Search results for "FIX"

showing 10 items of 1335 documents

Mitotic figure counts are significantly overestimated in resection specimens of invasive breast carcinomas.

2013

Several authors have demonstrated an increased number of mitotic figures in breast cancer resection specimen when compared with biopsy material. This has been ascribed to a sampling artifact where biopsies are (i) either too small to allow formal mitotic figure counting or (ii) not necessarily taken form the proliferating tumor periphery. Herein, we propose a different explanation for this phenomenon. Biopsy and resection material of 52 invasive ductal carcinomas was studied. We counted mitotic figures in 10 representative high power fields and quantified MIB-1 immunohistochemistry by visual estimation, counting and image analysis. We found that mitotic figures were elevated by more than th…

Pathologymedicine.medical_specialtyMitotic indexTime FactorsTissue FixationBiopsyMitosisBreast NeoplasmsBiologyPathology and Forensic MedicineBreast cancerPredictive Value of TestsBiopsyCarcinomamedicineMitotic IndexHumansNeoplasm InvasivenessMetaphaseMitosisMastectomyCell Proliferationmedicine.diagnostic_testCarcinoma Ductal BreastReproducibility of ResultsCell cyclemedicine.diseaseImmunohistochemistryKi-67 AntigenMitotic FigureLinear ModelsFemaleNeoplasm GradingModern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc
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Untersuchungen zur Hepatitis B-Antigen(HBAg)-Fixation an peripheren Lymphocyten und isolierten Leberzellen bei Patienten mit entz�ndlichen Lebererkra…

1975

Bei 127 Patienten mit verschiedenen entzundlichen Lebererkrankungen wurde die Fixation von HBAg an peripheren Lymphocyten untersucht. Bei 60 von diesen Patienten wurden im Parallelansatz die Fixation von HBAg an peripheren Lymphocyten und isolierten Leberzellen sowie die Fixation von IgG an isolierten Leberzellen gepruft.

Pathologymedicine.medical_specialtybusiness.industryGeneral MedicineHepatitis Bmedicine.diseasePeripheralAntigenDrug DiscoveryMolecular MedicineMedicineIn patientbusinessGenetics (clinical)Fixation (histology)Klinische Wochenschrift
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An improved anatomical MRI technique with suppression of fixative fluid artifacts for the investigation of human postmortem brain phantoms

2016

PURPOSE Phantoms are often used to assess MR system stability in multicenter studies. Postmortem brain phantoms best replicate human brain anatomy, allowing for a combined assessment of the MR system and software chain for data analysis. However, a wash-out of fixative fluid affecting T1 values and thus T1-weighted sequences such as magnetization-prepared 180 degrees radiofrequency pulses and rapid gradient-echo (MP-RAGE) has been reported for brain phantoms, hampering their immediate use. The purpose of this study was the creation of anatomical data that provide the characteristics of conventional data while avoiding this artifact. THEORY AND METHODS Two brain phantoms were scanned at seve…

Pathologymedicine.medical_specialtymedicine.diagnostic_testPostmortem brainComputer scienceSystem stabilityMagnetic resonance imagingHuman brainequipment and suppliesSynthetic data030218 nuclear medicine & medical imaging03 medical and health sciences0302 clinical medicinemedicine.anatomical_structuremedicineRadiology Nuclear Medicine and imagingProton density030217 neurology & neurosurgeryFixativeBiomedical engineeringFixation (histology)Magnetic Resonance in Medicine
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On a construit un Rhône. Socio-ecological fix et paysages mouvants de 1945 à 2013

2018

With the explosion of urban waterfront revitalization projects in the developed world it is timely to reflect on the relations between cities and their rivers: how the rivers influenced development of the cities, how cities have treated their riverfronts since19th century, and how the spatial relations of city and river constrain and enable improved connectivity between urban populations and their rivers. Both celebrated as revitalizing neglected urban centers and criticized for displacing the disenfranchised populations, riverfront revitalization projects raise questions about what constitutes ‘restoration’ in cities, to what degree natural processes and ecological values can be restored i…

PaysagesGeohistoiresocio-ecological fix[SHS.GEO] Humanities and Social Sciences/GeographyAnalyse du discours[SHS.GEO]Humanities and Social Sciences/Geographypolitical ecologyComputingMilieux_MISCELLANEOUS[ SHS.GEO ] Humanities and Social Sciences/Geography
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Half-width plots, a simple tool to predict peak shape, reveal column kinetics and characterise chromatographic columns in liquid chromatography: Stat…

2013

Peak profiles in chromatography are characterised by their height, position, width and asymmetry; the two latter depend on the values of the left and right peak half-widths. Simple correlations have been found between the peak half-widths and the retention times. The representation of such correlations has been called half-width plots. For isocratic elution, the plots are parabolic, although often, the parabolas can be approximated to straight-lines. The plots can be obtained with the half-widths/retention time data for a set of solutes experiencing the same kinetics, eluted with a mobile phase at fixed or varying composition. When the analysed solutes experience different resistance to mas…

Peak profiles in chromatography are characterised by their height position width and asymmetry; the two latter depend on the values of the left and right peak half-widths. Simple correlations have been found between the peak half-widths and the retention times. The representation of such correlations has been called half-width plots. For isocratic elution the plots are parabolic although often the parabolas can be approximated to straight-lines. The plots can be obtained with the half-widths/retention time data for a set of solutes experiencing the same kinetics eluted with a mobile phase at fixed or varying composition. When the analysed solutes experience different resistance to mass transfer the plots will be solute dependent and should be obtained with the data for each solute eluted with mobile phases at varying composition. The half-width plots approach is a simple tool that facilitates the prediction of peak shape (width and asymmetry) with optimisation purposes reveal the interaction kinetics of solutes in different columns and characterise chromatographic columns. This work shows half-width plots for different situations in isocratic elution including the use of different flows the effect of temperature the modification of the stationary phase surface by an additive the existence of specific interactions within the column and the comparison of columns. The adaptation to gradient elution is also described. Previous knowledge on half-width plots is structured and analysed to which new results are added.Work (thermodynamics)Column characterisationmedia_common.quotation_subjectKineticsLiquid chromatographyAnalytical chemistryHalf-widthsInteraction kineticsBiochemistryAsymmetryAnalytical ChemistryPeak shapeColumn (typography)Position (vector)Mass transferPhase (matter)media_commonChromatographyElutionChemistryOrganic ChemistryGeneral MedicineModels TheoreticalKineticsPredictionChromatography LiquidJournal of Chromatography A
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Methanotrophy induces nitrogen fixation during peatland development

2013

Significance In peatlands, the external sources of nitrogen are mainly atmospheric, but the atmospheric nitrogen deposition alone cannot explain the long-term annual nitrogen accumulation rates to these ecosystems. Because of methodological problems, methane-induced fixation of atmospheric dinitrogen gas has been previously overlooked as an additional nitrogen input mechanism. We found that the activity of methane-oxidizing bacteria provides not only carbon but also nitrogen to peat mosses and, thus, contributes to carbon and nitrogen accumulation in peatlands, which store approximately one-third of the global soil carbon pool. Our results imply that nitrogen fixation in wetlands may be str…

PeateducationCarbon CycleCarbon cycleMireSphagnopsidaNitrogen cyclePrimary successionFinlandSoil Microbiology1172 Environmental sciencesAlphaproteobacteriaAnalysis of VarianceCarbon Isotopes4112 ForestryMultidisciplinaryNitrogen IsotopesbiologyEcologySphagnopsidata1183Carbon respirationNitrogen CycleBiological Sciences15. Life on landbiology.organism_classification13. Climate action1181 Ecology evolutionary biologyNitrogen fixationEnvironmental scienceta1181MethaneProceedings of the National Academy of Sciences of the United States of America
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Clinical outcomes of veneered zirconia anterior partial fixed dental prostheses: A 12-year prospective clinical trial

2019

Abstract Statement of problem Anterior veneered zirconia partial fixed dental prostheses (FDPs) have substituted for metal-ceramic to improve esthetics and biocompatibility. However, the material is susceptible to aging or hydrothermal degradation and to chipping of the feldspathic veneer. Whether these susceptibilities limit the clinical performance of anterior veneered zirconia FPDs is unclear. Purpose The purpose of this prospective clinical study was to analyze the mechanical and biologic behavior of zirconia partial FDPs in the anterior region over a 12-year follow-up period. Material and methods Twenty-seven 3- to 6-unit FDPs fabricated from zirconia veneered with feldspathic porcelai…

Periapical pathologyDentistryDental CariesEsthetics DentalAnterior regionDental Materials03 medical and health sciences0302 clinical medicinePeriodontal diseaseHumansMedicineDental Restoration FailureProspective StudiesSurvival rateBiological Productsbusiness.industryDental prosthesisClinical performance030206 dentistryDental PorcelainClinical trialDental VeneersDenture Partial FixedZirconiumOral SurgeryComplicationbusinessThe Journal of Prosthetic Dentistry
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Sequential effects in the lexical decision task: the role of the item frequency of the previous trial.

2003

Two lexical decision experiments were conducted to determine whether there is a specific, localized influence of the item frequency of consecutive trials (i.e., first-order sequential effects) when the trials are not related to each other. Both low-frequency words and nonwords were influenced by the frequency of the precursor word (Experiment 1). In contrast, high-frequency words showed little sensitivity to the frequency of the precursor word (Experiment 2), although they showed longer reaction times for word trials preceded by a nonword trial. The presence of sequential effects in the lexical decision task suggests that participants shift their response criteria on a trial-by-trial basis.

PeriodicityDecision MakingContrast (statistics)Experimental and Cognitive PsychologyCognitionFixation OcularVocabularyLinguisticsWord lists by frequencyLexical decision taskReaction TimeHumansResponse criteriaPsychologyGeneral PsychologyWord (group theory)Cognitive psychologyThe Quarterly journal of experimental psychology. A, Human experimental psychology
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Modeling of the Salt Permeability in Fixed Charge Multilayer Membranes

2000

Permeability (earth sciences)MembraneMaterials scienceChemical engineeringFixed chargeElectrochemistryGeneral Materials ScienceSurfaces and InterfacesCondensed Matter PhysicsSpectroscopyLangmuir
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Solids and Hydraulic Retention Time Effect on N2O Emission from Moving-Bed Membrane Bioreactors

2018

Biological nutrient removal was operated at different solids (SRT) and hydraulic retention times (HRT) in order to assess their influence on nitrous oxide (N2O) emission from a hybrid moving-bed membrane bioreactor. The observed results show that the N2O production decreased when the SRT/HRT was decreased. The maximum N2O gaseous concentration was measured in the aerobic reactor at the end of phase I, and it decreased through phases II and III. From mass balances over the reactors of the system, the aerated (aerobic and membrane) reactors were the largest producers of N2O, showing that the greater part of N2O was produced during the nitrification process.

Petroleum engineeringHydraulic retention timeBiological nutrient removalSettore ICAR/03 - Ingegneria Sanitaria-AmbientaleChemistryGeneral Chemical Engineering0208 environmental biotechnologyN2OChemistry (all)02 engineering and technologyGeneral Chemistry010501 environmental sciences01 natural sciencesIndustrial and Manufacturing Engineering020801 environmental engineeringMembraneSolids retention timeBioreactorIntegrated fixed-film activated-sludge membrane bioreactorChemical Engineering (all)Moving bedHydraulic retention time0105 earth and related environmental sciences
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