Search results for "Fertility"
showing 10 items of 629 documents
Fertility protection: complications of surgery and results of removal and transplantation of ovarian tissue
2017
Fertility-preserving measures are becoming important for patients receiving oncological treatment. One method involves cryopreservation of ovarian tissue and transplanting it when treatment is completed. We report complications resulting from surgical and fertility medicine, and the results of procedures for the removal and transplantation of ovarian tissue carried out within the FertiProtekt network. A survey using a structured questionnaire was conducted among the FertiProtekt network centres between November 2015 and June 2016. The analysis included surgical techniques used to remove and transplant ovarian tissue, surgical complications and results. Laparoscopic removal and transplantati…
Follow-Up and Relook Hysteroscopy
2020
Intra-uterine adhesions (IUAs) after initial treatment in patients with Asherman’s Syndrome are one of the main challenging issues in the gynecological practice, since its incidence has been increasing over the last few decades, with a reported recurrence rate up to 30%. Asherman syndrome is characterized by variable scarring inside the uterine cavity that can lead to partial or complete dysfunction of the endometrium with impairment of fertility and menstrual pattern (amenorrhea and hypomenorrhea).
Descriptive study on subjective experience of genetic testing with respect to relationship, family planning and psychosocial wellbeing among women wi…
2021
AbstractBackgroundDue to increased risk of endometrial and ovarian cancer, women belonging to known Lynch Syndrome (LS) families are recommended to undergo germline testing. Current practice in Finland is to offer counselling to women with pathogenic variant and advocate risk-reducing surgery (RRS) after completion of childbirth. The present study aimed to clarify the impacts of positive germline testing on family planning and reproductive decisions of these women, which are relatively unknown.MethodsSeventy-nine carriers of germline MMR gene pathogenic variant (path_MMR)were identified from the Finnish LS Registry as having genetic testing performed before the age of 45 years and not havin…
Fertility in McCune Albright syndrome female: A case study focusing on AMH as a marker of ovarian dysfunction and a literature review.
2021
Abstract Background The molecular basis of McCune Albright syndrome (MAS) is a recurrent GNAS Postzygotic gain of function sporadic mutation, resulting in a mosaic disease. Most of girls present precocious puberty, caused by the development of recurrent ovarian cysts with autonomous Hyperestrogenic stimulation. After menarche, the majority of patients with ovarian GNAS mutation have menstrual disturbances and infertility. Objectives We wanted to focus on the fertility of MAS females and propose an appropriate management, by a detailed case report and an exhaustive review of the literature on fertility and pregnancy in MAS females. Results We present the case of a 29-year-old MAS female, who…
Model społeczeństwa a założenia Specjalnej Strefy Demograficznej
2016
Założenia opolskiej Specjalnej Strefy Demograficznej odwołują się do strukturalno-systemowych teorii społeczeństwa. Stan katastrofy demograficznej wymaga, moim zdaniem, przeprowadzenia reprezentatywnych badań empirycznych wśród młodego pokolenia, opracowania socjologicznego studium i uzupełnienia teoretycznych założeń Specjalnej Strefy Demograficznej w regionie opolskim.
Rescue of ovarian function: stem cells and regenerative factors
2022
El envejecimiento y otras condiciones de daño adquiridas, como los tratamientos oncológicos, conducen a un deterioro de la función ovárica. Sin embargo, incluso cuando los ovarios dañados pierden su capacidad de ovular, permanece un conjunto residual de folículos quiescentes que podrían ser rescatados y desarrollados en un nicho ovárico adecuado, dando lugar a ovocitos maduros. Los factores solubles secretados por las células madre podrían proporcionar un entorno ovárico adecuado para mantener y promover el crecimiento folicular. Por lo tanto, la presente tesis doctoral tuvo como objetivo evaluar los efectos regenerativos de diferentes fuentes de factores secretados por células madre en mod…
LH administration as a potential strategy for ovarian protection and female fertility preservation against highly gonadotoxic chemotherapy
2022
Els ovaris contenen una reserva de fol·licles no renovable, que produeixen un únic ovòcit fecundable a cada cicle menstrual al llarg de l'etapa reproductiva femenina (15-49 anys), però que disminueix progressivament amb l'edat. Per tant, els factors que afecten negativament la dotació de fol·licles provocaran una reducció significativa de la vida reproductiva en la dona. Les teràpies oncològiques basades en l'administració de quimioteràpia alquilant s'utilitzen habitualment per a tractar els càncers ginecològics en pacients joves, però amb freqüència acceleren l'esgotament de la reserva fol·licular i l'aparició de la menopausa. Els efectes secundaris de la quimioteràpia sobre la fertilitat,…
Prostaglandin E2 and prostaglandin F2 alpha as endometrial receptivity biomarkers in successful embryo implantation
2014
Failure in the adhesion of the human blastocyst to the endometrium has been described as an important cause of infertility. Establishing the period of the so-called window of implantation and understanding the molecular mechanisms associated with embryo implantation has clinical and scientific implications. While over the last decades histological evaluation has been used to determine the phase of the menstrual cycle of the endometrium, the poor information obtained has made the case of using new technologies to identify specific markers, understand and characterize the receptive stage. This doctoral thesis investigates the existence, function and clinical impact of two specific lipids, the…
Effects of Oral Supplementation with Myo-Inositol and D-Chiro-Inositol on Ovarian Functions in Female Long-Term Survivors of Lymphoma: Results from a…
2022
The progressive improvement of lymphoma treatment has led to an important prolongation of patient survival and life expectancy. The principal international scientific societies of oncology now therefore recommend that long-term survivors of lymphoma join fertility programs. Specifically, fertile-age patients should be assisted by a multidisciplinary team, including specialists dedicated to fertility preservation in oncology, in order to support the completion of their reproductive project. In the general population, the use of Myo-Inositol and D-Chiro-Inositol (MI/DCI) has been demonstrated to be an effective choice to treat ovarian dysfunctions, with a consequent improvement in reproductiv…
Is it possible to understand a book missing a quarter of the letters? Unveiling the belowground species richness of grasslands
2022
Abstract Knowledge of species richness patterns in plant communities is biased toward its hidden belowground part and is derived only from the part visible aboveground. Studies on the relationship of the above- to belowground parts of plant communities suffer from the lack of a consistent and uniform approach to assess their taxonomic composition, particularly in species-rich ecosystems. This study described the proportion between above- and belowground parts of vegetation in three grassland types along with the environmental factors that affect them, using eDNA metabarcoding and an observer survey. The internal transcribed spacer 2 (ITS2) region was used to analyze the total plant richness…