Search results for "Fatigue"
showing 10 items of 651 documents
NUMERICAL-EXPERIMENTAL METHOD FOR THE ANALYSIS OF RESIDUAL STRESSES IN COLD-EXPANDED HOLES
2012
Hole cold expansion is a technique widely used to improve the fatigue life of components with holes, e.g. bolted or riveted joints. As it has been demonstrated in literature by analytical, numerical and experimental analyses carried out by several authors, the compressive residual stresses introduced by the hole cold expansion have a beneficial influence on both the static and the fatigue strength of the treated component, because they reduce significantly the typical stress peaks around the hole due to stress concentration. In the literature, various analyses of the residual stresses introduced by the hole cold expansion have been performed by using several methods such as X-ray diffractio…
Outlier analysis and principal component analysis to detect fatigue cracks in waveguides
2009
Ultrasonic Guided Waves (UGWs) are a useful tool in structural health monitoring (SHM) applications that can benefit from built-in transduction, moderately large inspection ranges and high sensitivity to small flaws. This paper describes a SHM method based on UGWs, discrete wavelet transform (DWT), outlier analysis and principal component analysis (PCA) able to detect and quantify the onset and propagation of fatigue cracks in structural waveguides. The method combines the advantages of guided wave signals processed through the DWT with the outcomes of selecting defectsensitive features to perform a multivariate diagnosis of damage. The framework presented in this paper is applied to the de…
Application of principal component analysis and wavelet transform to fatigue crack detection in waveguides
2010
Ultrasonic Guided Waves (UGWs) are a useful tool in structural health monitoring (SHM) applications that can benefit from built-in transduction, moderately large inspection ranges and high sensitivity to small flaws. This paper describes a SHM method based on UGWs, discrete wavelet transform (DWT), and principal component analysis (PCA) able to detect and quantify the onset and propagation of fatigue cracks in structural waveguides. The method combines the advantages of guided wave signals processed through the DWT with the outcomes of selecting defect-sensitive features to perform a multivariate diagnosis of damage. This diagnosis is based on the PCA. The framework presented in this paper …
Network Entropy for the Sequence Analysis of Functional Connectivity Graphs of the Brain
2018
Dynamic representation of functional brain networks involved in the sequence analysis of functional connectivity graphs of the brain (FCGB) gains advances in uncovering evolved interaction mechanisms. However, most of the networks, even the event-related ones, are highly heterogeneous due to spurious interactions, which bring challenges to revealing the change patterns of interactive information in the complex dynamic process. In this paper, we propose a network entropy (NE) method to measure connectivity uncertainty of FCGB sequences to alleviate the spurious interaction problem in dynamic network analysis to realize associations with different events during a complex cognitive task. The p…
Production of innovative, recycled and high-performance asphalt for road pavements
2010
Abstract The paper deals with a specific laboratory study aiming at perfectioning recycled asphalt with high mechanical performance, for surface and structural layers of flexible pavements. The aim of the research was to combine in the same material the maximum possible quantity of recycled asphalt (RA), coming from degraded asphalt layers, together with high structural performance of the recycled mixtures obtained (mainly stability, load spreading properties, rutting and fatigue resistance) that should not be lower, or possibly better than those offered by traditional asphalt mixture, made with virgin binder and aggregate. For this purpose, innovative recycled mixtures, close-graded and wi…
QUANTIFICATION OF MUSCLE FATIGUE WITHWAVELET ANALYSIS BASED ON EMG DURING MYOELECTRICAL STIMULATION
2012
6; International audience; We propose a device dedicated to real time analysis of electromyograms (EMG) under myoelectrical stimulation (ES). The muscular fatigue analysis, which is obtained by the use of a dedicated analog circuit and a processing part, is the main purpose of this study. The description of a hardware device which incorporates an electro-stimulator and an electromyogram amplifier combined to a computer is detailed. Then, we present a muscular fatigue analysis part based on wavelet decomposition in order to extract a fatigue index, which is confronted with synthetic and experimental data. We conclude that the CWT index applies well to M waves. The noise sensitivity is invest…
Optimisation d'un électromyostimulateur intelligent pour le reconditionnement musculaire
2017
This project aims to optimize smart electromyostimulators for the muscular reeducation. The electrostimulator optimization aims to improve the electrostimulation sessions (EMS) by obtaining informations on the muscular electical stimulations and the control application in real time in order to control the muscular response. Various control methods of the muscular force are been developed and applied on an accurate model. In first, the techniques will be applied on the partial model without taking into account the muscular fatigue then in second in taking into account the presence of fatigue and its effects. Theses control methods act on the stimulation parameters in frequency and in amplitu…
Adverse events associated with encorafenib plus binimetinib in the COLUMBUS study: incidence, course and management.
2019
Abstract Background Dual inhibition of the mitogen-activated protein kinase pathway with BRAF/MEK inhibitor (BRAFi/MEKi) therapy is a standard treatment for BRAFV600-mutant metastatic melanoma and has historically been associated with grade III pyrexia or photosensitivity depending on the combination used. The objective of this study was to fully describe adverse events from the COLUMBUS study evaluating the most recent BRAF/MEK inhibitor combination encorafenib+binimetinib. Patients and methods Patients with locally advanced, unresectable or metastatic BRAFV600-mutant melanoma were randomised to receive encorafenib 450 mg once daily plus binimetinib 45 mg twice daily, encorafenib 300 mg on…
Neuromuscular junction disassembly and muscle fatigue in mice lacking neurotrophin-4
2001
Neurotrophin-4 (NT-4) is produced by slow muscle fibers in an activity-dependent manner and promotes growth and remodeling of adult motorneuron innervation. However, both muscle fibers and motor neurons express NT-4 receptors, suggesting bidirectional NT-4 signaling at the neuromuscular junction. Mice lacking NT-4 displayed enlarged and fragmented neuromuscular junctions with disassembled postsynaptic acetylcholine receptor (AChR) clusters, reduced AChR binding, and acetylcholinesterase activity. Electromyographic responses, posttetanic potentiation, and action potential amplitude were also significantly reduced in muscle fibers from NT-4 knock-out mice. Slow-twitch soleus muscles from thes…
A thermodynamically consistent CZM for low-cycle fatigue analysis
2018
A cohesive zone model for low-cycle fatigue analysis is developed in a consistent thermodynamic framework of elastic-plastic-damage mechanics with internal variable. A specific fatigue activation condition allows to model the material degradation related to the elastic-plastic cyclic loading conditions, with tractions levels lower than the damage activation condition. A moving endurance surface, in the classic framework of kinematic hardening, enables a pure elastic behavior without any fatigue degradation for low levels loading conditions.