Search results for "FACTOR"
showing 10 items of 17757 documents
A systematic review of human behaviour in and around floodwater
2020
Abstract Flooding can have a major impact on people's safety and livelihood. Understanding people's flood-related behaviours may assist in the development of more effective strategies aimed at lessening the impact of floods including mortality and morbidity. This systematic review examined peer-reviewed literature published from January-1989 to April-2019 on human behaviour in and around floodwater to identify behaviour patterns as well as protective and risk factors. We extracted three main themes from a thematic analysis of included studies (N = 54): activities and risk-taking behaviours (n = 24); loss reduction, knowledge, and warnings (n = 37); and diet and hygiene (n = 4). This review …
Cognitive biases in humanitarian sensemaking and decision-making lessons from field research
2016
Time and again, humanitarian decision-makers are confronted with stress and pressure, distorted, lacking and uncertain information, and thus they are working in conditions that are known to introduce or enforce biases. Decision analysis has been designed to overcome such biases, and a network of “digital responders” organized over the Internet has set out to improve judgments by providing better information. However, without any structured support to determine objectives, goals and preferences and detached from the context of operational decision-makers, remote analysts may face the very biases they are trying to help overcome. This article sets out to identify biases that matter for humani…
A risk assessment proposal for underground cavities in Hard Soils-Soft Rocks
2018
Abstract Underground calcarenite quarries in Marsala (Sicily) have been involved in a number of collapses that have, seriously damaged numerous buildings. The stability conditions were therefore examined in order to assess risk conditions within the historical centre of the town and the surrounding areas, which are subject to urban expansion. Starting with an extensive collection of historical information, the research was carried out through surveys of the cavities, systematic sampling of material, petrographic analysis and geotechnical testing. The results of laboratory tests and in situ investigations provided a geotechnical characterization of both the intact material and the rock mass.…
Local expert experiences and perceptions of environmentally induced migration from Bangladesh to India
2017
This study investigates local expert perceptions of the role of environmental factors, especially in terms of contemporary climate change, in population movements from Bangladesh to India. The aim is to delve into locally held understandings of the phenomenon and to gain a better understanding of these migration processes, which are actively intertwined with local experiences. Both Indian and Bangladeshi experts were interviewed using semi-structured, in-depth interviews in order to explore insights from locally held perceptions and understandings of contextual factors. In total, 10 Bangladeshi and 15 Indian experts were interviewed, covering different disciplines, sectors, regions and job …
New Approaches to Identity in Sport
2020
Welcome to this Special Issue of Journal of Sport Psychology in Action, which offers new theoretical, methodological and applied considerations on what we (the editors) regard as the important topi...
PSYCHOLOGICZNE I PRAWNE ASPEKTY MOBBINGU W MIEJSCU PRACY
2018
Przemoc w miejscu pracy pojawia się z coraz większą a zarazem niepokojącą częstotliwością. Mobbing traktowany jest jako przykład patologii obserwowanej w organizacji. Stąd konieczność spojrzenia na mobbing w sposób wieloaspektowy. Celem artykułu jest przybliżenie psychologicznej natury zjawiska mobbingu, a także wskazanie na mobbing w kontekście polskiego prawa pracy. W artykule zwrócono uwagę na dwie przestrzenie, w jakich należy przyjrzeć się przemocy w organizacji. Pierwsza część artykułu poświęcona jest aspektom związanym z psychologią zdrowia i psychologią organizacji. Druga część artykułu poświęcona jest przestrzeni prawa pracy. W pierwszej części artykułu skupiono się na psychologicz…
Consumo de medicamentos en el embarazo y riesgo de anomalías congénitas en la Comunitat Valenciana
2017
Resumen: Antecedentes: El consumo de medicamentos durante el embarazo se ha incrementado en las últimas décadas. Objetivo: Identificar el riesgo de anomalías congénitas (AC) asociado a la utilización de medicamentos en atención ambulatoria en embarazadas residentes en la Comunitat Valenciana. Métodos: Estudio de casos-controles, considerando caso a menores de un año nacidos vivos en 2009-2010 diagnosticados de AC y residentes en la Comunitat Valenciana, obtenidos del registro poblacional de AC. Los controles se seleccionaron del Registro de Metabolopatías y la medicación prescrita y dispensada se obtuvo del módulo Gestión Integral de Prestación Farmacéutica. Se calcularon las odds ratio (OR…
What Are the Success Factors of Multilingual Families? Relationships Between Linguistic Attitudes and Community Dynamics
2021
The research focuses on the influence of emotional, cognitive, and social climate on the language choices of multilingual families, and the impact they can have on their general well-being, intergenerational relationships, and the community context. The methodological framework of reference is Grounded Theory. Collected data concern language practices, attitudes, emotions, and generational, trigenerational, and social interactive dynamics of multilingual families. The results include key insights into the variables underlying the linguistic attitudes of multicultural families. Two Network Views suggest that linguistic attitudes, such as the conscious management of specific and complex dynam…
Betulinic Acid Exerts Cytotoxic Activity Against Multidrug-Resistant Tumor Cells via Targeting Autocrine Motility Factor Receptor (AMFR).
2018
Betulinic acid (BetA) is a naturally occurring pentacyclic triterpene isolated from the outer bark of white-barked birch trees and many other medicinal plants. Here, we studied betulinic acid's cytotoxic activity against drug-resistant tumor cell lines. P-glycoprotein (MDR1/ABCB1) and BCRP (ABCG2) are known ATP-binding cassette (ABC) drug transporters that mediating MDR. ABCB5 is a close relative to ABCB1, which also mediates MDR. Constitutive activation of the EGF receptor is tightly linked to the development of chemotherapeutic resistance. BetA inhibited P-gp, BCRP, ABCB5 and mutation activated EGFR overexpressing cells with similar efficacy as their drug-sensitive parental counterparts. …
Echovirus 1 internalization negatively regulates epidermal growth factor receptor downregulation
2016
We have demonstrated previously that the human picornavirus Echovirus 1 (EV1) triggers an infectious internalization pathway that follows closely, but seems to stay separate, from the epidermal growth factor receptor (EGFR) pathway triggered by epidermal growth factor (EGF). Here, we confirmed by using live and confocal microscopy that EGFR and EV1 vesicles are following intimately each other but are distinct entities with different degradation kinetics. We show here that despite being sorted to different pathways and located in distinct endosomes, EV1 inhibits EGFR downregulation. Simultaneous treatment with EV1 and EGF led to an accumulation of EGFR in cytoplasmic endosomes, which was evi…