Search results for "FAMILY"

Impact of a physician-targeted letter on opioid prescribing.

2020

We study the effect of a physician-targeted nudge letter on opioid prescribing. In May 2017, the Social Insurance Institution of Finland sent a personal information letter to all physicians who had issued a prescription containing at least 100 tablets of paracetamol-codeine combination to a new patient. The aim of the letter was to draw the physicians’ attention to their prescribing practices and to decrease the size of the first codeine prescription. Using individual level register data and a difference-in-differences strategy, we estimate that the letter decreased the average number of tablets purchased by new patients by 12.5 percent and the probability of a first purchase being at least…

Experiences of people with memory disorders and their spouse carers on influencing formal care: “They ask my wife questions that they should ask me”

2021

Background People with memory disorders often need care and help from family carers and health and social care providers. Due to the deterioration of cognitive capacity and language skills, they may be unable to convey their thoughts and care preferences to other people. As a result, their agency may become restricted. We investigated the descriptions provided by people with memory disorders and spousal carers of their influence on care in encounters with formal care providers. Methods Qualitative thematic analysis was used to identify, analyze, and report themes that describe encounters with professionals in different social or healthcare environments. In-depth interview data were gathered…

Tobacco use prevalence, knowledge and attitudes, and tobacco cessation training among medical students: results of a pilot study of Global Health Pro…

2011

Aim The aims of this study were to examine tobacco use prevalence, knowledge and attitudes, and tobacco cessation training among students attending Italian medical schools using the Global Health Professions Student Survey approach and to identify possible factors associated with smoking status. Subjects and Methods A multicentre cross-sectional pilot study was carried out in five Italian Schools of Medicine from March to April 2009. Questionnaires were administered in anonymous, voluntary and self-administered form to third year students attending medical schools. The outcome measure was “being a current smoker”. A logistic regression was used to evaluate possible factors associated with s…

EMAS position statement: Predictors of premature and early natural menopause.

2019

Simoncini, Tommaso/0000-0002-2971-0079; Chung, Hsin-Fang/0000-0003-3261-5942; Mishra, Gita/0000-0001-9610-5904 WOS:000468709100014 PubMed ID: 31027683 Introduction: While the associations of genetic, reproductive and environmental factors with the timing of natural menopause have been extensively investigated, few epidemiological studies have specifically examined their association with premature (< 40 years) or early natural menopause (40-45 years). Aim: The aim of this position statement is to provide evidence on the predictors of premature and early natural menopause, as well as recommendations for the management of premature and early menopause and future research. Materials and methods…

Differential requirements for antigen or homeostatic cytokines for proliferation and differentiation of human Vgamma9Vdelta2 naive, memory and effect…

2005

We have compared four human subsets of Vgamma9Vdelta2 T cells, naive (T(naive), CD45RA(+)CD27(+)), central memory (T(CM), CD45RA(-)CD27(+)), effector memory (T(EM), CD45RA(-)CD27(-)) and terminally differentiated (T(EMRA), CD45RA(+)CD27(-)), for their capacity to proliferate and differentiate in response to antigen or homeostatic cytokines. Cytokine responsiveness and IL-15R expression were low in T(naive) cells and progressively increased from T(CM) to T(EM) and T(EMRA) cells. In contrast, the capacity to expand in response to antigen or cytokine stimulation showed a reciprocal pattern and was associated with resistance to cell death and Bcl-2 expression. Whereas antigen-stimulated cells a…

Descriptive study on subjective experience of genetic testing with respect to relationship, family planning and psychosocial wellbeing among women wi…

2021

AbstractBackgroundDue to increased risk of endometrial and ovarian cancer, women belonging to known Lynch Syndrome (LS) families are recommended to undergo germline testing. Current practice in Finland is to offer counselling to women with pathogenic variant and advocate risk-reducing surgery (RRS) after completion of childbirth. The present study aimed to clarify the impacts of positive germline testing on family planning and reproductive decisions of these women, which are relatively unknown.MethodsSeventy-nine carriers of germline MMR gene pathogenic variant (path_MMR)were identified from the Finnish LS Registry as having genetic testing performed before the age of 45 years and not havin…

Merimiesten vaimot, naisten toimijuus ja perheiden toimeentuloehdot 1800-luvun suomalaisessa rannikkokaupungissa

2016

Amplicon-based high-throughput pooled sequencing identifies mutations in CYP7B1 and SPG7 in sporadic spastic paraplegia patients

2011

Hereditary spastic paraplegia (HSP) is a neurodegenerative disorder defined clinically by progressive lower limb spasticity and weakness. HSP is a genetically highly heterogeneous condition with at least 46 gene loci identified so far, involving X-linked, autosomal recessive (AR) and autosomal dominant inheritance. For correct diagnosis, molecular testing is essential because clinical parameters by themselves are not reliable to differentiate HSP forms. The purpose of this study was to establish amplicon-based high-throughput genotyping for AR-HSP. A sample of 187 index cases with apparently sporadic or recessive spastic paraplegia were analyzed by applying an array-based amplification stra…

Zagraniczne migracje kobiet a problemy rodziny i małżeństwa

2019

W artykule na podstawie badań jakościowych (wywiady, listy) i ilościowych przedstawiono refleksje i wspomnienia kobiet migrantek dotyczące ich rodzin i małżeństwa. Podejmując się analizy teoretycznej tych badań, wzięto pod uwagę teorię roli jako narzędzie do wyjaśniania zja-wisk. Teoria ta została zmodyfikowana poprzez dodanie innych, pozaludzkich (non-human) partne-rów roli, wobec których rola migrantki jest konstruowana i odgrywana. Wyjazd za granicę nie rozwiązuje konfliktumiędzy rolami rodzinnymi, małżeńskimi a zawodowymi, może go jedynie nasilać

INDOVINA CHI VIENE A CENA? QUESTIONI PSICO-SOCIO-GIURIDICHE NEL CICLO DI VITA DELLA COPPIA MISTA

2013

La famiglia, gruppo sociale con storia e che crea storia (Scabini, 1985), è stata negli anni protagonista di numerose trasformazioni nella sua struttura e nelle sue funzioni. Tra le nuove forme familiari oggetto di ricerca in campo psico-sociale vi è le coppia mista determinata anchʾessa da fenomeni demografici ed economici che, a loro volta, hanno richiesto adattamenti sociali e interventi legislativi ad hoc. Lʾanalisi delle caratteristiche della coppia mista consente di esplorare la praticabilità dellʾintegrazione di differenti esperienze culturali a livello di rapporto di coppia, familiare e sociale (Scabini, Regalia e Giuliani, 2007), esprimendo il livello più profondo dʾincontro tra cu…