Search results for "FLUID"

How amniotic fluid shapes early odor-guided responses to colostrum and milk (and more)

2016

Revue; Among the multiple transitions that characterize mammalian development, birth certainly is the most abrupt and spectacular. It is also the most challenging for newborns when one considers their high mortality rates in any mammalian species. Although evolution has selected newborn organisms that possess the physiological and behavioral keys leading to adapt to this harsh psychobiological challenge, their capabilities cannot be considered separately from the maternal organism and the environment she creates. Mammalian females provide indeed passive (physiological) and/or active (behavioral) assistance to complement and boost their offspring’s capacities. One notable strategy of mammali…

Le varianti A1 e A2 della ?-caseina non hanno un effetto significativo sul microbiota del latteThe A1 and A2 ?-casein variants have not impact on mil…

2020

Objective: Milk is composed by a complex microbiota which can be influenced by numerous factors such as the season, the diet, the type of litter, the facility. As well, the animal's genotype can affect the composition of the milk microbiota. In milk, ?-casein is characterized by a high-level of polymorphism. The aim of this study was to verify if A1 and A2 ?-casein variants could in- fluence the milk microbioma. Materials and methods: Thirty Holstein cows were genotyped for ?-casein locus and divided into three groups. In two different sea- sons, milk samples (individual and bulk tank for each experi- mental group) and mozzarella cheese were collected separately from each group. Bacterial D…

Effects of Minimalist Footwear and Foot Strike Patterns on Plantar Pressure during a Prolonged Running

2022

The use of minimalist shoes (MS) in running involves changes in running mechanics compared to conventional shoes (CS), but there is still little research analysing the effects of this footwear on plantar pressure, which could help to understand some risk injury factors. Moreover, there are no studies examining the effects of a prolonged running and foot strike patterns on baropodometric variables in MS. Therefore, the aim of this study was to analyse the changes produced using MS on plantar pressure during a prolonged running, as well as its interaction with the time and foot strike pattern. Twenty-one experienced minimalist runners (age 38 ± 10 years, MS running experience 2 ± 1 years) ran…

How Do Mobile ICTs Enable Organizational Fluidity : Toward a Theoretical Framework

2017

The focus of this theoretical paper is to investigate how mobile information and communication technologies (ICTs) give rise to the notion of organizational fluidity. Drawing upon previous literature, five affordances of mobile ICTs − mobility, connectedness, interoperability, identifiability, and personalization − are discussed. Delving into the concept of organizational fluidity, the paper captures three dimensions of organizational fluidity, namely, team fluidity, task fluidity, and control fluidity. The paper then develops propositions on how different combinations of the mobile ICT affordances influence each of the dimensions of organizational fluidity. The contributions and implicatio…

On the Finite Element Modeling of the Lumbar Spine: A Schematic Review

2023

Finite element modelling of the lumbar spine is a challenging problem. Lower back pain is among the most common pathologies in the global populations, owing to which the patient may need to undergo surgery. The latter may differ in nature and complexity because of spinal disease and patient contraindications (i.e., aging). Today, the understanding of spinal column biomechanics may lead to better comprehension of the disease progression as well as to the development of innovative therapeutic strategies. Better insight into the spine’s biomechanics would certainly guarantee an evolution of current device-based treatments. In this setting, the computational approach appears to be a remarkable …

Analisi numerica degli effetti della deformazione di membrane a scambio ionico sulla distribuzione dei fluidi in canali di Elettrodialisi

2019

L’elettrodialisi (ED) è una promettente tecnologia a membrana utilizzata in diversi campi, ad esempio nella dissalazione delle acque e nell’industria alimentare. L’ED usa un potenziale elettrico per indurre una migrazione selettiva di cationi ed anioni da una soluzione elettrolitica ad un’altra, sfruttando membrane a scambio ionico. Membrane anioniche e cationiche sono alternativamente collocate all’interno di una unità ED. A queste sono solitamente interposti spaziatori che prevengono il contatto tra le membrane e delineano i canali in cui scorrono le soluzioni. L’utilizzo di membrane profilate consente di costruire unità prive di tradizionali spaziatori a rete non conduttivi. In genere, l…

The numerical challenges in multiphysical modeling of laser welding with arbitrary Lagrangian-Eulerian method

2018

International audience; The interaction of high power laser beam with metallic materials produces a number of interconnected phenomena that represent a serious challenge for numerical modeling, especially for creation of auto-consistent models. Additional difficulty consists in lack of data on materials properties at the temperatures superior to their melting point. The present work summarizes the numerical challenges in creation and validation of free-surface models using ALE moving mesh coupled with heat transfer equation and Navier-Stokes fluid flow.

Extracellular vesicles isolated by cerebrospinal fluid as biomarkers of inflammation in multiple sclerosis and inflammatory neurological diseases.

2014

HLA-B27-restricted CD8 T cells derived from synovial fluids of patients with reactive arthritis and ankylosing spondylitis.

1993

Ankylosing spondylitis and seronegative spondylarthropathies such as Reiter's syndrome and reactive arthritis are strongly associated with HLA-B27. However, the mechanisms by which HLA-B27 is involved in disease susceptibility and pathogenesis are unknown. If the disease association is a consequence of HLA-B27's physiological function in antigen presentation, the disease should be mediated by cytotoxic T lymphocytes (CTLs) that recognise bacterial or self peptides presented by HLA-B27. Proof of this arthritogenic peptide model requires isolation of B27-restricted CD8 T cells from arthritic joints of patients with spondylarthropathies. An important question is whether "arthritogenic" bacteri…

HLA-B27-restricted cytotoxic T lymphocyte responses to arthritogenic enterobacteria or self-antigens are dominated by closely related TCRBV gene segm…

1996

Identification of the T-cell receptors (TCR) used by synovial cytotoxic T lymphocytes (CTL) of patients with reactive arthritis (ReA) may be crucial to better understanding the pathogenetic mechanism underlying the HLA-B27 association of spondylarthropathies. The authors, therefore, sequenced 25 TCRB chains from HLA-B27-restricted CD8+ CTL clones and two clonal lines specific for self- or Yersinia enterocolitica antigen isolated from synovial fluids of 3 HLA-B27+ patients with ReA and PBL of one healthy HLA-B27+ individual. Fourteen non-HLA-B27-restricted CTL served as controls. Both autoreactive and Y. enterocolitica specific HLA-B27-restricted CTL used a highly limited set of VB genes wit…