Search results for "FAST"
showing 10 items of 821 documents
Oral manifestations of inflammatory bowel disease
2017
Inflammatory bowel diseases (IBD), including Crohn’s disease and ulcerative colitis, have important extraintestinal manifestations, notably in the oral cavity. These oral manifestations can constitute important clinical clues in the diagnosis and management of IBD, and include changes at the immune and bacterial levels. Aphthous ulcers, pyostomatitis vegetans, cobblestoning and gingivitis are important oral findings frequently observed in IBD patients. Their presentations vary considerably and might be well diagnosed and distinguished from other oral lesions. Infections, drug side effects, deficiencies in some nutrients and many other diseases involved with oral manifestations should also b…
Controlling Floquet states on ultrashort time scales
2022
AbstractThe advent of ultrafast laser science offers the unique opportunity to combine Floquet engineering with extreme time resolution, further pushing the optical control of matter into the petahertz domain. However, what is the shortest driving pulse for which Floquet states can be realised remains an unsolved matter, thus limiting the application of Floquet theory to pulses composed by many optical cycles. Here we ionized Ne atoms with few-femtosecond pulses of selected time duration and show that a Floquet state can be observed already with a driving field that lasts for only 10 cycles. For shorter pulses, down to 2 cycles, the finite lifetime of the driven state can still be explained…
The polygenic nature of hypertriglyceridaemia: implications for definition, diagnosis, and management.
2014
Item does not contain fulltext Plasma triglyceride concentration is a biomarker for circulating triglyceride-rich lipoproteins and their metabolic remnants. Common mild-to-moderate hypertriglyceridaemia is typically multigenic, and results from the cumulative burden of common and rare variants in more than 30 genes, as quantified by genetic risk scores. Rare autosomal recessive monogenic hypertriglyceridaemia can result from large-effect mutations in six different genes. Hypertriglyceridaemia is exacerbated by non-genetic factors. On the basis of recent genetic data, we redefine the disorder into two states: severe (triglyceride concentration >10 mmol/L), which is more likely to have a mono…
The Fatty Liver Assessment in Germany (FLAG) cohort study identifies large heterogeneity in NAFLD care
2020
Background & Aims NAFLD is a growing health concern. The aim of the Fatty Liver Assessment in Germany (FLAG) study was to assess disease burden and provide data on the standard of care from secondary care. Methods The FLAG study is an observational real-world study in patients with NAFLD enrolled at 13 centres across Germany. Severity of disease was assessed by non-invasive surrogate scores and data recorded at baseline and 12 months. Results In this study, 507 patients (mean age 53 years; 47% women) were enrolled. According to fibrosis-4 index, 64%, 26%, and 10% of the patients had no significant fibrosis, indeterminate stage, and advanced fibrosis, respectively. Patients with advanced fib…
Dynamic packet scheduling performance in UTRA Long Term Evolution downlink
2008
In this paper we evaluate the performance of dynamic Packet Scheduling (PS) of 3GPP UTRAN Long Term Evolution (LTE) Downlink. Packet scheduling is of utmost importance in 3G LTE, because all traffic types with different Quality of Service requirements are competing of the resources. We present a decoupled time and frequency domain packet scheduling framework for LTE downlink. Simulation results with three basic packet scheduler combinations with different amount of fairness are presented in four different 3GPP macro simulation cases to show the both extremes in tradeoff between fairness and spectral efficiency. In addition, the effect of multiuser diversity on packet scheduling performance …
Evaluation of nitric oxide metabolites in a group of subjects with metabolic syndrome.
2012
Abstract Aim To evaluate the concentration of metabolites (NO2−, NO3−) of nitric oxide (NO) in metabolic syndrome (MS). Materials and methods We enrolled 106 subjects (45 women and 61 men) with MS of which 43 (14 women and 27 men) with diabetes mellitus and 63 (31 women and 32 men) without diabetes mellitus, and 54 subjects (19 women and 35 men) as control group. The nitric oxide metabolites (nitrite + nitrate = NOx) were evaluated employing the Griess reagent. Results In the whole group of MS subjects was evident, in comparison with control group, a significant increase in NOx. The same finding was also present between control group and diabetic subjects with MS and between control group a…
Design of All-Normal Dispersion Microstructured Optical Fiber on Silica Platform for Generation of Pulse-Preserving Supercontinuum Under Excitation a…
2017
We investigated numerically the possibility of all normal dispersion fiber design for near-infrared supercontinuum generation based on a standard air-silica microstructure. The design procedure includes finding of target dispersion profile and subsequent finding of appropriate geometrical fiber design by inverse dispersion engineering. It was shown that the tailoring of dispersion profile could increase the spectral width of generated supercontinuum while maintaining perfect spectral flatness. Conditions necessary for wide and flat supercontinuum generation as well as restrictions imposed by chosen materials were discussed. As a result of design and optimization procedure, an air-silica des…
Performance of a high repetition pulse rate laser system for in-gas-jet laser ionization studies with the Leuven laser ion source @ LISOL
2012
The Leuven Isotope Separator On-Line (LISOL) facility at the Cyclotron Research Center (CRC) Louvain-la-Neuve; The laser ionization efficiency of the Leuven gas cell-based laser ion source was investigated under on- and off-line conditions using two distinctly different laser setups: a low-repetition rate dye laser system and a high-repetition rate Ti:sapphire laser system. A systematic study of the ion signal dependence on repetition rate and laser pulse energy was performed in off-line tests using stable cobalt and copper isotopes. These studies also included in-gas-jet laser spectroscopy measurements on the hyperfine structure of 63Cu. A final run under on-line conditions in which the ra…
Thermal annealing and transformation of dimer F centers in neutron-irradiated Al2O3 single crystals
2020
This work has been carried out within the framework of the EUROfusion Consortium and has received funding from the Euratom research and training programme 2014-2018 and 2019-2020 under grant agreement No 633053. The views and opinions expressed herein do not necessarily reflect those of the European Commission. In addition, the research leading to these results has received funding from the Estonian Research Council grant (PUT PRG619).
Theoretical and experimental study of primary radiation defects in KNbO3 perovskite crystals
2000
Abstract The results of large-scale computer simulations of point defects – F-type electron centers and hole polarons bound to a potassium vacancy – in perovskite KNbO3 crystals are presented. One-site polarons and two-site (molecular) polarons are expected to coexist, both are characterized by close absorption energies around 1 eV. The transient absorption spectra and decay kinetics observed after ns-pulsed electron beam irradiation have been measured for different KNbO3 crystals. The relaxation kinetics of the optical density vary considerably for different impurity concentrations and sample stoichiometries. Experimental data are discussed in the light of the presented calculations.