Search results for "FORMULATIONS"
showing 10 items of 31 documents
Improved test of time dilation in special relativity.
2003
An improved test of time dilation in special relativity has been performed using laser spectroscopy on fast ions at the heavy-ion storage-ring TSR in Heidelberg. The Doppler-shifted frequencies of a two-level transition in 7 Li + ions at v = 0.064c have been measured in the forward and backward direction to an accuracy of Δν/ν = 1 × 10 - 9 using collinear saturation spectroscopy. The result confirms the relativistic Doppler formula and sets a new limit of 2.2 × 10 - 7 for deviations from the time dilation factor γ S R = (1 - ν 2 /c 2 ) - 1 / 2 .
Numerical Hydrodynamics in Special Relativity
2003
This review is concerned with a discussion of numerical methods for the solution of the equations of special relativistic hydrodynamics (SRHD). Particular emphasis is put on a comprehensive review of the application of high-resolution shock-capturing methods in SRHD. Results obtained with different numerical SRHD methods are compared, and two astrophysical applications of SRHD flows are discussed. An evaluation of the various numerical methods is given and future developments are analyzed.
Introduction to Part IV
2018
When looking at the early development of relativity theory, one finds an astonishing number of contributions by mathematicians, some of which deeply influenced the work of leading theoretical physicists. Within the context of special relativity, Hermann Minkowski’s writings come immediately to mind (Walter 2008). Klein and Hilbert followed Minkowski’s ideas from their infancy, and both pursued some of their consequences after the latter’s premature death in January 1909. Two other figures with close ties to Gottingen, Max Born and Arnold Sommerfeld, were both instrumental in elaborating Minkowski’s 4-dimensional approach for physicists (Walter 2007). Born had been Minkowski’s assistant for …
Constructions of Nonagency in the Clients’ Initial Problem Formulations at the Outset of Psychotherapy
2019
This multiple case study investigated how clients construct nonagentic positions when formulating their problems in the beginning of their first psychotherapy session. The initial problem formulations of nine clients entering psychotherapy were analyzed with a detailed model drawing on discursive methodology, the 10 Discursive Tools model (10DT). We found ten problem formulation categories, each one distinguished by the tool from the 10DT model primarily used to construct nonagency. All clients gave several problem formulations from different categories and constructed nonagentic positions with a variety of discursive tools. When the resulting problem formulation categories were read in com…
Application of sequential injection analysis to pharmaceutical analysis.
2005
Sequential injection analysis is a well established tool for automation of pharmaceutical analysis. A short historical background of this technique is given as well as a brief discussion on the basic principles and potentials. The current applications of SIA in the pharmaceutical analysis are also described and discussed. The manifolds developed offer good analytical characteristics and are suitable for analysis of drug formulations, process analysis, drug-dissolution, drug-release testing and functional assays for screening potential drugs. The results obtained are in good agreement with those furnished by the application of the reference methods presented in the pharmacopoeias.
Multiscale modeling of polycrystalline materials: A boundary element approach to material degradation and fracture
2015
Abstract In this work, a two-scale approach to degradation and failure in polycrystalline materials is proposed. The formulation involves the engineering component level (macro-scale) and the material grain level (micro-scale). The macro-continuum is modeled using a three-dimensional boundary element formulation in which the presence of damage is formulated through an initial stress approach to account for the local softening in the neighborhood of points experiencing degradation at the micro-scale. The microscopic degradation is explicitly modeled by associating Representative Volume Elements (RVEs) to relevant points of the macro continuum, for representing the polycrystalline microstruct…
The Mathematicians’ Happy Hunting Ground: Einstein’s General Theory of Relativity
2004
There is hardly any doubt that for physics special relativity theory is of much greater consequence than the general theory. The reverse situation prevails with respect to mathematics: there special relativity theory had comparatively little, general relativity theory very considerable, influence, above all upon the development of a general scheme for differential geometry. —Hermann Weyl, “Relativity as a Stimulus to Mathematical Research,” pp. 536–537.
Seeing reality through Einstein's eyes: a teaching proposal for special relativity
2021
The teaching of Special Relativity is still a critical issue not only for students but also for teachers. In this paper, we describe the trial of a learning unit on the Special Relativity topic based on Minkowski's approach through spacetime diagrams, following the results in pedagogical researches in this field. The main innovation of our project consists of a mechanical instrument: it allows to physically and mechanically represent Lorentz’s transformations by hands, exploring the effects of a change of the reference frame. Teachers and students can deal “by eye” with unusual phenomena as the loss of simultaneity, time dilation, length contraction, relativistic addition of velocities and …
In vitro evaluation of glycol chitosan based formulations as oral delivery systems for efflux pump inhibition.
2017
Recently, we have reported that glycol chitosan (GCS) was able to reverse the P- glycoprotein (P-gp) efflux pump. The objective of the present study was to evaluate the potential of two GCS-based dosage forms (aqueous solution or nanoparticle suspension) for oral administration of the P-gp substrate Rho-123. A further aim of the present study was to assess the effect of the glycol chitosan-4-thiobutylamidine thiomer (GCS-TBA) on P-gp activity considering that the corresponding thiomer of chitosan series is a well-known P-gp inhibitor. Pre-treatment of Caco-2 cell monolayer with a GCS solution or GCS-based nanoparticles increased the absorptive transport of Rho-123 across the monolayer of 1.…
The Potential Use of Resveratrol for Cancer Prevention.
2019
In addition to the traditional treatments of cancer and cancer prevention, the use of natural compounds, especially those found in food, should be considered. To clarify if resveratrol has the potential for cancer prevention and the possibility of use in therapy, the following must be taken into account: data from epidemiology, clinical protocol (case and control), preclinical studies (lab animals), use of established cell lines as models of cancer cells, test tube assays (enzymes activities), and requirements of nanotechnologies in order to discover new drugs to fight cancer. From this perspective and future expected advances, more information is needed such as improved efficacy, methods o…