Search results for "FLEX"

Mathematical Model Predicts Clinical Ocular Motor Syndromes

2003

: Clinical ocular motor syndromes were compared with ocular motor syndromes simulated by a mathematical model of the vestibuloocular reflex. The mathematical sensorimotor feedforward model of otolith control of three-dimensional binocular eye position is based on relevant anatomical connections of the vestibuloocular reflex from the utricles to extraocular eye muscles. This is the first attempt to simulate static ocular motor syndromes for unilateral utricular or vestibular nerve failure, lesions of the vestibular nucleus, and lesions of the ascending vestibuloocular reflex pathways. Comparison of the predicted syndromes with those found in patients with unilateral disorders of the vestibul…

Early improvement of executive test performance during antidepressant treatment predicts treatment outcome in patients with Major Depressive Disorder

2017

Executive dysfunctions frequently occur in patients with Major Depressive Disorder and have been shown to improve during effective antidepressant treatment. However, the time course of improvement and its relationship to treatment outcome is unknown. The aim of the study was to assess the test performance and clinical outcome by repetitive assessments of executive test procedures during antidepressant treatment. Executive test performance was assessed in 209 –patients with Major Depressive Disorder (mean age 39.3 ± 11.4 years) and 84 healthy controls five times in biweekly intervals from baseline to week 8. Patients were treated by a defined treatment algorithm within the early medication c…

A successful backward step correlates with hip flexion moment of supporting limb in elderly people.

2018

Purpose The objective of this study was to determine the positional relationship between the center of mass (COM) and the center of pressure (COP) at the time of step landing, and to examine their relationship with the joint moments exerted by the supporting limb, with regard to factors of the successful backward step response. Methods The study population comprised 8 community-dwelling elderly people that were observed to take successive multi steps after the landing of a backward stepping. Using a motion capture system and force plate, we measured the COM, COP and COM-COP deviation distance on landing during backward stepping. In addition, we measured the moment of the supporting limb joi…

Giant unruptured circumflex coronary artery aneurysms presenting as acute coronary syndrome

2020

Masseter reflex in childhood and adolescence.

2003

We report normative data of masseter reflex from a group of 54 children 2-16 years of age. For statistical analysis, the patients were divided into five age groups: 2-4, 5-7, 8-10, 11-13, and 14-16 years of age. A tap to the chin, using a hammer with a trigger device, elicited the masseter reflex. The response was recorded by surface electrodes. The onset latency and peak-to-peak amplitude of the averaged curve of eight reflex responses were measured. The reflex response could be recorded in all children and adolescents of all groups. The mean latency shortened from age 2 to 7 and was stable at the age of 8 years. As a sign of maturation, the increase of amplitude corresponded to the shorte…

Cognitive flexibility modulates maturation and music-training-related changes in neural sound discrimination

2015

Previous research has demonstrated that musicians show superior neural sound discrimination when compared to non-musicians, and that these changes emerge with accumulation of training. Our aim was to investigate whether individual differences in executive functions predict training-related changes in neural sound discrimination. We measured event-related potentials induced by sound changes coupled with tests for executive functions in musically trained and non-trained children aged 9-11 years and 13-15 years. High performance in a set-shifting task, indexing cognitive flexibility, was linked to enhanced maturation of neural sound discrimination in both musically trained and non-trained chil…

Maximal isometric strength and mobility among 75-year-old men and women.

1994

The purpose of this study was to examine the association between maximal isometric strength and mobility among 75-year-old men and women. All those born in 1914 and resident in the city of Jyvaskyla in August 1989 comprised the study group (n = 388); 355 persons were interviewed at their homes (92%): 101 men (81% of all male residents) and 186 women (75%) participated in the laboratory strength tests. As part of the home interview the person's mobility at home, on stairs and outdoors was assessed using a four-point scale:--1 able, 2--able with difficulty, 3--needs help, 4--unable. Poor mobility was more common among the drop-outs than among the strength-tested subjects in both sexes. Maxima…

Achilles tendon length changes during walking in long-term diabetes patients

2010

Diabetes leads to numerous side effects, including an increased density of collagen fibrils and thickening of the Achilles tendon. This may increase tissue stiffness and could affect stretch distribution between muscle and tendinous tissues during walking. The primary aim of this study was to examine stretch distribution between muscle and tendinous tissues in the medial gastrocnemius muscle-tendon unit in long-term diabetes patients and control subjects during walking.Achilles tendon length changes were investigated in 13 non-neuropathic diabetes patients and 12 controls, whilst walking at a self selected speed across a 10 m force platform. Electromyographic activity was recorded in the me…

Ipsilateral facial weakness in upper medullary infarction-supranuclear or infranuclear origin?

1999

We describe two patients with upper medullary infarctions showing ipsilateral facial weakness and relative sparing of the upper facial muscles. Electrophysiological follow-up using transcranial magnetic stimulation of the motor cortex in combination with stimulation of the peripheral facial nerve disclosed a supranuclear (corticofacial) tract lesion in one patient and a partial nuclear/infranuclear intra-axial facial nerve lesion in another.

Botulinum Toxin Type B Blocks Sudomotor Function Effectively: A 6 Month Follow Up

2003

This study analyzes the suppression of sweat gland activity by botulinum toxin type B. We injected botulinum toxin type B (between 2 and 1000 mouse units subcutaneously) in the lateral side of both lower legs in 15 healthy volunteers. Sweat tests were carried out before botulinum toxin type B injections, and at 3 wk, 3 mo, and 6 mo. We studied focal anhidrosis by iodine–starch staining and by capacitance hygrometry after carbachol iontophoresis, according to the quantitative sudomotor axon reflex test (QSART). Iodine starch staining indicated that a threshold dose of 8 mouse units botulinum toxin type B leads to anhidrotic skin spots (>4 cm2) after 3 wk. Duration of anhidrosis was prolonged…