treatment. However, the current number of trained eye care specialists is inadequate to screenthe increasing number of diabetic patients. In recent years, automated and semi-automated systems to detect DR withcolor fundus images have been developedwith encouraging,but not fully satisfactory results. In this study we present theinitial results of a new techniquefor the detection and localization of microaneurysms,an early sign of DR. The algorithmis based on three steps: candidates selection, the actual microaneurysms detection and a Þnal …

A Survey on Microaneurysms Detection in Color Fundus Images

2020

Early Detection of Microaneurysms (MA) plays a vital role in preventing the blindness caused by diabetic retinopathy (DR). DR is preventable yet a serious diabetic problem. Treatment at an earlier stage reduces the risk of blindness. Microaneurysm is the first sign of DR found in fundus images while doing screening. Detection of MA is a challenging task mainly because of its size. MA appears as a tiny red spot ranging from 15µm to 60µm size. The most common way to detect the MA from a colour fundus image is by classification/segmentation through machine learning and deep learning approaches. The FROC-based performance evaluation shows that the existing methods can reach only up to 80% of se…

Detection of Fusarium Species in Clinical Specimens by Probe-Based Real-Time PCR

2019

The mold Fusarium is a ubiquitous fungus causing plant, animal and human infections. In humans, Fusarium spp. are the major cause of eye infections in patients wearing contact lenses or after local trauma. Systemic infections by Fusarium spp. mainly occur in immunosuppressed patients and can disseminate throughout the human body. Due to high levels of resistance to antifungals a fast identification of the causative agent is an urgent need. By using a probe-based real-time PCR assay specific for the genus Fusarium we analysed several different clinical specimens detecting Fusarium spp. commonly found in clinical samples in Germany. Also, a large collection of lung fluid samples of haematolog…