Search results for "FUNCTIONALS"

showing 10 items of 45 documents

Role of Solvent on Nonenzymatic Peptide Bond Formation Mechanisms and Kinetic Isotope Effects

2013

Based on the hypothesis that similar mechanisms are involved in the peptide bond formation in aqueous solution and in the ribosome, the aminolysis of esters in aqueous solution has been the subject of numerous studies as the reference reaction for the catalyzed process. The mechanisms proposed in the literature have been explored in the present paper by hybrid QM/MM molecular dynamics simulations. The free energy profiles have been computed with the QM region of the system described at semiempirical AM1 level and by DFT within the M06-2X functional. According to the results, the formation of adduct zwitterion species is a preliminary step required for all possible mechanisms. Then, from dif…

Models MolecularEster aminolysisMolecular Dynamics SimulationMethyl formateBiochemistryCatalysisMolecular dynamicschemistry.chemical_compoundColloid and Surface ChemistryAminolysisIsotopesComputational chemistryKinetic isotope effectOrganic chemistryPeptide bondConformational isomerismDensity functionalsChemistryAqueous-solutionGeneral ChemistryHydrazinolysisRibosomeTransition stateKineticsSolvation shellChorismate mutaseZwitterionSolventsTransition-state structuresPeptides
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Molecular Rearrangement of an Aza-Scorpiand Macrocycle Induced by pH: A Computational Study †

2016

Rearrangements and their control are a hot topic in supramolecular chemistry due to the possibilities that these phenomena open in the design of synthetic receptors and molecular machines. Macrocycle aza-scorpiands constitute an interesting system that can reorganize their spatial structure depending on pH variations or the presence of metal cations. In this study, the relative stabilities of these conformations were predicted computationally by semi-empirical and density functional theory approximations, and the reorganization from closed to open conformations was simulated by using the Monte Carlo multiple minimum method Financial support by the Spanish Ministerio de Economía y Competitiv…

Models MolecularMontecarlo Mètode deMonte Carlo method01 natural sciencessupramolecular chemistryMonte Carlo Multiple Minimumlcsh:ChemistryComputational chemistryaza-scorpiandsMolecular rearrangementpH controlled; supramolecular chemistry; synthetic receptors; aza-scorpiands; semi-empirical; Density Functional Theory; Monte Carlo Multiple Minimumlcsh:QH301-705.5semi-empiricalSpectroscopyDensity Functional TheoryDensity functionalsSpatial structureChemistryGeneral MedicineHydrogen-Ion ConcentrationMolecular machineComputer Science ApplicationsMonte Carlo methodpH controlledvisual_artsynthetic receptorsvisual_art.visual_art_mediumDensity functional theoryMonte Carlo MethodMacrocyclic CompoundsSupramolecular chemistry010402 general chemistryQuímica supramolecularCatalysisArticleInorganic ChemistryMetalQuantitative Biology::Subcellular ProcessesPhysical and Theoretical ChemistryMolecular BiologyAza CompoundsFuncional de densitat Teoria del010405 organic chemistryOrganic ChemistryComputational Biology0104 chemical scienceslcsh:Biology (General)lcsh:QD1-999Synthetic ReceptorsQuantum TheorySupramolecular chemistryInternational Journal of Molecular Sciences
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Accurate Treatment of Large Supramolecular Complexes by Double-Hybrid Density Functionals Coupled with Nonlocal van der Waals Corrections.

2015

In this work, we present a thorough assessment of the performance of some representative double-hybrid density functionals (revPBE0-DH-NL and B2PLYP-NL) as well as their parent hybrid and GGA counterparts, in combination with the most modern version of the nonlocal (NL) van der Waals correction to describe very large weakly interacting molecular systems dominated by noncovalent interactions. Prior to the assessment, an accurate and homogeneous set of reference interaction energies was computed for the supramolecular complexes constituting the L7 and S12L data sets by using the novel, precise, and efficient DLPNO-CCSD(T) method at the complete basis set limit (CBS). The correction of the bas…

Models MolecularWork (thermodynamics)Macromolecular SubstancesAccurate treatmentSupramolecular chemistryVan der Waals surfaceDouble-hybrid density functionalsSet (abstract data type)symbols.namesakeLarge supramolecular complexesQuantum mechanicsNon-covalent interactionsComputer SimulationQuímica FísicaLimit (mathematics)Statistical physicsPhysical and Theoretical ChemistryBasis setNonlocal van der Waals correctionschemistry.chemical_classificationChemistryComputer Science ApplicationsModels ChemicalsymbolsQuantum Theoryvan der Waals forceHydrophobic and Hydrophilic InteractionsJournal of chemical theory and computation
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Mean-Field Calculation Based on Proton-Neutron Mixed Energy Density Functionals

2014

We have performed calculations based on the Skyrme energy density functional (EDF) that includes arbitrary mixing between protons and neutrons. In this framework, single-particle states are generalized as mixtures of proton and neutron components. The model assumes that the Skyrme EDF is invariant under the rotation in isospin space and the Coulomb force is the only source of the isospin symmetry breaking. To control the isospin of the system, we employ the isocranking method, which is analogous to the standard cranking approach used for describing high-spin states. Here, we present results of the isocranking calculations performed for the isobaric analog states in $A = 40$ and $A = 54$ nuc…

Nuclear Theory (nucl-th)Nuclear Theoryproton-neutron mixingisobaric analog statesNuclear TheoryFOS: Physical sciencesNuclear Experimentenergy density functionals
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Structure of transactinide nuclei with relativistic energy density functionals

2013

A microscopic theoretical framework based on relativistic energy density functionals (REDFs) is applied to studies of shape evolution, excitation spectra, and decay properties of transactinide nuclei. Axially symmetric and triaxial relativistic Hartree-Bogoliubov (RHB) calculations, based on the functional DD-PC1 and with a separable pairing interaction, are performed for the even-even isotopic chains between Fm and Fl. The occurrence of a deformed shell gap at neutron number $N=162$ and its role on the stability of nuclei in the region around $Z=108$ is investigated. A quadrupole collective Hamiltonian, with parameters determined by self-consistent constrained triaxial RHB calculations, is…

Nuclear and High Energy PhysicsNuclear TheoryTransactinide element01 natural sciencesenergy density functionalsSeparable spacesymbols.namesake0103 physical sciences010306 general physicsPhysicsta114010308 nuclear & particles physicsObservablecollective modelstransactinide nuclei ; energy density functionals ; collective modelsNATURAL SCIENCES. Physics.PRIRODNE ZNANOSTI. Fizika.transactinide nucleiTheoretical nuclear physicsPairingNeutron numberQuadrupolesymbolsAtomic physicsHamiltonian (quantum mechanics)Axial symmetry
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Landau parameters for energy density functionals generated by local finite-range pseudopotentials

2017

In Landau theory of Fermi liquids, the particle-hole interaction near the Fermi energy in different spin-isospin channels is probed in terms of an expansion over the Legendre polynomials. This provides a useful and efficient way to constrain properties of nuclear energy density functionals in symmetric nuclear matter and finite nuclei. In this study, we present general expressions for Landau parameters corresponding to a two-body central local regularized pseudopotential. We also show results obtained for two recently adjusted NLO and N$^2$LO parametrizations. Such pseudopotentials will be used to determine mean-field and beyond-mean-field properties of paired nuclei across the entire nucle…

Nuclear and High Energy PhysicsNuclear Theory[PHYS.NUCL]Physics [physics]/Nuclear Theory [nucl-th]HARTREE-FOCK CALCULATIONSNuclear Theoryregularized pseudopotentialsFOS: Physical sciencesFinite range114 Physical sciences7. Clean energy01 natural sciencesenergy density functionalsNuclear Theory (nucl-th)PseudopotentialLandau parametersQuantum mechanics0103 physical sciencesNuclear Experiment010306 general physicsLegendre polynomialsNUCLEAR-MATTERPhysics010308 nuclear & particles physicsFermi energyNuclear matterLandau theoryEnergy densityFermi Gamma-ray Space TelescopeJournal of Physics G: Nuclear and Particle Physics
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Nonlocal energy density functionals for pairing and beyond-mean-field calculations

2017

We propose to use two-body regularized finite-range pseudopotential to generate nuclear energy density functional (EDF) in both particle-hole and particle-particle channels, which makes it free from self-interaction and self-pairing, and also free from singularities when used beyond mean field. We derive a sequence of pseudopotentials regularized up to next-to-leading order (NLO) and next-to-next-to-leading order (N2LO), which fairly well describe infinite-nuclear-matter properties and finite open-shell paired and/or deformed nuclei. Since pure two-body pseudopotentials cannot generate sufficiently large effective mass, the obtained solutions constitute a preliminary step towards future imp…

Nuclear and High Energy PhysicsNuclear Theory[PHYS.NUCL]Physics [physics]/Nuclear Theory [nucl-th]regularized pseudopotentialsFOS: Physical sciences114 Physical sciences01 natural sciences7. Clean energyenergy density functionalsPseudopotentialNuclear Theory (nucl-th)Effective mass (solid-state physics)0103 physical sciencesEQUATIONStatistical physics010306 general physicsPhysicsNUCLEIEnergy density functional010308 nuclear & particles physicsMean field theoryPairingEnergy densitynuclear pairingGravitational singularityFORCES
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Properties of nuclei in the nobelium region studied within the covariant, Skyrme, and Gogny energy density functionals

2015

We calculate properties of the ground and excited states of nuclei in the nobelium region for proton and neutron numbers of 92 <= Z <= 104 and 144 <= N <= 156, respectively. We use three different energy-density-functional (EDF) approaches, based on covariant, Skyrme, and Gogny functionals, each within two different parameter sets. A comparative analysis of the results obtained for odd-even mass staggerings, quasiparticle spectra, and moments of inertia allows us to identify single-particle and shell effects that are characteristic to these different models and to illustrate possible systematic uncertainties related to using the EDF modelling

Nuclear and High Energy Physics[PHYS.NUCL]Physics [physics]/Nuclear Theory [nucl-th]ProtonNuclear TheoryNuclear Theorychemistry.chemical_elementFOS: Physical sciences7. Clean energySpectral lineMoments of inertiaNuclear physicsNuclear Theory (nucl-th)NeutronCovariant transformationHeavy and superheavy nucleiPhysicsta114Odd–even mass staggeringMoment of inertiachemistryExcited stateQuasiparticleNobeliumQuasiparticle excitationsNuclear energy density functionalsNuclear masses
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Helmholtz equation in unbounded domains: some convergence results for a constrained optimization problem

2016

We consider a constrained optimization problem arising from the study of the Helmholtz equation in unbounded domains. The optimization problem provides an approximation of the solution in a bounded computational domain. In this paper we prove some estimates on the rate of convergence to the exact solution.

Optimization problemHelmholtz equationDomain (software engineering)Constrained optimization problemExact solutions in general relativityMathematics - Analysis of PDEsRate of convergenceBounded functionConvergence (routing)FOS: MathematicsHelmholtz equation Transparent boundary conditions Minimization of integral functionals.Applied mathematicsMathematicsAnalysis of PDEs (math.AP)
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First-Principles Study on Polymorphs of AgVO3: Assessing to Structural Stabilities and Pressure-Induced Transitions

2017

In this paper, we present a comprehensive theoretical study, based on density-functional theory calculations, and which focuses on the structural and electronic properties of silver vanadium oxide (AgVO3) in the monoclinic [Cm (β-AgVO3), C2/c (α-AgVO3), and Cc], orthorhombic (Amm2), and cubic (Pm3̅m) phases from 0–30 GPa. The structural and electronic properties, the stability of different phases, and the pressure-induced solid–solid phase transitions of AgVO3 have been previously studied. The effects of pressure on the band structures, energy–gap values, density of states, and vibrational frequencies are also studied. Numerical and analytical calculations are conducted to obtain the lattic…

Phase transitionpressure-induced transitionsThermodynamics02 engineering and technology010402 general chemistry01 natural sciencesVanadium oxidesolid-solid phase transitionsLattice (order)silverPhysical and Theoretical Chemistrystructural propertiesBulk modulussilver compoundsChemistry021001 nanoscience & nanotechnology0104 chemical sciencesSurfaces Coatings and FilmsElectronic Optical and Magnetic MaterialsCrystallographyGeneral Energyexchange-correlation functionalsDensity of statesOrthorhombic crystal system0210 nano-technologyPressure derivativeMonoclinic crystal system
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