Search results for "Fibrillation"

Left Atrial Remodeling and Brain Natriuretic Peptide Levels Variation after Left Atrial Appendage Occlusion

2021

Background: Few data are available about brain natriuretic peptide (BNP) variation and left atrial remodeling after the left atrial appendage occlusion (LAAO) technique. Methods: Prospective study included all consecutive patients successfully implanted with an LAAO device. Contrast-enhanced cardiac computed tomography (CT) was performed before and 6 weeks after the procedure with reverse left atrial remodeling defined by an increase in LA volume &gt

Inversion of Left Atrial Appendage Will Cause Compressive Stresses in the Tissue: Simulation Study of Potential Therapy

2022

In atrial fibrillation (AF), thromboembolic events can result from the particular conformation of the left atrial appendage (LAA) bearing increased clot formation and accumulation. Current therapies to reduce the risk of adverse events rely on surgical exclusion or percutaneous occlusion, each of which has drawbacks limiting application and efficacy. We sought to quantify the hemodynamic and structural loads of a novel potential procedure to partially invert the “dead” LAA space to eliminate the auricle apex where clots develop. A realistic left atrial geometry was first achieved from the heart anatomy of the Living Heart Human Model (LHHM) and then the left atrial appendage inversion (LAAI…

Atrioventricular junction ablation as a bridging treatment of tachycardiomyopathy and renal insufficiency in the course of atrial fibrillation with h…

2019

We present the case of a 67 year-old woman with tachycardiomyopathy induced by atrial fibrillation with high frequency ventricular response. The patient underwent resynchronisation pacemaker implantation and atrioventricular junction ablation as a bridging therapy prior to cryoballoon pulmonary vein ostia ablation.

Effectiveness and safety of electrical cardioversion for acute-onset atrial fibrillation in the emergency department: a real-world 10-year single cen…

2019

OBJECTIVE Despite limited evidence, electrical cardioversion of acute-onset atrial fibrillation (AAF) is widely performed in the emergency department (ED). The aim of this study was to describe the effectiveness and safety of electrical cardioversion of AAF performed by emergency physicians in the ED. METHODS All episodes of AAF electrically cardioverted in the ED were retrieved from the database for a 10-year period. Most patients not already receiving anticoagulants were given enoxaparin before the procedure (259/419). Procedural complications were recorded, and the patients were followed-up for 30 days for cardiovascular and hemorrhagic complications. RESULTS Four hundred nineteen eligib…

Análisis tiempo-frecuencia de la fibrilación ventricular. Estudio experimental

2006

Introduction and objectives. The analysis of frequency variability during ventricular fibrillation has yielded inconsistent results. We used an experimental model of ventricular fibrillation, with a short timescale, to analyze variations in frequency and their associated spatial distribution. Methods. Epicardial recordings of ventricular fibrillation were made in 10 perfused isolated rabbit heart preparations using a multiple electrode system (i.e., 240 unipolar electrodes). Both spectral and time-frequency analysis were used to derive the dominant frequency in the anterolateral wall of the left ventricle. Results. Linear regression analysis showed that there was a good correlation between …

Influencia del tipo de registro (unipolar o bipolar) en las características espectrales de los registros epicárdicos de la fibrilación ventricular. E…

2007

Introduction and objectives. The aim of this study was to examine the hypothesis that the recording mode (ie, unipolar or bipolar) affects the information obtained using spectral analysis techniques during ventricular fibrillation by carrying out an experiment using epicardial electrodes. Methods. Recordings of ventricular fibrillation were obtained in 29 isolated rabbit hearts using a multipleelectrode probe located on the left ventricular free wall. The parameter values obtained in the frequency domain (by Fourier analysis) using unipolar or bipolar electrodes, different interelectrode distances, and different orientations (ie, horizontal, vertical, or diagonal) were compared. Results. Ch…

Public Access Defibrillation

2000

Ventilation/perfusion ratios measured by multiple inert gas elimination during experimental cardiopulmonary resuscitation

2014

Background During cardiopulmonary resuscitation (CPR) the ventilation/perfusion distribution (VA/Q) within the lung is difficult to assess. This experimental study examines the capability of multiple inert gas elimination (MIGET) to determine VA/Q under CPR conditions in a pig model. Methods Twenty-one anaesthetised pigs were randomised to three fractions of inspired oxygen (1.0, 0.7 or 0.21). VA/Q by micropore membrane inlet mass spectrometry-derived MIGET was determined at baseline and during CPR following induction of ventricular fibrillation. Haemodynamics, blood gases, ventilation distribution by electrical impedance tomography and return of spontaneous circulation were assessed. Inter…

Circulating Levels of Ferritin, RDW, PTLs as Predictive Biomarkers of Postoperative Atrial Fibrillation Risk after Cardiac Surgery in Extracorporeal …

2022

Postoperative atrial fibrillation (POAF) is the most common arrhythmia after cardiac surgery in conventional extracorporeal circulation (CECC), with an incidence of 15–50%. The POAF pathophysiology is not known, and no blood biomarkers exist. However, an association between increased ferritin levels and increased AF risk, has been demonstrated. Based on such evidence, here, we evaluated the effectiveness of ferritin and other haematological parameters as POAF risk biomarkers in patients subjected to cardiac surgery. We enrolled 105 patients (mean age = 70.1 ± 7.1 years; 70 men and 35 females) with diverse heart pathologies and who were subjected to cardiothoracic surgery. Their blood sample…

The role of patient specific morphology and contractility of the left atrial appendage on the thromboembolic risk in atrial fibrillation

2022

The vast majority of thrombi that cause ischemic complications in atrial fibrillation originate in the left atrial appendage. The left atrial appendage is an anatomical structure that starts from the left atrium, characterized by a wide morphological variability between individuals. This work analyses simulated hemodynamic for different patient-specific models of the left atrial appendage, using computational fluid-structure interaction studies, modelling the effect of changes in contractility and shape resulting from atrial fibrillation. Three operating conditions were analysed: sinus rhythm, acute atrial fibrillation, and chronic atrial fibrillation. These were simulated on four patient-s…