Search results for "FINE"
showing 10 items of 1800 documents
Air pollution and airport apron workers: A neglected occupational setting in epidemiological research.
2020
Abstract Introduction Airport apron workers are occupationally exposed to jet exhaust and major concern is related to the exposure to ultrafine particles (UFP) from aircrafts. To date, little attention has been given to occupational exposures to aircraft-related UFP, although aircraft engines have high emissions of ultrafine particles, which are orders of magnitude higher than residential exposure. UFP could possibly contribute to the development of cancer, heart disease, mental illness, and respiratory symptoms. In addition to particulate matter, apron workers are exposed to other polluting substances associated with vehicles, aircraft exhaust or direct fuel emissions. Methods We performed…
Effect of footwear on intramuscular EMG activity of plantar flexor muscles in walking
2020
One of the purposes of footwear is to assist locomotion, but some footwear types seem to restrict natural foot motion, which may affect the contribution of ankle plantar flexor muscles to propulsion. This study examined the effects of different footwear conditions on the activity of ankle plantar flexors during walking. Ten healthy habitually shod individuals walked overground in shoes, barefoot and in flip-flops while fine-wire electromyography (EMG) activity was recorded from flexor hallucis longus (FHL), soleus (SOL), and medial and lateral gastrocnemius (MG and LG) muscles. EMG signals were peak-normalised and analysed in the stance phase using Statistical Parametric Mapping (SPM). We f…
Detection of lymph node metastases in esophageal cancer.
2011
Lymph node status is the most important single prognostic factor in esophageal cancer. The detection of involved lymph nodes is therefore the key to cure. This article will provide a meta-analysis and metaregression analysis on the diagnostic performances of current lymph node-detection devices; discuss the recent status of the sentinel lymph node concept in esophageal cancer by the two sentinel node-mapping procedures (the radio-guided and the blue dye techniques) and the developing computed tomography (CT) lymphography; discuss the detection of micrometastases; and the potential clinical application of molecular-based patients' profiles. Combined use of endoscopic ultrasonography fine-nee…
Thyroid hormones induce sumoylation of the cold shock domain-containing protein PIPPin in developing rat brain and in cultured neurons.
2006
We previously identified a cold shock domain (CSD)-containing protein (PIPPin), expressed at high level in brain cells. PIPPin has the potential to undergo different post-translational modifications and might be a good candidate to regulate the synthesis of specific proteins in response to extracellular stimuli. Here we report the effects of thyroid hormone (T3) on PIPPin expression in developing rat brain. We found that a significant difference among euthyroid- and hypothyroid- newborn rats concerns sumoylation of nuclear PIPPin, that is abolished by hypothyroidism. Moreover, T3-dependence of PIPPin sumoylation has been confirmed in cortical neurons purified from brain cortices and culture…
Indicadores tempranos (0-36 meses) de riesgo de trastorno del espectro autista. Un estudio de revisión.
2018
La prevalencia del trastorno del espectro autista (TEA) ha aumentado de manera muy notable en los últimos años debido fundamentalmente a un aumento del conocimiento sobre el mismo por parte de los profesionales responsables de su identificación y/o diagnóstico.El presente trabajo tiene como objetivo realizar una revisión de los artículos publicados en 2018 que se han propuesto identificar entre los 0 y 36 meses de vida predictores fiables de la posterior aparición del TEA.Se realizó una búsqueda en PsycInfo en la que se localizaron 8 estudios empíricos diseñados para evaluar el poder predictivo de estos indicadores tempranos.En estos estudios se identificaron diferentes síntomas que se cons…
<tocheading>Original Article</tocheading>
1999
In this double-blind clinical trial 429 patients (217 terbinafine and 212 clotrimazole) were randomized to receive twice daily terbinafine 1% topical solution for 1 week followed by a vehicle application for 3 weeks, or 1% clotrimazole solution for 4 weeks. Patients were evaluated clinically and mycologically at baseline and then at weeks one, two, four (end of treatment), and eight (end of follow-up). To be evaluable the patient needed to have a positive culture for a dermatophyte and positive KOH microscopy and a clinical diagnosis of tinea pedis (interdigital type) at baseline. Effective treatment of tinea pedis was recorded in 181 of 217 (83%) of patients treated for 1 week with terbina…
Beclomethasone/formoterol fixed combination for the management of asthma: patient considerations.
2008
Gabriele Nicolini1, Nicola Scichilone2, Andrea Bizzi3, Alberto Papi4, Leonardo M Fabbri51Medical Department, Chiesi Farmaceutici, Parma, Italy; 2University of Palermo, DIMPEFINU, Palermo, Italy; 3Department of Scientific Affairs, Chiesi Farmaceutici, Parma, Italy; 4Research Center on Asthma and COPD, University of Ferrara, Ferrara, Italy; 5Section of Respiratory Diseases, University of Modena, Modena, ItalyAbstract: Drugs for asthma and other chronic obstructive diseases of the lungs should be preferably delivered by the inhalation route to match therapeutic effects with low systemic exposure. Inhaled drugs are delivered to the lungs via different devices, mainly metered dose inhalers and d…
Real-world EUROCRINE® registry data challenge the reliability of Bethesda cytopathology for thyroid surgery indication
2021
Abstract Objectives Fine-needle aspiration cytology (FNAC) is recommended by international guidelines for the preoperative evaluation of suspicious thyroid nodules >1 cm. Despite robust evidence from endocrine centers demonstrating the key role of FNAC results for the indication of surgery, the method is not routinely used in European clinics. The database EUROCRINE®, which was introduced in 2015 with the scope of registering operations of the endocrine system, allows for a large-scale analysis of the current service reality in Europe concerning FNAC use and associated accuracy. Methods Operations performed to “exclude malignancy”, registered from January 2015 to December 2018 in EUROCRI…
User experience and the security of graphical passwords
2015
Graafiset salasanat ovat lupaava vaihtoehto alfanumeeriselle autentikaatiolle. Älypuhelinten ja muiden korkea resoluutioisten kosketusnäytöllisten laitteiden määrä on kasvussa ja alfanumeeriset salasanat ovat kehitetty alun perin näppäimistölle syötettäviksi. Tarkkuutta vaativa kirjoittaminen ei tällöin ole välttämättä käyttäjälle kaikkein mielekkäintä. Graafisia ja alfanumeerisia salasanoja on tutkittu muistin toiminnan sekä käytettävyyden näkökulmasta. Tutkielma on tehty kirjallisuuden pohjalta käyttäen apuna erilaisia tieteellisia julkaisuja sisältäviä tietokantoja, kuten IEE Explore ja ACM Digital Library - tietokantoja. Tutkielman tarkoituksena oli kuvata ja tutkia tieteellisten artikk…
El documental de intervención y su relación con la realidad histórica. Variaciones en el tiempo
2011
El cine se origina como documental, como documento con voluntad de registrar la realidad. El conocimiento de los dispositivos cinematograficos, no solo como instrumentos tecnicos, sino tambien como elementos narrativos y organizadores de discurso, permite servirse del texto filmico como fin y medio para intervenir en la realidad. A lo largo de la historia del cine documental diferentes practicas han posibilitado establecer una gradiente de intervencion. Algunas expresiones, como la tradicional “documental militante”, deben reescribirse para ocupar el lugar que les corresponde en esa aproximacion a la realidad. Palabras clave: Documental; intervencion; realidad; militante; cine. Key words : …