Search results for "FCH"
showing 4 items of 4 documents
Metabolic disorders and inflammation are associated with familial combined hyperlipemia
2019
Background: Familial Combined Hyperlipidemia (FCH) is related to different metabolic disorders. The objective of this study was to evaluate the presence of alterations of hydrocarbonated metabolism and lipid profile together with inflammatory and adhesion molecules in subjects with FCH compared to controls. Methods: 75 HFC patients and 75 healthy individuals were studied. Glucose, insulin, HOMA-IR index and lipid parameters, in addition to anti-oxidized LDL antibodies (Anti ox-LDL), small and dense LDL (sdLDL) and HDL subfractions, proinflammatory cytokines and adhesion molecules were measured. Results: FCH patients showed higher levels of hydrocarbonated metabolism parameters, total choles…
FABP4 plasma levels are increased in familial combined hyperlipidemia
2010
The lipid profile of familial combined hyperlipidemia (FCHL) shares some characteristics with atherogenic dyslipidemia seen in diabetes, metabolic syndrome, and obesity. Adipocyte fatty acid-binding protein 4 (FABP4) appears to be a determinant of atherogenic dyslipidemia. We examined relationships between FABP4 plasma concentrations, dyslipidemia, and metabolic variables in patients with FCHL. We studied 273 unrelated FCHL patients and 118 control subjects. FABP4 was higher in FCHL than controls, with mean levels of 21.8 (10.1) microg/l and 19.2 (9.2) microg/l, respectively (adjusted P= 0.012). In FCHL, FABP4 correlated to body mass index (BMI), waist circumference, insulin levels, and hom…
Fogging effect correction of Gafchromic HD-V2 film response for its use in high-dose radiotherapy
2020
GAFChromic® HD-V2 film is a reliable dose measurement device, thin, flexible, inexpensive, simple to use and easy to analyze. The response in terms of net absorbance with respect to absorbed dose was found to be linear in a large dose range, which supports the feasibility of using the film dosimeters in many applications, such as radiotherapy. For its use, a "fogging" effect must be take into account since film response changes with time. To determine a calibration curve valid for any time, fogging effect was investigated for more than 400 days. A correction procedure allows the use of HD-V2 film dosimeters in high-dose radiotheraphy, as brachytherapy, and quality assurance (QA) procedures.
Response of GAFChromic® HD-V2 film dosimeter in 10-300 Gy dose range for radiation testing of electronic devices
2019
The study reported in this paper aimed to investigate the response of a GAFChromic? HD-V2 film dosimeter in the dose range between 10 and 300 Gy, normally used to perform irradiation tests on electronic devices with a 60Co gamma-ray irradiator. The well-defined linearity of response in terms of absorbance as a function of absorbed dose, easiness of handling and data analysis of irradiated dosimeters, reproducibility, stability, and insensitivity to visible light and most of the environmental parameters, make HD-V2 film a flexible, inexpensive and reliable dose measurement device. The study has shown a fogging effect of the dosimeter response since its value changes over time. Strategies and…