Search results for "FUNCTIONAL"

showing 10 items of 4822 documents

Signatures of selection in the genome of Swedish warmblood horses selected for sport performance

2019

Abstract Background A growing demand for improved physical skills and mental attitude in modern sport horses has led to strong selection for performance in many warmblood studbooks. The aim of this study was to detect genomic regions with low diversity, and therefore potentially under selection, in Swedish Warmblood horses (SWB) by analysing high-density SNP data. To investigate if such signatures could be the result of selection for equestrian sport performance, we compared our SWB SNP data with those from Exmoor ponies, a horse breed not selected for sport performance traits. Results The genomic scan for homozygous regions identified long runs of homozygosity (ROH) shared by more than 85%…

MaleGenotyping TechniquesPerformanceDIVERSITYBreedingRuns of HomozygosityHorseGenomeHISTORYInbreedingHOMOZYGOSITYGenetics & Heredity0303 health sciencesSnp dataeducation.field_of_studyHomozygoteRUNSASSOCIATIONGenomics04 agricultural and veterinary sciencesBreedDIFFERENTIATIONWarmbloodFemaleLife Sciences & BiomedicineTRAITSResearch ArticleSportsBiotechnologyGENESlcsh:QH426-470lcsh:BiotechnologyPopulationBiologyRuns of homozygosityPolymorphism Single Nucleotide03 medical and health scienceslcsh:TP248.13-248.65GeneticsAnimalsHorsesFunctional studieseducationSelection (genetic algorithm)030304 developmental biologyScience & Technology0402 animal and dairy scienceSelection signature040201 dairy & animal sciencelcsh:GeneticsBiotechnology & Applied MicrobiologyEvolutionary biologyWIDE SCANHaplotype homozygosityBMC Genomics
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The impact of structural and functional characteristics of social relations as determinants of functional decline.

2004

Objectives This study examines whether aspects of social relations at baseline are related to functional decline at 5-year follow-up among nondisabled old men and women. Methods The investigation is based on baseline and follow-up data on 651 nondisabled 75-year-old persons in Jyvaskyla (Finland) and Glostrup (Denmark). The analyses are performed separately for men and women. Possible selection problems were considered by using three outcome measures: first, functional decline among the survivors (n = 425); second, functional decline, including death, assuming that death is part of a general decline pattern (n = 565); and third, mortality (n = 651). Social relations were measured at baselin…

MaleGerontologyActivities of daily livingSocial PsychologyInterpersonal relationshipActivities of Daily LivingHumansDisabled PersonsInterpersonal RelationsFunctional declineSocial BehaviorBaseline (configuration management)Depression (differential diagnoses)AgedAged 80 and overSocial networkDepressionbusiness.industrySocial relationClinical PsychologyFemaleClubGeriatrics and GerontologybusinessPsychologyGerontologyFollow-Up Studies
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The reliability, validity, and sensitivity of the Edmonton Frail Scale (EFS) in older adults with foot disorders

2020

[Abstract] The Edmonton Frail Scale (EFS) is an index employed to measure alterations related to frailty. The main objective in this research was to develop the EFS short-form (EFS-SF) and to evaluate its validity, reliability, and sensitivity to predict frailty disability outcomes in elderly patients with foot disabilities. Results: Exploratory factor analysis (EFA) of the EFS-SF revealed the presence of three components, as in the original EFA. There were significant differences (p < 0.05) in the study population for several of the EFS and 5-item FRAIL scale indicators. The highest correlation (Pearson R = 0.871; p < 0.001) was found for the first component of the EFS-SF. Finally, the Cro…

MaleGerontologyAgingEdmonton Frail ScaleHealth StatusDeformidades adquiridas del pieAncianoNutritional StatusFoot deformitieselderlySensitivity and SpecificityFoot DiseasesCorrelationCognitionElderlyCronbach's alphaFoot diseasesHumansMedicineIn patientCiencias médicasAgedAged 80 and overEnfermedades del pieFrailtybusiness.industryReproducibility of ResultsCell Biologyfoot deformitiesRELIABILITY VALIDITYExploratory factor analysisMalformaciones del piefoot disordersCross-Sectional StudiesFunctional StatusScale (social sciences)Population studyFemaleFactor Analysis StatisticalbusinessVulnerabilidadAncianosFoot (unit)Research PaperAging
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Functional and Clinical Characteristics for Predicting Sarcopenia in Institutionalised Older Adults: Identifying Tools for Clinical Screening

2020

Background: Recently, the European Working Group on Sarcopenia in Older People (EWGSOP2) has updated the sarcopenia definition based on objective evaluation of muscle strength, mass and physical performance. The aim of this study was to analyse the relationship between sarcopenia and clinical aspects such as functionality, comorbidity, polypharmacy, hospitalisations and falls in order to support sarcopenia screening in institutionalised older adults, as well as to estimate the prevalence of sarcopenia in this population using the EWGSOP2 new algorithm. Methods: A multicentre cross-sectional study was conducted on institutionalised older adults (n = 132, 77.7% female, mean age 82 years). App…

MaleGerontologyFisioteràpiaBarthel indexHealth Toxicology and MutagenesisPopulationlcsh:MedicineArticleclinicalsarcopenia03 medical and health sciences0302 clinical medicinemedicineHumansMuscle Strength030212 general & internal medicineeducationGeriatric Assessmentfunctionalityolder adultsAgedAged 80 and overPolypharmacyInpatientseducation.field_of_studyHand StrengthClinical screeningbusiness.industrylcsh:RPublic Health Environmental and Occupational Healthmedicine.diseasemusculoskeletal systemComorbidityinstitutionalisedbody regionsCross-Sectional StudiesSarcopeniaFemaleObjective evaluationbusinesshuman activities030217 neurology & neurosurgeryComorbidity indexInternational Journal of Environmental Research and Public Health
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Association of physical fitness with quality of life in community-dwelling older adults aged 80 and over in Poland: a cross-sectional study

2021

Abstract Background Aging is a progressive and irreversible process that negatively affects the quality of life (QOL). Older adults face difficulties related to worsening health, lowering the level of physical and mental efficiency. We aimed to analyze the associations between physical fitness and QOL in Polish older adults considering sex differences. Methods This cross-sectional study was performed from March to August 2015. The sample consisted of 100 community-dwelling adults (67 women, 33 men) with a mean age of 82.94 ± 2.67 years. The World Health Organization QOL, Short Form questionnaire (WHOQOL-BREF), and the Fullerton Functional Fitness Test (FFFT) were used. Biometric data, socia…

MaleGerontologyFunctional traininglifestyleActivities of daily livingCross-sectional studymedicine.medical_treatmentPhysical fitnessQuality of lifemedicineHumansAerobic exercisepsychosocial factorsAgedAged 80 and overRehabilitationbusiness.industryRC952-954.6humanitiesTest (assessment)Cross-Sectional Studiesquality of lifeGeriatricsphysical fitnessFemaleIndependent LivingPolandGeriatrics and GerontologybusinessResearch ArticleBMC Geriatrics
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Lifetime leisure-time physical activity and the risk of depressive symptoms at the ages of 65–74years: The FIN-D2D survey

2011

To investigate the association between lifetime leisure-time physical activity (LTPA) and depressive symptoms (DS) based on the population-based FIN-D2D cross-sectional survey conducted in 2007.Nine hundred twenty seven randomly selected Finnish men and women aged 65-74 years were included in this study. DS were determined with the Beck Depression Inventory (≥10 points), and lifetime historical LTPA frequency from age 15 years onwards was recalled retrospectively.The frequency of LTPA was highest at the ages of 15-24 years in both the DS present and not present groups (14.6 times per month). LTPA frequency was significantly lower among those with DS compared with those without DS at the age…

MaleGerontologyTime FactorsPersonality InventoryEpidemiologyCross-sectional studyPopulationComorbidityGee03 medical and health sciencesAge DistributionLeisure Activities0302 clinical medicineRisk FactorsSurveys and QuestionnairesPrevalenceHumansMedicine030212 general & internal medicineFunctional abilityAge of OnseteducationExerciseGeriatric AssessmentFinlandAgedMetabolic SyndromeDepressive Disordereducation.field_of_studybusiness.industryIncidence (epidemiology)Public Health Environmental and Occupational HealthBeck Depression Inventoryta3141030229 sport sciencesMiddle Agedmedicine.diseaseComorbidityCross-Sectional StudiesSocial ClassChronic DiseaseRegression AnalysisFemaleSedentary BehaviorAge of onsetbusinesshuman activitiesPreventive Medicine
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Early emergence of deviant frontal fMRI activity for phonological processes in poor beginning readers.

2010

Phonological awareness refers to the ability to perceive and manipulate the sound structure of language and is especially important when children learn to read. Poor phonological awareness is considered the major cause for the emergence of reading difficulties. In this functional magnetic resonance imaging (fMRI) study, we examined the brain correlates of phonological processing in young beginning readers (aged 8.3+/-0.4 y, 2nd grade) with poor (25th percentile) or normal, age-appropriate reading skills (40th percentile) using a covert reading and mental letter substitution task. Letter substitution in words and nonwords induced pronounced activity in a left frontal language network related…

MaleHandwritingCognitive Neurosciencemedia_common.quotation_subjectInferior frontal gyrusPrefrontal CortexLateralization of brain functionFunctional LateralityDyslexiaPhonological awarenessReading (process)medicineImage Processing Computer-AssistedHumansChildmedia_commonBrain Mappingmedicine.diagnostic_testBrainElectroencephalographyMagnetic Resonance ImagingFrontal LobeNeurologyPhonological ruleReadingCovertFemaleFunctional magnetic resonance imagingPsychologyInsulaPsychomotor PerformanceCognitive psychologyNeuroImage
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Reward for food odors: An fMRI study of liking and wanting as a function of metabolic state and BMI

2014

Brain reward systems mediate liking and wanting for food reward. Here, we explore the differential involvement of the following structures for these two components: the ventral and dorsal striatopallidal area, orbitofrontal cortex (OFC), anterior insula, and anterior cingulate. Twelve healthy female participants were asked to rate pleasantness (liking of food and non-food odors) and the desire to eat (wanting of odor-evoked food) during event-related functional magnetic resonance imaging (fMRI). The subjective ratings and fMRI were performed in hunger and satiety states. Activations of regions-of-interest were compared as a function of task (liking vs. wanting), odor category (food vs. non-…

MaleHunger[ SDV.AEN ] Life Sciences [q-bio]/Food and NutritionBrain mappingSatiety ResponseNucleus Accumbensliking and wantingDevelopmental psychology0302 clinical medicinebrain reward systemsPrefrontal cortex2. Zero hunger0303 health sciencesBrain Mappingmedicine.diagnostic_testmetabolic statedigestive oral and skin physiologyGeneral MedicineMagnetic Resonance ImagingSatiety ResponseBrain stimulation rewardFemale[SDV.NEU]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]Psychologypsychological phenomena and processesAdultAdolescentCognitive NeurosciencePrefrontal CortexExperimental and Cognitive Psychologybody mass indexNucleus accumbensGlobus PallidusVentral pallidum03 medical and health sciencesFood PreferencesYoung AdultRewardmedicineReaction TimeHumans030304 developmental biologyfood odorsOriginal ArticlesMetabolismFood[ SDV.NEU ] Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]OdorantsOrbitofrontal cortexFunctional magnetic resonance imaging[SDV.AEN]Life Sciences [q-bio]/Food and Nutrition030217 neurology & neurosurgery
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Information decomposition of multichannel EMG to map functional interactions in the distributed motor system

2019

AbstractThe central nervous system needs to coordinate multiple muscles during postural control. Functional coordination is established through the neural circuitry that interconnects different muscles. Here we used multivariate information decomposition of multichannel EMG acquired from 14 healthy participants during postural tasks to investigate the neural interactions between muscles. A set of information measures were estimated from an instantaneous linear regression model and a time-lagged VAR model fitted to the EMG envelopes of 36 muscles. We used network analysis to quantify the structure of functional interactions between muscles and compared them across experimental conditions. Co…

MaleInformation transferMuscle networkNeurologyTransfer entropyComputer scienceSocial SciencesPostural controlFunctional connectivity0302 clinical medicineCONNECTIVITYNeural PathwaysDecomposition (computer science)Medicine and Health Sciencesmotor controlMuscle activityPostural Balance0303 health sciencesMuscle networksConditional mutual information05 social sciencesmedicine.anatomical_structureNeurologySYNCHRONIZATIONFemaleSpinal reflexAdultCORTEXmedicine.medical_specialtyCognitive NeurosciencePostureCentral nervous systemORGANIZATIONCognitive neuroscienceGRANGER CAUSALITY050105 experimental psychology03 medical and health sciencesReflexMotor systemCOHERENCEBiological neural networkmedicineHumans0501 psychology and cognitive sciencesMuscle SkeletalSet (psychology)signal processing030304 developmental biologyIDENTIFICATIONElectromyographyPostural controlMotor controlINPUTSMUSCLE SYNERGIESBRAIN NETWORKSSettore ING-INF/06 - Bioingegneria Elettronica E InformaticaNeuroscience030217 neurology & neurosurgery
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Item bias in self-reported functional ability among 75-year-old men and women in three Nordic localities.

1996

The purpose of this article is to analyse item bias in a measure of self-reported functional ability among 75-year-old people in three Nordic localities. The present item bias analysis examines whether the construction of a functional ability index from several variables results in bias in relation to geographical locality and gender. Information about self-reported functional ability was gathered from surveys on 75-year-old men and women in Glostrup (Denmark), Göteborg (Sweden) and Jyväskylä (Finland). The data were collected by structured home interviews about mobility and Physical activities of daily living (PADL) in relation to tiredness, reduced speed and dependency and combined into …

MaleItem biasActivities of daily livingPsychometricsDenmarkDependency Psychological03 medical and health sciences0302 clinical medicineQuality of lifeBiasActivities of Daily LivingDaily livingHumans030212 general & internal medicineFunctional abilityGeriatric AssessmentFatigueFinlandAgedSweden030505 public healthItem analysisPublic Health Environmental and Occupational HealthGeriatric assessmentQuality of LifeFemale0305 other medical sciencePsychologyDemographyScandinavian journal of social medicine
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