Search results for "Fluid Dynamic"
showing 10 items of 1034 documents
Novel dual-flow perfusion bioreactor for in vitro pre-screening of nanoparticles delivery: design, characterization and testing
2021
An advanced dual-flow perfusion bioreactor with a simple and compact design was developed and evaluated as a potential apparatus to reduce the gap between animal testing and drug administration to human subjects in clinical trials. All the experimental tests were carried out using an ad hoc Poly Lactic Acid (PLLA) scaffold synthesized via Thermally Induced Phase Separation (TIPS). The bioreactor shows a tunable radial flow throughout the microporous matrix of the scaffold. The radial perfusion was quantified both with permeability tests and with a mathematical model, applying a combination of Darcy's Theory, Bernoulli's Equation, and Poiseuille's Law. Finally, a diffusion test allowed to in…
2016
Abstract. Various geoscientific applications require a fast prediction of fracture permeability for an optimal workflow. Hence, the objective of the current study is to introduce and validate a practical method to characterize and approximate single flow in fractures under different stress conditions by using a core-flooding apparatus, in situ X-ray computed tomography (CT) scans and a finite-volume method solving the Navier–Stokes–Brinkman equations. The permeability of the fractured sandstone sample was measured stepwise during a loading–unloading cycle (0.7 to 22.1 MPa and back) to validate the numerical results. Simultaneously, the pressurized core sample was imaged with a medical X-ray…
Non-equilibrium thermodynamics, heat transport and thermal waves in laminar and turbulent superfluid helium
2018
This review paper puts together some results concerning non equilibrium thermodynamics and heat transport properties of superfluid He II. A one-fluid extended model of superfluid helium, which considers heat flux as an additional independent variable, is presented, its microscopic bases are analyzed, and compared with the well known two-fluid model. In laminar situations, the fundamental fields are density, velocity, absolute temperature, and heat flux. Such a theory is able to describe the thermomechanical phenomena, the propagation of two sounds in liquid helium, and of fourth sound in superleak. It also leads in a natural way to a two-fluid model on purely macroscopical grounds and allow…
Solid sediment transport in turbulent channel flow over irregular rough boundaries
2017
Abstract The presence of a loading of dispersed particles in a turbulent flow affects the dynamics of the carrier flow field which, in turn, drives grains movement. The focus of the paper is on the analysis of the coupling effects between near-bed turbulence structures and the dynamics of dispersed suspended solid particles in wall-bounded turbulent multiphase flows. We consider turbulent horizontal channel flows bounded by rough boundaries. The friction Reynolds number of the unladen flow is R e τ = 180 and the dispersed phase spans one order of magnitude of particle diameter. To analyze sedimentation and suspended phase transport, we adopt concepts and modeling ideas derived from the Eule…
Inferring rheology and geometry of subsurface structures by adjoint-based inversion of principal stress directions
2020
SUMMARY Imaging subsurface structures, such as salt domes, magma reservoirs or subducting plates, is a major challenge in geophysics. Seismic imaging methods are, so far, the most precise methods to open a window into the Earth. However, the methods may not yield the exact depth or size of the imaged feature and may become distorted by phenomena such as seismic anisotropy, fluid flow, or compositional variations. A useful complementary method is therefore to simulate the mechanical behaviour of rocks on large timescales, and compare model predictions with observations. Recent studies have used the (non-linear) Stokes equations and geometries from seismic studies in combination with an adjoi…
Accumulation and self-organization in hydrofracturetransport of fluids
2003
Abstract Propagation of “mobile hydrofractures” is one of several mechanisms to transport fluids. Analogue experiments show howthis transport mechanism is intimately linked with accumulation, by stepwise mergers of fluid batches. Analogue experiments and numerical modelling indicate that such stepwise transport and accumulation may lead to the establishment of a self-organised critical state.
CFD simulation of gas-liquid hydrodynamics in a rectangular air–lift loop reactor
2006
Computational Fluid Dynamics is an increasingly important tool for carrying out realistic simulations of process apparatuses. As a difference from single phase systems, for multi phase systems the development of CFD models is still at its early stages. Moreover, gas-liquid systems are characterised by an additional complexity level, related to the fact that, as a difference with solid-liquid systems, bubble sizes are not known in advance, being rather the result of formation and breakage-coalescence dynamics, and therefore of complex phenomena related to flow dynamics and interfacial effects. In the present work CFD simulations of gas-liquid air-lift reactors are reported. All bubbles are a…
Turbulent heat transfer in spacer-filled channels: Experimental and computational study and selection of turbulence models
2019
Abstract Heat transfer in spacer-filled channels of the kind used in Membrane Distillation was studied in the Reynolds number range 100–2000, encompassing both steady laminar and early-turbulent flow conditions. Experimental data, including distributions of the local heat transfer coefficient h, were obtained by Liquid Crystal Thermography and Digital Image Processing. Alternative turbulence models, both of first order (k-e, RNG k-e, k-ω, BSL k-ω, SST k-ω) and of second order (LRR RS, SSG RS, ω RS, BSL RS), were tested for their ability to predict measured distributions and mean values of h. The best agreement with the experimental results was provided by first-order ω-based models able to …