Search results for "Fires"
showing 9 items of 129 documents
Topical anti-inflammatory potential of quercetin in lipid-based nanosystems: In vivo and in vitro evaluation
2013
Purpose: To develop quercetin-loaded phospholipid vesicles, namely liposomes and PEVs (Penetration Enhancer-containing Vesicles), and to investigate their efficacy on TPA-induced skin inflammation. Methods: Vesicles were made from a mixture of phospholipids, quercetin and polyethylene glycol 400 (PEG), specifically added to increase drug solubility and penetration through the skin. Vesicle morphology and self-assembly were probed by Cryo-Transmission Electron Microscopy and Small/Wide Angle X-ray Scattering, as well as the main physico-chemical features by Light Scattering. The anti-inflammatory efficacy of quercetin nanovesicles was assessed in vivo on TPA-treated mice dorsal skin by the d…
Calcium Pre-Rinse: Effect on permeability of dentin tubules by fluoride rinse
2019
Background The aim of this study was to evaluate whether calcium (CaL) solution would enhance the capacity of sodium fluoride (NaF) solution in reducing the permeability of hypersensitive dentin. Material and Methods Thirty-two Wistar rats ingested for 45 days acidic isotonic drink (Gatorade, pH 2.7) ad libitum to induce dental erosion. Then, molar teeth received a cold stimulus to confirm the presence and score the intensity of dentin hypersensitivity based on body contraction and noise. Animals were allocated to four groups (n=8), according to the solution(s) applied in the oral cavity: NaF (12 mmol/L, 1 min); CaL (150 mmol/L, 1 min); CaL followed by NaF (CaF+NaF, 1 min each); distilled w…
Compound climate extreme events threaten migratory birds’ conservation in western U.S.
2022
In a warming world, more intense and frequent compound climate extreme events pose serious challenges to biodiversity and conservation on Earth as one of the 2030 United Nations’ sustainable development goals (SDGs): “Life On Land” (SDG 15). In summer 2020, concurrent swelling wildfires and a sudden cold snap in the western U.S. killed a massive number of migratory birds. In August 2020, the hot and humid weather in response to the wildfire radiation and the oceanic evaporation could result in killing heat stress for migratory birds along the coastal shoreline, particularly in California. The heat and smoke of wildfires forced the migratory birds to abandon such feeding grounds towards inla…
Microneedling dilates the follicular infundibulum and increases transfollicular absorption of liposomal sepia melanin
2015
Gabriel Serrano,1 Patricia Almudéver,2 Juan M Serrano,3 Julio Cortijo,2 Carmen Faus,1 Magda Reyes,1 Inmaculada Expósito,3 Ana Torrens,3 Fernando Millán1 1Clínica Dermatológica Serrano, 2Department of Pharmacology, University of Valencia, 3Research and Development Department, Sesderma Laboratories, Valencia, Spain Abstract: Encapsulation of chemicals in liposomes and microneedling are currently used techniques to enhance the penetration of several substances through skin and hair. In this study, we apply a liposomal melanin–fluorescein compound to an ex vivo model of human skin, using a new electrical microneedling device (Nano…
Fire in operating room: The adverse "never" event. Case report, mini-review and medico-legal considerations.
2020
Abstract The patient’s security and safety represent a topic of great importance for public health that led several healthcare organizations in many Countries to share documents to promote risk management and preventing adverse events. Surgical Fire (SF) is an infrequent adverse event generally occurring in the operating room (OR) and consisting of a fire that occurs in, on, or around a patient undergoing a medical or surgical procedure. Here a medico-legal case involving a 65-year-old woman reporting burns to the neck due to an SF during a thyroidectomy was described. A literature review was performed using Pubmed and Scopus databases, focusing on epidemiology, causes, prevention activitie…
Study of Intumescent Coatings Growth for Fire Retardant Systems in Naval Applications: Experimental Test and Mathematical Model
2022
Onboard ships, fire is one of the most dangerous events that can occur. For both military and commercial ships, fire risks are the most worrying; for this reason they have an important impact on the design of the vessel. The intumescent coatings react when heated or in contact with a living flame, and a multi-layered insulating structure grows up, protecting the underlying structure. In this concern, the aim of the paper is to evaluate the intumescent capacity of different composite coatings coupling synergistically modeling and experimental tests. In particular, the experiments have been carried out on a new paint formulation, developed by Colorificio Atria S.r.l., in which the active comp…
Inulin-Based Polymeric Micelles Functionalized with Ocular Permeation Enhancers: Improvement of Dexamethasone Permeation/Penetration through Bovine C…
2021
Ophthalmic drug delivery is still a challenge due to the protective barriers of the eye. A common strategy to promote drug absorption is the use of ocular permeation enhancers, while an innovative approach is the use of polymeric micelles. In the present work, the two mentioned approaches were coupled by conjugating ocular permeation enhancers (PEG2000, carnitine, creatine, taurine) to an inulin-based co-polymer (INU-EDA-RA) in order to obtain self-assembling biopolymers with permeation enhancer properties for the hydrophobic drug dexamethasone (DEX). Inulin derivatives were properly synthetized, were found to expose about 2% mol/mol of enhancer molecules in the side chain, and resulted abl…
AGGIORNAMENTO SULLA DISTRIBUZIONE DEL SUCCIACAPRE Caprimulgidae) IN SICILIA CAPRIMULGUS EUROPAEUS (Aves
2021
Caprimulgus europaeus In recent years Update on the distribution of breeding Nightjar in Sicily. there have been numerous observations of Nightjar in areas where it had never previously been observed. In some cases the reason may be a deeper exploration, but in other cases the possible explanation is the expansion of the species. However, it is quite interesting the change in the habitat by this species. The present paper provides an update of its status based on data collected in the fifteen years following the publication of the last Sicilian Atlas of breeding birds.
Análisis conjunto y espacios naturales: una aplicación al Paraje Natural del Desert de les Palmes
2007
We use stated preference methods to analyze consumer preferences on the attributes of protected natural areas and to estimate the willingness to pay for reducing the risk of fires in the site. For the first goal, conjoint analysis is used. Three attributes are considered: biodiversity, dimension of the natural area and the economic contribution that would have to be made for its maintenance and preservation. The willingness to pay for reducing the risk of fires has been estimated using choice experiment. The data have been gathered from a mail survey conducted among people living near the Desert de les Palmes Park, a protected area located in the Valencian Community (Spain). En el trabajo s…