Search results for "Factorial"
showing 10 items of 253 documents
Polygenic Risk Scores and Physical Activity
2020
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The Molecular Genetic Architecture of Self-Employment
2013
Economic variables such as income, education, and occupation are known to affect mortality and morbidity, such as cardiovascular disease, and have also been shown to be partly heritable. However, very little is known about which genes influence economic variables, although these genes may have both a direct and an indirect effect on health. We report results from the first large-scale collaboration that studies the molecular genetic architecture of an economic variable-entrepreneurship-that was operationalized using self-employment, a widely-available proxy. Our results suggest that common SNPs when considered jointly explain about half of the narrow-sense heritability of self-employment es…
Researching Parental Socialization Styles across Three Cultural Contexts: Scale ESPA29 Bi-Dimensional Validity in Spain, Portugal, and Brazil
2019
Recent research that relates parenting with adolescent adjustment has shown the importance of considering the cultural context of the relationship. New results are emerging when considering the classical four-typologies model of parental socialization in some European and South-American countries. Among the instruments used in this emergent research is the Parental Socialization Scale ESPA29. This scale is a bi-dimensional parenting instrument that was specifically developed to measure the four parenting typologies, through the dimensions of acceptance/involvement and strictness/imposition. This study examines the good fit of the orthogonal bi-factor model based on the ESPA29 versus one-dim…
Factorial validity of the Maslach Burnout Inventory (MBI-HSS) among Spanish professionals
2005
OBJECTIVE: To assess the factorial validity and internal consistency of the Maslach Burnout Inventory (MBI-HSS). METHODS: In a sample consisting of 705 Spanish professionals from diverse occupational sectors (health, education, police and so one), seven plausible factorial models hypothesized were compared using LISREL 8. RESULTS: The four-factor oblique solution and the three-factor oblique solution showed the best and similar fit. Deletion of Item 12 and Item 16, taking into consideration the suggestions in the manual, improved the goodness of fit for both models. The four-factor oblique model suggests that, in addition to Emotional Exhaustion (EE) and Depersonalization (DP), Personal Acc…
Impact of psychosocial factors on cardiovascular morbimortality: a prospective cohort study
2014
[Background] Whilst it is well known that psychosocial determinants may contribute to cardiovascular diseases (CVD), data from specific groups are scarce. The present study aims to determine the contribution of psychosocial determinants in increasing the risk of cardiovascular events (myocardial infarction and stroke), and death from CVD, in a high risk adult population.
Mercury exposure and risk of cardiovascular disease: a nested case-control study in the PREDIMED (PREvention with MEDiterranean Diet) study
2017
Background: Substantial evidence suggests that consuming 1-2 servings of fish per week, particularly oily fish (e.g., salmon, herring, sardines) is beneficial for cardiovascular health due to its high n-3 polyunsaturated fatty acid content. However, there is some concern that the mercury content in fish may increase cardiovascular disease risk, but this relationship remains unclear. Methods: The PREDIMED trial included 7477 participants who were at high risk for cardiovascular disease at baseline. In this study, we evaluated associations between mercury exposure, fish consumption and cardiovascular disease. We randomly selected 147 of the 288 cases diagnosed with cardiovascular disease duri…
Women and peripheral arterial disease: same disease, different issues
2008
Objectives Atherosclerosis is a multifactorial disease and, thus, its clinical manifestations are likely to present gender-specific differences with respect to their development, course, symptom complexes and prognosis. The present study aimed to examine sex differences in peripheral arterial disease (PAD) and its clinical correlates. Methods PAD severity, quality of life (assessed by ST-22), cardiovascular risk factors, inflammatory profile and comorbidity were assessed in 163 men and 68 women who were consecutively diagnosed with PAD at three Italian University vascular centres. Results Compared to men, women showed a higher prevalence of critical limb ischemia (P = 0.018), but had a less…
Strategies to change body composition in older adults: do type of exercise and dose distribution matter?
2020
Background: This study aims to analyze changes in sedentary elderlies' body composition, comparing the impact of two dose distributions: continuous (60 min/session) vs. accumulated (30 min/session in the morning and 30 min/session in the afternoon), on two types of physical exercise programs (multicomponent-training [MCT] vs. walking interval-training [WIT]). Methods: Forty-six sedentary overweight elderly (71.3±4.3 years) were evaluated by bioimpedance with a pre-post 2x2 factorial design. Participants were distributed in four homogeneous groups, considering gait and health parameters. Results: The overall sample showed significant improvements in fat mass (% and kg) and fat-free mass (kg)…
Blood pressure values and depression in hypertensive individuals at high cardiovascular risk
2014
Background: Hypertension and depression are both important risk factors for cardiovascular diseases. Nevertheless, the association of blood pressure on and depression has not been completely established. This study aims to analyze whether depression may influence the control of blood pressure in hypertensive individuals at high cardiovascular risk. Methods: Cross-sectional study, embedded within the PREDIMED clinical trial, of 5954 hypertensive patients with high cardiovascular risk factor profiles. The relationship between blood pressure control and depression was analyzed. A multivariate analysis (logistic and log-linear regression), adjusting for potential confounders (socio-demographic …
Global variation in anastomosis and end colostomy formation following left-sided colorectal resection
2019
Background: End colostomy rates following colorectal resection vary across institutions in high-income settings, being influenced by patient, disease, surgeon and system factors. This study aimed to assess global variation in end colostomy rates after left-sided colorectal resection. Methods: This study comprised an analysis of GlobalSurg-1 and -2 international, prospective, observational cohort studies (2014, 2016), including consecutive adult patients undergoing elective or emergency left-sided colorectal resection within discrete 2-week windows. Countries were grouped into high-, middle- and low-income tertiles according to the United Nations Human Development Index (HDI). Factors associ…