Search results for "FIT"

Financial winners and losers since the privatization of the English and Welsh water and sewerage industry: a profit decomposition approach

2020

Evaluating changes in profit, price and productivity over time can be of great importance for regulated water industries. We investigate the drivers of profit, price (capital, labour and other inputs) and productivity change (cost efficiency change, technical change and scale effect) and the recipients of productivity change (consumers, the business itself, employees and other resource suppliers) of the English and Welsh water and sewerage companies over the period of 1995–2016. The results indicate that the profit decreased over time due to the negative quantity effect, which offset the positive price effect. A further decomposition of the quantity effect illustrates the negative impact of…

Experimental results on the economic management of a smart microgrid

2020

The aim of this paper is to assess economic benefits deriving from the adoption of a smart microgrid. To this end, a case study consisting of 250 houses connected to the distribution network through a MV/LV transformer substation has been investigated and implemented in the experimental microgrid built at the Polytechnic University of Bari, Italy. The analysis has been performed by comparing three different energy providers: the utility grid, the utility grid with the inclusion of non-programmable renewables generators, and the inclusion of such residential loads into a smart microgrid. The obtained results demonstrated that with the adoption of a smart microgrid significant costs savings c…

Meta-heuristic Algorithms for Nesting Problem of Rectangular Pieces

2017

Abstract Nesting problems consist of placing multiple items onto larger shapes finding a good arrangement. The goal of the nesting process is to minimize the waste of material. It is common to assume, as in the present work, that the stock sheet has fixed width and infinite height, since in the real world a company may have to cut pieces from a roll of material. The complexity of such problems is often faced with a two-stage approach, so-called “hybrid algorithm”, combining a placement routine and a meta-heuristic algorithm. Starting from a given positioning sequence, the placement routine generates a non-overlapping configuration. The encoded solution is manipulated and modified by the met…

A survey on handling computationally expensive multiobjective optimization problems with evolutionary algorithms

2017

Evolutionary algorithms are widely used for solving multiobjective optimization problems but are often criticized because of a large number of function evaluations needed. Approximations, especially function approximations, also referred to as surrogates or metamodels are commonly used in the literature to reduce the computation time. This paper presents a survey of 45 different recent algorithms proposed in the literature between 2008 and 2016 to handle computationally expensive multiobjective optimization problems. Several algorithms are discussed based on what kind of an approximation such as problem, function or fitness approximation they use. Most emphasis is given to function approxim…

2020

Limited data are available regarding strength and endurance training adaptations to occupational physical performance during deployment. This study assessed acute training-induced changes in neuromuscular (electromyography; EMG) and metabolic (blood lactate, BLa) responses during a high-intensity military simulation test (MST), performed in the beginning (PRE) and at the end (POST) of a six-month crisis-management operation. MST time shortened (145 ± 21 vs. 129 ± 16 s, −10 ± 7%, p < 0.001) during the operation. Normalized muscle activity increased from PRE to POST in the hamstring muscles by 87 ± 146% (116 ± 52 vs. 195 ± 139%EMGMVC, p < 0.001) and in the quadriceps by 54 ± 81% (26 ± 8…

Modelling load-transmission mechanisms in axially loaded RC columns retrofitted with steel jackets

2018

The use of steel jacketing technique is a common practice for retrofitting existing reinforced concrete (RC) columns, as it allows increasing load-carrying capacity and ductility of the member. When the external jacket has no-end connections – i.e. the jacket is indirectly loaded- the load sustained by the column is transferred from the inner RC core to the external jacket through shear stresses along the contact surface. The assessment of this mechanism is quite complex, due to the marked non-linear behaviour of constituent materials and to the calibration of a proper shear stress-relative slip constitutive law of the concrete-to-steel interface. In this paper, a step-by-step analytical ap…

2020

Decreases in aerobic fitness during military operations have been observed in several studies. Thus, differences in training adaptations during a 6-month crisis-management operation were compared by using the change in endurance performance as the outcome measure. Sixty-six male soldiers volunteered for the study, consisting of pre–post assessments of blood biomarkers, body composition, physical performance, and the military simulation test (MST) performance. Physical training volume was self-reported. After the follow-up, the data were divided based on individual changes in endurance performance. Endurance performance was improved in the high-responder group (HiR, n = 25) and maintained or…

2018

Physical fitness is crucial to warfighters' performance in the battlefield. Previous studies have shown negative changes in their hormonal and neuromuscular responses induced by military field training (MFT). The purpose of this study was to investigate the changes in hormonal and immunological values and body composition during a prolonged MFT and to find out how warfighters' physical condition influences these changes. Conscripts (n = 49, age 20 ± 1 years, height 179 ± 9 cm, body mass 73.8 ± 7.8 kg, fat 12.6 ± 3.7% and BMI 23 kg/m²) were measured before, during, after MFT, and after a 4-day recovery period. Serum insulin-like growth factor-1 (IGF-1), tumor necrosis factor alpha (TNF-α), i…

Effect of Host Species on Topography of the Fitness Landscape for a Plant RNA Virus

2016

[EN] Adaptive fitness landscapes are a fundamental concept in evolutionary biology that relate the genotype of individuals with their fitness. At the end, the evolutionary fate of evolving populations depends on the topography of the landscape, that is, the number of accessible mutational pathways and of possible fitness peaks (i.e, adaptive solutions). For long time, fitness landscapes were only theoretical constructions due to a lack of precise information on the mapping between genotypes and phenotypes. In recent years, however, efforts have been devoted to characterize the properties of empirical fitness landscapes for individual proteins or for microbes adapting to artificial environme…

Indicaxanthin from Opuntia Ficus Indica (L. Mill) impairs melanoma cell proliferation, invasiveness, and tumor progression.

2018

Abstract Background: A strong, reciprocal crosstalk between inflammation and melanoma has rigorously been demonstrated in recent years, showing how crucial is a pro-inflammatory microenvironment to drive therapy resistance and metastasis. Purpose: We investigated on the effects of Indicaxanthin, a novel, anti-inflammatory and bioavailable phytochemical from Opuntia Ficus Indica fruits, against human melanoma both in vitro and in vivo. Study Design and Methods: The effects of indicaxanthin were evaluated against the proliferation of A375 human melanoma cell line and in a mice model of cutaneous melanoma. Cell proliferation was assessed by MTT assay, apoptosis by Annexin V-Fluorescein Isothio…