Search results for "Filament"

Detection of cosmic filaments using the Candy model

2004

We propose to apply a marked point process to automatically delineate filaments of the large-scale structure in redshift catalogues. We illustrate the feasibility of the idea on an example of simulated catalogues, describe the procedure, and characterize the results. We find the distribution of the length of the filaments, and suggest how to use this approach to obtain other statistical characteristics of filamentary networks.

Effetti trasversi nella propagazione di fasci ottici in vetri ad alto indice

2008

We investigate beam propagation in a novel Heavy Metal Oxide glass, reporting near infrared beam self-confinement and solitons, filamentation, interactions and conical emission at picoseconds and discussing them with the aid of a model.

Identificazione e localizzazione di citocheratine nelle Ascidie.

2004

Demo 162. Ilustración de la fuerza de Lorentz con una bombilla de filamento de carbono

2021

Se presenta una demostración de aula que muestra que el filamento de carbono de la bombilla vibra cuando circula corriente AC y se le aproxima un imán. Esto demuestra que un elemento de corriente eléctrica es una fuente del campo magnético y sirve de ilustración de la fuerza de Lorentz. A classroom demonstration is presented showing that the carbon filament in the light bulb vibrates when AC current flows and is approached by a magnet. This phenomenon shows that an element of electric current is a source of the magnetic field and illustrates the Lorentz force.

Gelation of semiflexible polyelectrolytes by multivalent counterions

2012

Filamentous polyelectrolytes in aqueous solution aggregate into bundles by interactions with multivalent counterions. These effects are well documented by experiment and theory. Theories also predict a gel phase in isotropic rodlike polyelectrolyte solutions caused by multivalent counterion concentrations much lower than those required for filament bundling. We report here the gelation of Pf1 virus, a model semiflexible polyelectrolyte, by the counterions Mg(2+), Mn(2+) and spermine(4+). Gelation can occur at 0.04% Pf1 volume fraction, which is far below the isotropic-nematic transition of 0.7% for Pf1 in monovalent salt. Unlike strongly crosslinked gels of semiflexible polymers, which stif…

The identification and localization of two intermediate filament proteins in the tunic of Styela plicata (Tunicata, Styelidae).

2009

The intermediate filament (IF) proteins Styela C and Styela D from the tunicate Styela (Urochordata) are co-expressed in all epidermal cells and they are thought to behave as type I and type II keratins. These two IF proteins, Styela C and Styela D, were identified in immunoblots of proteins isolated from the tunic of Styela plicata. The occurrence and distribution of these proteins within the tunic of this ascidian was examined by means of immunofluorescence and immunoperoxidase techniques, using anti-Styela C and anti-Styela D antibodies. In addition, immuno-electron microscopy of the tunic showed that the two proteins are located in the cuticle layer and in the tunic matrix. These result…

Differential VASP phosphorylation controls remodeling of the actin cytoskeleton

2009

Proteins of the Enabled/vasodilator-stimulated phosphoprotein (Ena/VASP) family link signal transduction pathways to actin cytoskeleton dynamics. VASP is substrate of cAMP-dependent, cGMP-dependent and AMP-activated protein kinases that primarily phosphorylate the sites S157, S239 and T278, respectively. Here, we systematically analyzed functions of VASP phosphorylation patterns for actin assembly and subcellular targeting in vivo and compared the phosphorylation effects of Ena/VASP family members. Methods used were the reconstitution of VASP-null cells with `locked' phosphomimetic VASP mutants, actin polymerization of VASP mutants in vitro and in living cells, site-specific kinase-mediated…

Stabilization of Perivascular Mast Cells by Endothelial CNP (C-Type Natriuretic Peptide)

2020

Objective: Activated perivascular mast cells (MCs) participate in different cardiovascular diseases. Many factors provoking MC degranulation have been described, while physiological counterregulators are barely known. Endothelial CNP (C-type natriuretic peptide) participates in the maintenance of vascular barrier integrity, but the target cells and mechanisms are unclear. Here, we studied whether MCs are regulated by CNP. Approach and Results: In cultured human and murine MCs, CNP activated its specific GC (guanylyl cyclase)-B receptor and cyclic GMP signaling. This enhanced cyclic GMP–dependent phosphorylation of the cytoskeleton-associated VASP (vasodilator-stimulated phosphoprotein) and…

M-cadherin and its sisters in development of striated muscle

1999

Cadherins are calcium-dependent, transmembrane intercellular adhesion proteins with morphoregulatory functions in the development and maintenance of tissues. In the development of striated muscle, the expression and function of mainly M-, N-, and R-cadherin has been studied so far. While these three cadherins are expressed in skeletal muscle cells, of these only N-cadherin is expressed in cardiac muscle. In this review, M-, N-, and R-cadherin are discussed as important players in the terminal differentiation and possibly also in the commitment of skeletal muscle cells. Furthermore, reports are described which evaluate the essential role of N-cadherin in the formation of heart tissue.

Association of serum neurofilament light chain levels and neuropsychiatric manifestations in systemic lupus erythematosus

2021

Background: The aim was to evaluate the diagnostic potential of serum neurofilament light chain (sNfL) measurements in patients with neuropsychiatric systemic lupus erythematosus (NPSLE). Methods: sNfL levels were determined by single molecule array assay in a retrospective cross-sectional cohort of 144 patients with systemic lupus erythematosus (SLE). After log-transformation of sNfL levels, mean sNfL levels were compared between NPSLE patients and SLE patients without neuropsychiatric disease using Student’s t test. Furthermore, the association of different neuropsychiatric manifestations with sNfL levels was assessed using a one-way analysis of variance (ANOVA) with post hoc analysis. As…