Search results for "Fear"

showing 10 items of 273 documents

Increased sensitivity of the neuronal nicotinic receptor alpha-2 subunit causes familial epilepsy with nocturnal wandering and ictal fear

2006

Sleep has traditionally been recognized as a precipitating factor for some forms of epilepsy, although differential diagnosis between some seizure types and parasomnias may be difficult. Autosomal dominant frontal lobe epilepsy is characterized by nocturnal seizures with hyperkinetic automatisms and poorly organized stereotyped movements and has been associated with mutations of the α4 and β2 subunits of the neuronal nicotinic acetylcholine receptor. We performed a clinical and molecular genetic study of a large pedigree segregating sleep-related epilepsy in which seizures are associated with fear sensation, tongue movements, and nocturnal wandering, closely resembling nightmares and sleep …

AdultMalemedicine.medical_specialtyAdolescentSomnambulismMolecular Sequence DataMutation MissenseAutosomal dominant nocturnal frontal lobe epilepsyReceptors NicotinicBiologymedicine.disease_causeLigandsNicotinicArticleEpilepsyBIO/09 - FISIOLOGIAInternal medicineAcetylcholine; Adolescent; Adult; Aged; Aged 80 and over; Amino Acid Sequence; Epilepsy; Female; Humans; Ligands; Male; Molecular Sequence Data; Mutation Missense; Neurons; Pedigree; Receptors Nicotinic; Somnambulism; FearReceptorsmedicine80 and overGeneticsHumansIctalGenetics(clinical)Amino Acid SequenceGenetics (clinical)Acetylcholine receptorAgedAged 80 and overNeuronsMutationEpilepsySeizure typesFearmedicine.diseaseAcetylcholinePedigreeNicotinic acetylcholine receptorNicotinic agonistEndocrinologyMutationnAChR patch-clamp ADNFLE sleep-related epilepsy M1 TM1 ACh nicotineSettore MED/26 - NeurologiaFemaleMissense
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Anxiety sensitivity as predictor of pain in patients undergoing restorative dental procedures

2006

Abstract –  Objectives:  The personality disposition to anxiety sensitivity refers to beliefs about negative consequences of bodily arousal. The concept has recently been successfully applied in research on chronic pain conditions. The present study investigated whether anxiety sensitivity interacts with dental fear to increase expected and experienced pain during routine dental treatment. Methods:  Subjects were 97 patients undergoing dental procedures of excavation and filling. Anxiety dispositions were measured by the Anxiety Sensitivity Index and the Dental Anxiety Scale. Expected and experienced pain were assessed by affective and sensory verbal descriptor scales and a numerical rating…

AdultMalemedicine.medical_specialtyAdolescentmedia_common.quotation_subjectSensationPainDental fearAnxietyArousalRating scaleDental AnxietyHumansMedicinePersonalityDental Restoration PermanentPsychiatryGeneral DentistryAgedPain Measurementmedia_commonbusiness.industryPublic Health Environmental and Occupational HealthChronic painMiddle Agedmedicine.diseaseAffectstomatognathic diseasesAnxiety sensitivityAnxietyFemalePain catastrophizingmedicine.symptomArousalDental Cavity PreparationbusinessAttitude to HealthForecastingPersonalityClinical psychologyCommunity Dentistry and Oral Epidemiology
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Effects of instruction on acquisition and extinction of electrodermal responses to fear-relevant stimuli.

1977

In the present study we examined the hypothesis that electrodermal responses conditioned to fear-relevant stimuli are insensitive to verbal instructions. In the first experiment, different groups of subjects were conditioned to fear-relevant and fear-irrelevant control stimuli in a long interstimulus interval differential paradigm with shock as the unconditioned stimulus. Then half of the subjects were informed that no more shocks would be presented, and a number of extinction trials followed. The instruction completely abolished responding to fear-irrelevant stimuli, while leaving responses to the fear-relevant stimuli unaffected. In the second experiment, subjects were "conditioned" to fe…

AdultMalemedicine.medical_specialtyAudiologyUnconditioned stimulusExtinction PsychologicalConditioning PsychologicalmedicineHumansElectroshockPhobiasInterstimulus intervalClassical conditioningExperimental InstructionsFearGalvanic Skin ResponseGeneral MedicineExtinction (psychology)Middle Agedmedicine.diseasePsychophysiologyPhobic DisordersVisual PerceptionConditioning OperantFemaleSkin conductancePsychologyCognitive psychologyJournal of Experimental Psychology: Human Learning and Memory
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Detection and distraction effects for threatening information in social phobia and change after treatment.

2007

This work examines differences in the detection and distraction by social-threatrelated information between a social phobia group (SP; N533) and a normal control group (NC; N532). The change obtained after psychological treatment is also studied for the SP group. A paper-and-pencil visual search task is used, in which the emotional valence of the ‘‘target’’ (social threat, physical threat, and neutral words) and ‘‘distractor’’ (social threat, physical threat, neutral, and nonsense words) verbal stimuli is manipulated. Results indicate that there are no differences in the detection of social-threat targets between SP and NC participants. However, the performance of SP individuals is more imp…

AdultMalemedicine.medical_specialtyEmotionsAttentional biasAudiologybehavioral disciplines and activitiesDevelopmental psychologyAntropofòbiaDistractionmedicineReaction TimeHumansAttentionValence (psychology)Psychological treatmentVisual searchPsicologia clínicaAttentional biasCognitive Behavioral TherapyVisual searchVerbal BehaviorFearControl GroupsPsychiatry and Mental healthClinical PsychologyPsicobiologiaPhobic DisordersSocial PerceptionVisual PerceptionAnxietyFemaleSocial threatDistractibilitymedicine.symptomCuesPsychologySocial phobiaArousalAfter treatmentFollow-Up StudiesDepression and anxiety
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Focus group study to identify the central facets of fear of hypoglycaemia in people with Type 2 diabetes mellitus.

2017

Aims To determine key worries about hypoglycaemia among insulin-using adults with Type 2 diabetes using a focus group approach. Methods Thirteen focus groups were conducted in three diabetes outpatient care units and one peer support group was set up, in Germany. A total of 64 insulin-dependent adults with Type 2 diabetes (36.5% women, mean age 65.2 ± 11.0 years) discussed their worries about hypoglycaemia. The qualitative results were assigned into thematic categories using a bottom-up coding procedure. Participants completed the Hypoglycaemia Fear Survey and demographic measures were recorded. The results of the Hypoglycaemia Fear Survey were contrasted with the focus group findings to ev…

AdultMalemedicine.medical_specialtyEndocrinology Diabetes and Metabolismmedia_common.quotation_subject030209 endocrinology & metabolismType 2 diabetesPeer support03 medical and health sciences0302 clinical medicineEndocrinologyQuality of lifeAmbulatory careDiabetes mellitusGermanyInternal MedicinemedicineHumansHypoglycemic Agents030212 general & internal medicinePsychiatrymedia_commonAgedbusiness.industryType 2 Diabetes MellitusFearAwarenessFocus GroupsMiddle Agedmedicine.diseaseFocus groupHypoglycemiaSelf EfficacyDiabetes Mellitus Type 2Socioeconomic FactorsQuality of LifeFemaleWorrybusinessDiabetic medicine : a journal of the British Diabetic Association
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The cardiac anxiety syndrome ? a subtype of panic attacks

1985

Cardiac anxiety syndrome and the diagnosis of cardiac neurosis respectively are characterized by panic attacks. Panic attacks are the core syndrome of a validated anxiety disorder (panic disorder). The purpose of this study was to investigate if the cardiac anxiety syndrome represents a separate disorder or if it is only a subtype of panic attacks. In a sample of 122 patients with panic attacks, all patients with a cardiac anxiety syndrome were selected (n = 31). Furthermore, parallel to this group--matched in the variables age and sex--a second group of patients with no cardiac anxiety syndrome was selected. There were no significant differences in course; in clinical phenomenology, patien…

AdultMalemedicine.medical_specialtyNeurosisPhobic avoidancebehavioral disciplines and activitiesManuals as TopicInternal medicinemental disordersmedicineHumansPharmacology (medical)Biological PsychiatryDepression (differential diagnoses)Neurocirculatory AstheniaPsychiatric Status Rating ScalesDepressive Disorderbusiness.industryGeneral NeurosciencePanic disorderPanicFearGeneral Medicinemedicine.diseasePanicPsychiatry and Mental healthNeuropsychology and Physiological PsychologyPhobic DisordersChronic Diseasecardiovascular systemAnxietyFemalemedicine.symptombusinessSomatizationAnxiety disorderClinical psychologyEuropean Archives of Psychiatry and Neurological Sciences
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One-year follow-up of cardiac anxiety syndromes. Outcome and predictors of course.

1987

In a representative sample (n = 31) of patients with panic attacks and a cardiac anxiety syndrome, a prospective follow-up study after a 1-year interval was performed. At the follow-up assessment 33% of the patients were in remission, whereas the majority of patients had an unfavorable course. Avoidance behavior and female sexual status were found to be predictive for an unfavorable course. Within a matched-pair design controlled for age and sex, no difference between panic disorder with and without cardiac anxiety syndrome was observed in any psychosocial or psychopathological outcome variable. This result is an argument against the validity of the subtype cardiac anxiety syndrome.

AdultMalemedicine.medical_specialtyPediatricsSex FactorsmedicineAvoidance LearningHumansPharmacology (medical)PsychiatryBiological PsychiatryDepression (differential diagnoses)General NeurosciencePanic disorderPanicHeartGeneral MedicineFearSemiologymedicine.diseasePrognosisAnxiety DisordersPanicOutcome (probability)Psychiatry and Mental healthNeuropsychology and Physiological PsychologyAnxietyFemalemedicine.symptomPsychologyPsychosocialPsychopathologyFollow-Up StudiesEuropean archives of psychiatry and neurological sciences
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One-year follow-up of panic disorder. Outcome and prognostic factors.

1988

A 1-year follow-up study was carried out in 77 patients with panic attacks (panic disorder). Of these patients 43% were remitted; avoidance behaviour and chronic anxiety were more persistent than panic attacks within the 1-year period. The main predictor for features of anxiety in the follow-up was avoidance behaviour. The most prominent prognostic factor for features of depression was the history of previous depressive episodes. Female patients had a poorer outcome than male patients.

AdultMalemedicine.medical_specialtyPrognostic factorOne year follow upChronic anxietybehavioral disciplines and activitiesSex Factorsmental disordersFemale patientmedicineHumansPsychiatryDepression (differential diagnoses)Depressive DisorderGeneral NeurosciencePanic disorderPanicFearmedicine.diseasePrognosisAnxiety DisordersPanicAntidepressive AgentsHospitalizationPsychotherapyPsychiatry and Mental healthNeuropsychology and Physiological PsychologyOutcome and Process Assessment Health CareAnti-Anxiety AgentsChronic DiseaseAnxietyFemalemedicine.symptomPsychologyFollow-Up StudiesEuropean archives of psychiatry and neurological sciences
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Psychometric Properties and factor structure of the spanish version of the HC-PAIRS questionnaire

2012

Objective To develop a Spanish version of the Health Care Providers" Pain and Impairment Relationship Scale (HC-PAIRS) and to test its psychometric properties. Methods A forward and backward translation methodology was used to translate the questionnaire, which was then applied to 206 participants (174physiotherapy students and 32 family physicians). The intraclass correlation coefficient was calculated to assess testretest reliability. Internal consistency was evaluated using Cronbach"s alpha and item analysis. Construct validity was measured using Pearson correlation coefficients between HC-PAIRS and FABQ, FABQ-Phys, FABQ-Work and the responses given by participants to three clinical case…

AdultMalemedicine.medical_specialtyPsychometricsPsychometricsAttitude of Health PersonnelFactor structureSensitivity and SpecificityInternal consistencySurveys and QuestionnairesHealth caremedicineHumansOrthopedics and Sports MedicineTranslationsPsychiatrySalut mentalPain Measurementbusiness.industryReproducibility of ResultsSpanish versionFearMiddle AgedTest (assessment)SpainSurgeryOriginal ArticleFemalebusinessFactor Analysis StatisticalLow Back Pain
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Finnish version of the Tampa Scale of Kinesiophobia: Reference values in the Finnish general population and associations with leisure-time physical a…

2014

[Abstract.] Objectives: To create reference values for the general Finnish population using the Tampa Scale of Kinesiophobia (TSK-FIN), to study gender differences in the TSK-FIN, to assess the internal consistency of the TSK-FIN, to estimate the prevalence of high levels of kinesiophobia in Finnish men and women, and to examine the association between kinesio-phobia and leisure-time physical activity and the impact of co-morbidities on kinesiophobia. Methods: The study population comprised 455 men and 579 women. Participants completed a self-administered questionnaire about their socio-demographic factors, leisure-time physical activity, co-morbidities and kinesiophobia. Results: The mean …

AdultMalemedicine.medical_specialtyPsychometricsPsychometricsPopulationPhysical activityphysical activityPhysical Therapy Sports Therapy and RehabilitationMotor ActivityLeisure ActivitiesCronbach's alphaReference ValuesSurveys and QuestionnairesPrevalencemedicineviitearvotHumansMusculoskeletal DiseaseseducationFinlandPain MeasurementSex Characteristicseducation.field_of_studyRehabilitationFearGeneral MedicineMiddle Agedco-morbiditiesPhobic DisordersReference valuesScale (social sciences)Physical therapyPopulation studyFemalePsychologyLow Back Painpain-related fearSex characteristics
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