Search results for "FAST"
showing 10 items of 821 documents
Fasting renders immunotherapy effective against low-immunogenic breast cancer while reducing side effects
2022
Immunotherapy is improving the prognosis and survival of cancer patients, but despite encouraging out-comes in different cancers, the majority of tumors are resistant to it, and the immunotherapy combinations are often accompanied by severe side effects. Here, we show that a periodic fasting-mimicking diet (FMD) can act on the tumor microenvironment and increase the efficacy of immunotherapy (anti-PD-L1 and anti-OX40) against the poorly immunogenic triple-negative breast tumors (TNBCs) by expanding early exhausted effector T cells, switching the cancer metabolism from glycolytic to respiratory, and reducing collagen depo-sition. Furthermore, FMD reduces the occurrence of immune-related adve…
Subpicosecond Laser Spectroscopy of Blue-Light-Induced Absorption in KNbO3 and LiNbO3
2000
Pulses of 427-nm light from am amplified Ti:sapphire frequency-doubled laser are absorbed in two-photon band-gap excitations of KNbO3 and LiNbO3. Induced absorption spectra measured in the visible and recently extended in the infrared have been recorded as a function of delay from 0 to 250 ps after two-photon blue excitation. Samples include stoichiometric as well as congruent LiNbO3. Comparison is made to transient absorption in the nanosecond and longer time range induced by electron pulses of~10 ns width and 270 keV energy. Parts of the absorption can be attributed to bound and free polarons, including the intrinsic electron polaron.
Crayfish predation on mussels : an experimental approach
2013
Tässä työssä tutkittiin kokeellisesti rapujen simpukoihin kohdistuvaa predaatiota. Käytetyt rapulajit olivat jokirapu Astacus astacus ja amerikkalainen tulokaslaji täplärapu Pascifastacus leniusculus. Jokirapupredaatiota tutkittiin pikkujärvisimpukalla Anodonta anatina ja täplärapupredaatiota pikkujärvisimpukalla sekä jokihelmisimpukalla Margaritifera margaritifera Kokeissa ravut laitettiin yksittäin 15 litran läpivirtausaltaisiin simpukan/simpukoiden kanssa. Täplärapu osoittautui tehokkaammaksi predaattoriksi onnistuen aukaisemaan seitsemän 42:sta Anodontasta. Jokirapu ei saanut avattua yhtään 37:stä Anodontasta. Aukaisemisen ja pehmytosien syömisen lisäksi rapujen havaittiin nakertavan si…
Machinery Failure Approach and Spectral Analysis to Study the Reaction Time Dynamics over Consecutive Visual Stimuli: An Entropy-Based Model.
2020
[EN] The reaction times of individuals over consecutive visual stimuli have been studied using an entropy-based model and a failure machinery approach. The used tools include the fast Fourier transform and a spectral entropy analysis. The results indicate that the reaction times produced by the independently responding individuals to visual stimuli appear to be correlated. The spectral analysis and the entropy of the spectrum yield that there are features of similarity in the response times of each participant and among them. Furthermore, the analysis of the mistakes made by the participants during the reaction time experiments concluded that they follow a behavior which is consistent with …
Purification and structural characterisation of lipid transfer protein from red wine and grapes
2012
Lipid transfer proteins (LTP) play a major role in plant defence and are of particular interest due to their known ability to cause allergic reactions. These proteins are expressed in grapes and also remain detectable after vinification, especially in red wine. However, it remains unknown whether the protein undergoes any changes during the vinification process. Here, we present a purification method for LTPs from Dornfelder grapes and wine. By liquid-chromatography-mass spectroscopy (LC-MS/MS) we identified LTPs from two different species (Vitis vinifera and Vitis aestivalis). Additionally, the purified LTPs were characterised using spectrometric methods, confirming their high purity and s…
Vocabulary Gains of Mono- and Multilingual Learners in a Linguistically Diverse Setting: Results From a German-English Intervention With Inclusion of…
2018
Today, group settings (e.g., in kindergarten) are more linguistically-diverse than ever. However, concepts in language acquisition only rarely include this fact. This paper reports on the effects of a language intervention which is based on a concept specifically designed for linguistically-diverse settings („PROgramme for BI- and MUltilingual Children“; Festman and Rinker, 2014). The implementation of the programme and its outcomes are described with the example of a German-English-immersion kindergarten, which was in fact plurilingual. We aimed at supporting children’s acquisition of the two languages in parallel with inclusion of their home languages. Overall, 52 (mono-, bi-, and triling…
A Fast Handover Method for Real-Time Multimedia Services
2006
Mobile IPv6 (MIPv6) has been standardized for mobility management in the IPv6 network. When a mobile node changes its point of attachment in the IPv6 network, it experiences a time due MIPv6 procedures when it cannot receive or send any packets. This time called the handover delay might also cause packet loss resulting undesired quality-of-service degradation for various types of applications. The minimization of this delay is especially important for real-time applications. In this chapter we present a fast handover method called the flow-based fast handover for Mobile IPv6 (FFHMIPv6) to speed up the MIPv6 handover processes. FFHMIPv6 employs flow information and IPv6-in-IPv6 tunneling for…
Hot-spot detection and characterization of strombolian activity from MODIS infrared data
2014
Identifying and characterizing strombolian activity from space is a challenging task for satellite-based infrared systems. Stromboli volcano is a natural laboratory that offers a unique opportunity for refining thermal remote-sensing applications that involve transient phenomena and small to moderate hot-spots. A new simple and fast algorithm gave us the opportunity to revisit the MODIS-derived thermal output at Stromboli volcano over the last 13 years. The new algorithm includes both night-time and daytime data and shows high performance with the detection of small-amplitude thermal anomalies ( 1000 MW). The ...
Phase-shifting Gabor holography.
2009
We present a modified Gabor-like setup able to recover the complex amplitude distribution of the object wavefront from a set of inline recorded holograms. The proposed configuration is characterized by the insertion of a condenser lens and a spatial light modulator (SLM) into the classical Gabor configuration. The phase shift is introduced by the SLM that modulates the central spot (dc term) in an intermediate plane, without an additional reference beam. Experimental results validate the proposed method and produce superior results to the Gabor method.
Relations between multi-resolution analysis and quantum mechanics
2005
We discuss a procedure to construct multiresolution analyses (MRA) of L2 (R) starting from a given seed function h (s) which should satisfy some conditions. Our method, originally related to the quantum mechanical Hamiltonian of the fractional quantum Hall effect, is shown to be model independent. The role of a canonical map between certain canonically conjugate operators is discussed. This clarifies our previous procedure and makes much easier most of the original formulas, producing a convenient framework to produce examples of MRA. © 2005 American Institute of Physics.