Search results for "Facteur"
showing 10 items of 73 documents
Dépôts carbonatés microbiens en domaine lacustre et fluviatile : fabriques et facteurs de contrôle
2020
The non-marine carbonates related to microbial activity display a large range of morphologies and compositions and accumulate in various settings (freshwater, alkaline, and saline lakes, fluvial environments, thermal and freshwater springs, …). The variety of non-marine microbial carbonates and their particularity led to propose numerous and complex terminologies and classifications, making their use complicated and restrictive for the interpretation of depositional settings. Mineralization of these carbonates results from the interaction between biotic factors (intrinsic) and environmental factors (extrinsic and external) at multi-scales. The first aim of this work was to characterize morp…
Doit-on sélectionner ou former les élites scolaires ? Une comparaison internationale des politiques éducatives
2005
This article aims to provide a starting point for reflection about the conditions required for building up an academic elite in mandatory school systems, through international quantitative evaluation.The academic elite are defined, here, not in terms of the educational level they have reached, but through the skills levels attained: the proportion of students who have reached, in each country, the highest level of skill on the main section of the PISA 2000 test. After setting out the theoretical framework, it provides analysis showing that amongst the societal factors, once a certain level of economic development has been exceeded, the size of the academic elite population is much more a fu…
The Influence of Strategic and Organizational Factors as Concern the Relationship between Environmental Management Control and Organizational Learnin…
2020
This article examines the relationship between Environmental Management Control (EMC) and Organizational Learning (OL) by extending the theoretical model of Simons (1995) in a contingent perspective. Through strategic and organizational factors, this enriched model expounds the links between the Simons’s (1995) levers of control (diagnostic and interactive controls) and the Argyris and Schön’s (1978) levels of learning (simple loop learning and double loop learning). Based on the “revelatory case” of a missionary organization, eco-SME, this study highlights the influence of three contingency factors : strong core values, proactive strategy and activity life cycle in the four configurations …
Influence des facteurs socio-économiques et géographiques sur l'incidence, l'accès aux soins et la survie des femmes atteintes d'un cancer du sein
2012
In developed countries, breast cancer is currently the leading cancer in women in terms of incidence and mortality (standardized rate of 101.5 and 17.7 per 100,000 person-years in 2005, respectively). Many risk factors and prognostic factors have been studied and are well known. Research is under way with regard to every step in the development of breast cancer, but the impact of socio-economic and geographic factors, at the individual and environmental level with regard to the disease have never been studied in France.The general aim of this work was to explore the impact of these factors in different ways to build on our knowledge and to develop practical applications in the primary, seco…
Etude du rôle du monoxyde d’azote (NO) dans la réponse du transcriptome d’Arabidopsis thaliana aux oligogalacturonides, un éliciteur des réactions de…
2012
SPEIPM; International audience; Le monoxyde d’azote (NO) est capable de réguler chez les plantes de nombreux processus physiologiques dont les réponses des plantes aux pathogènes. Peu d’informations sont disponibles aujourd’hui sur les mécanismes expliquant le rôle du NO endogène dans ce contexte physiologique. Grâce à une étude transcriptomique, nous avons caractérisé chez Arabidopsis thaliana, des gènes cibles du NO produit en réponse à un éliciteur des réactions de défense, les oligogalacturonides (OG). L’analyse a permis d’identifier parmi ces gènes cibles, un nombre important de gènes impliqués dans les réponses aux stress biotiques tels que des facteurs de transcription ou des protéin…
Addressing and control of optical nanosources by integrated or fibered plasmonics
2015
Surface plasmon polariton (SPP) can confine light on subwavelength dimensions. Since they are not diffraction limited, they are of great interest for addressing and controlling optical nanosources. For example, a metal nanowire defines 1D plasmonic waveguide with a great potential for either addressing or coupling quantum emitters. Therefore, SPP opens great opportunities for integrated optical applications. However, SPP suffer from ohmic losses that jeopardize the applications of plasmonic components. In this context, we study the possibilities provided by an hybrid plasmonic-photonicstructure to couple efficiently an emitter to a fiber mode. Such a structure paves the way for fibered sing…
Myxoma virus Leukemia-associated protein is responsible for major histocompatibility complex class I and Fas-CD95 down-regulation and defines scrapin…
2002
ABSTRACTDown-modulation of major histocompatibility class I (MHC-I) molecules is a viral strategy for survival in the host.Myxoma virus, a member of thePoxviridaefamily responsible for rabbit myxomatosis, can down-modulate the expression of MHC-I molecules, but the viral factor(s) has not been described. We cloned and characterized a gene coding for an endoplasmic reticulum (ER)-resident protein containing an atypical zinc finger and two transmembrane domains, which we called myxoma virus leukemia-associated protein (MV-LAP). MV-LAP down-regulated surface MHC-I and Fas-CD95 molecules upon transfection; the mechanism probably involves an exacerbation of endocytosis and was lost when the ER r…
Dissecting the factors controlling seed development in the model legume Medicago truncatula
2012
Legumes are not only indispensible for sustainable agriculture but are also a rich source of protein in food and feed for humans and animals, respectively. However, major proteins stored in legume seeds are poor in sulfur-containing amino acids, and may be accompanied by anti-nutritional factors causing low protein digestibility problems. In this regard, Medicago truncatula serves as a model legume to study legume seed development especially the phase of seed storage protein accumulation. As developing legume seeds are complex structures, a thorough knowledge of the morphogenesis of the seed and the characterization of regulatory mechanisms underlying the embryo development and seed filling…
Étude de la collaboration interprofessionnelle dans le secteur hospitalier français : le rôle des facteurs organisationnels
2022
In a troubled hospital context subject to many changes and constraints, inter-professional collaboration is a major asset in terms of adaptation, quality of care and managerial innovation. However, its levers remain to be specified and its implementation is complex. A review of the literature and an empirical survey lay the foundation for our research work, which has various objectives. First of all, it seeks to clarify the place of interprofessional collaboration in the hospital sector. Then he seeks to understand the influence of organizational factors on emerging states of collaboration. Finally, it examines how health managers can rely on organizational factors to enable the emergence o…
Étude de la régulation transcriptionnelle des lymphocytes Th9
2017
CD4 helper T cells support a wide range of functions due to their ability to differentiate into different effector subsets depending on the antigen encountered and the cytokine environment in which they are. Current knowledge on the differentiation of helper T cells highlights the existence of complex transcriptional networks specific to each T helper subset. In 2008, IL-9 secreting CD4 T cells (Th9) are identified as a new helper T cell subtype. Differentiated in the presence of IL-4 and TGF-β, Th9 cells secrete IL-9 and IL-21, and contribute to the development of autoimmune and allergic diseases. Th9 lymphocytes also exhibit strong anti-tumor properties.The transcriptional network of the …