Search results for "FAILURE"

showing 10 items of 1977 documents

Metabolic and Vascular Effect of the Mediterranean Diet

2019

Several studies indicated how dietary patterns that were obtained from nutritional cluster analysis can predict disease risk or mortality. Low-grade chronic inflammation represents a background pathogenetic mechanism linking metabolic risk factors to increased risk of chronic degenerative diseases. A Mediterranean diet (MeDi) style has been reported as associated with a lower degree of inflammation biomarkers and with a protective role on cardiovascular and cerebrovascular events. There is heterogeneity in defining the MedDiet, and it can, owing to its complexity, be considered as an exposome with thousands of nutrients and phytochemicals. Recently, it has been reported a novel positive ass…

EpigenomicsMale0301 basic medicineMediterranean dietPhysiologyBlood lipidsBlood PressureReview030204 cardiovascular system & hematologyDiet MediterraneanBody Mass IndexEpigenesis Geneticlcsh:ChemistryTranscriptome0302 clinical medicineMedicinelcsh:QH301-705.5SpectroscopyRandomized Controlled Trials as TopicEpigenomicsIncidenceGeneral MedicineLipidLipidsComputer Science ApplicationsFemaledietary patternWaist CircumferenceHumancardiovascular riskExposomeEpigenomicCatalysisInorganic Chemistry03 medical and health sciencesDiabetes mellitusHumansPhysical and Theoretical ChemistryMolecular BiologyAgedHeart Failurebusiness.industryMechanism (biology)Organic Chemistrymediterranean dietBiomarkermedicine.disease030104 developmental biologylcsh:Biology (General)lcsh:QD1-999businessBody mass indexBiomarkersInternational Journal of Molecular Sciences
researchProduct

COVID-19 disease - Temporal analyses of complete blood count parameters over course of illness, and relationship to patient demographics and manageme…

2020

Background Detailed temporal analyses of complete (full) blood count (CBC) parameters, their evolution and relationship to patient age, gender, co-morbidities and management outcomes in survivors and non-survivors with COVID-19 disease, could identify prognostic clinical biomarkers. Methods From 29 January 2020 until 28 March 2020, we performed a longitudinal cohort study of COVID-19 inpatients at the Italian National Institute for Infectious Diseases, Rome, Italy. 9 CBC parameters were studied as continuous variables [neutrophils, lymphocytes, monocytes, platelets, mean platelet volume, red blood cell count, haemoglobin concentration, mean red blood cell volume and red blood cell distribu…

Erythrocyte IndicesMaleViral DiseasesNeutrophilsPhysiologyclinical biomarkersRomeDisease030204 cardiovascular system & hematologyCardiovascular MedicineCohort StudiesLeukocyte CountWhite Blood Cells0302 clinical medicineMedical ConditionsAnimal CellsMedicine and Health SciencesRenal Failure030212 general & internal medicineLongitudinal StudiesLymphocytesSurvivorsCOPDMultidisciplinarymedicine.diagnostic_testQRComplete blood countMiddle AgedPrognosisBody FluidsInfectious DiseasesBloodSettore MED/38 - PEDIATRIA GENERALE E SPECIALISTICAPhysiological Parameterscovid-19; blood cell count; clinical biomarkerscovid-19Cardiovascular DiseasesNephrologyMedicineFemaleCellular TypesAnatomyMean Platelet VolumeCohort studyResearch ArticlePlateletsmedicine.medical_specialtyScienceImmune CellsImmunologyCardiology03 medical and health sciencesInternal medicinemedicineHumansObesityMean platelet volumeDemographyInflammationBlood Cellsbusiness.industryBody WeightBiology and Life SciencesRed blood cell distribution widthCovid 19Cell Biologymedicine.diseaseObesityBlood CountsAnisocytosisblood cell countbusinessBiomarkers
researchProduct

Estudio de la insolvencia empresarial en las cooperativas mediante técnicas multivariantes

2020

One of the consequences of the current economic crisis is a significant rise in business failures, which is fueling the interest of researchers and users for its analysis, review and update of the traditional models.In reviewing the financial literature on business failure in our country, we noticed that the are very few studies focusing exclusively on cooperative enterprises, although this kind of companies have a broad presence in our country. This significant lack of studies on this kind of business, the recent availability of large databases and the current economic circumstances have influenced us to undertake this work. The main paper objective focuses on the estimation of appropriate…

EstimationEconomics and EconometricsEconomyWork (electrical)EconomicsBusiness failureIndustrial organizationStudies of Applied Economics
researchProduct

Innovations in medical care and mortality trends from four circulatory diseases between 1970 and 2005

2013

Background: Governments have identified innovation in pharmaceuticals and medical technology as a priority for health policy. Although the contribution of medical care to health has been studied extensively in clinical settings, much less is known about its contribution to population health. We examine how innovations in the management of four circulatory disorders have influenced trends in cause-specific mortality at the population level. Methods: Based on literature reviews, we selected six medical innovations with proven effectiveness against hypertension, ischaemic heart disease, heart failure and cerebrovascular disease. We combined data on the timing of these innovations and cause-spe…

Estoniamedicine.medical_specialtyTime FactorsPopulation levelPsychological interventionMyocardial IschemiaPopulation healthMedical careSDG 3 - Good Health and Well-beingEnvironmental healthCause of DeathGermanySurveys and QuestionnairesMedicineHumansMortalityIntensive care medicineMortality trendsHealth policyNetherlandsHeart FailureSwedenbusiness.industryTherapies InvestigationalPublic Health Environmental and Occupational HealthHealth technologymedicine.diseaseUnited KingdomEuropeCerebrovascular DisordersSpainHeart failureHypertensionFrancebusinessEuropean Journal of Public Health
researchProduct

Taking Advantage of Selective Change Driven Processing for 3D Scanning

2013

This article deals with the application of the principles of SCD (Selective Change Driven) vision to 3D laser scanning. Two experimental sets have been implemented: one with a classical CMOS (Complementary Metal-Oxide Semiconductor) sensor, and the other one with a recently developed CMOS SCD sensor for comparative purposes, both using the technique known as Active Triangulation. An SCD sensor only delivers the pixels that have changed most, ordered by the magnitude of their change since their last readout. The 3D scanning method is based on the systematic search through the entire image to detect pixels that exceed a certain threshold, showing the SCD approach to be ideal for this applicat…

Event-based visionLaser scanningComputer scienceTransducers3d scanninglcsh:Chemical technologySensitivity and SpecificityBiochemistryArticleAnalytical Chemistrylaw.inventionPhotometryPhotometry (optics)Imaging Three-DimensionallawInformàticaNyquist–Shannon sampling theoremComputer visionlcsh:TP1-11853D scanningElectrical and Electronic Engineeringhigh-speed visual acquisitionInstrumentationPixelbusiness.industryLasers3D reconstructionReproducibility of ResultsSignal Processing Computer-AssistedEquipment DesignImage EnhancementLaserAtomic and Molecular Physics and OpticsEquipment Failure AnalysisTransducerSemiconductorsCMOSArtificial intelligencebusinessHigh-speed visual acquisitionevent-based visionSensors
researchProduct

Fostering novelty while reducing failure: Balancing the twin challenges of product innovation

2016

This paper aims to further our understanding of how the degrees of innovation novelty and innovation failure are connected. It argues that a better understanding of the specific predictors of innovation novelty and failure would improve our understanding of the innovation process and inform R&D managerial interventions to reduce the occurrences of failure and enhance radical innovation. This investigation draws on data on 5387 Spanish manufacturing firms from the 2009 Spanish Community Innovation Survey (CIS). Unlike prior studies which examine product innovation, degree of innovation novelty, and innovation failures in separate models, this study relies on a multivariate model to account f…

External sources of informationKnowledge managementR&D contractingProduct innovationbusiness.industry05 social sciencesInnovation processNoveltyInnovation failureR&D cooperation050905 science studiesProbability of failureManagement of Technology and Innovation0502 economics and businessInnovation noveltyORGANIZACION DE EMPRESASCorporate social responsibilityBusiness0509 other social sciencesBusiness and International ManagementCorporate social responsibility050203 business & managementApplied Psychology
researchProduct

Strengthening of steel-reinforced concrete structural elements by externally bonded FRP sheets and evaluation of their load carrying capacity to face…

2014

The paper has proposed a limit analysis procedure for a preliminary design of RC elements strengthened by externally bonded FRP sheets. The procedure, based on a multi-yield-criteria limit analysis approach, has led to a reliable prediction of peak loads and failure modes of the analyzed elements (slabs) by simultaneously considering the limit state of the constituent materials, so resulting very useful in many applications of engineering interest. The attention has been focused on hospital applications in which increment of service loads or realization of openings can weaken some structural elements that have been strengthened by FRP sheets.

FRP-strengthening systems RC slabs limit design FE-based 3D analysis Peak loads and failure modesSettore MED/36 - Diagnostica Per Immagini E RadioterapiaSettore ING-IND/15 - Disegno E Metodi Dell'Ingegneria Industriale
researchProduct

Label swapper device for spectral amplitude coded optical packet networks monolithically integrated on InP

2011

In this paper the design, fabrication and experimental characterization of an spectral amplitude coded (SAC) optical label swapper monolithically integrated on Indium Phosphide (InP) is presented. The device has a footprint of 4.8x1.5 mm 2 and is able to perform label swapping operations required in SAC at a speed of 155 Mbps. The device was manufactured in InP using a multiple purpose generic integration scheme. Compared to previous SAC label swapper demonstrations, using discrete component assembly, this label swapper chip operates two order of magnitudes faster. © 2011 Optical Society of America.

FabricationComputer sciencePacket networksPhosphinesIntegrationIndium phosphideIndiumSemiconductor laser theoryFootprint (electronics)chemistry.chemical_compoundDiscrete componentsSpectral amplitudeComputer Communication NetworksTEORIA DE LA SEÑAL Y COMUNICACIONESMonolithically integratedOptical labelsOptical amplifierSignal processingbusiness.industryExperimental characterizationInPOptical DevicesSignal Processing Computer-AssistedEquipment DesignChipIntegration schemeAtomic and Molecular Physics and OpticsOptical packet networksEquipment Failure Analysischemistryvisual_artElectronic componentvisual_art.visual_art_mediumIndium phosphideOptoelectronicsMonolithic integrated circuitsbusinessLabel swapping
researchProduct

Automatable sample fabrication process for pump-probe X-ray holographic imaging

2014

Soft X-ray holography is a recently developed imaging technique with sub-50 nm spatial resolution. Key advantages of this technique are magnetic and elemental sensitivity, compatibility with imaging at free electron laser facilities, and immunity to in-situ sample excitations and sample drift, which enables the reliable detection of relative changes between two images with a precision of a few nanometers. In X-ray holography, the main part of the experimental setup is integrated in the sample, which consequently requires a large number of fabrication steps. Here we present a generic design and an automatable fabrication process for samples suitable, and optimized for, efficient high resolut…

FabricationMaterials scienceImage qualityDynamic imagingHolographyComputingMethodologies_IMAGEPROCESSINGANDCOMPUTERVISIONHolography02 engineering and technologyIterative reconstruction01 natural scienceslaw.inventionOpticslaw0103 physical sciencesDigital image processing010306 general physicsImage resolutionLithographybusiness.industryEquipment Design021001 nanoscience & nanotechnologyAtomic and Molecular Physics and OpticsEquipment Failure AnalysisComputer-Aided DesignRadiographic Image Interpretation Computer-Assisted0210 nano-technologybusinessOptics Express
researchProduct

In-situ NDT testing procedure as an integral part of failure analysis of historical masonry arch bridges

2015

Abstract A nineteenth-century masonry arch bridge was analyzed as an illustrative example to explain the role of in-situ test campaigns in failure analysis and retrofit design. Test results were studied to find out the advantages of each technique, with the aim of proposing an optimized in-situ testing procedure. Standard static penetrometer, flat jack, thermographic and georadar in-situ tests were conducted. Traffic effects were analyzed by means of vibrational tests. The experimental analysis performed to investigate damage on the bridge structures shows the degree of reliability offered by each technique in evaluating specific information and reproducing the global behavior of the struct…

Failure analysisEngineeringFinite element methodDrawingBridge (nautical)law.inventionHistorical arch bridgeEngineering (all)lawNondestructive testingDiagnosisForensic engineeringGeneral Materials ScienceFailure analysiMasonryMasonry; Historical arch bridges; Failure analysis; Diagnosis; Drawing; Finite element methodReliability (statistics)business.industryGeneral EngineeringStructural engineeringMasonryHistorical arch bridgesPenetrometerFinite element methodMaterials Science (all)businessMasonry archDiagnosi
researchProduct