Search results for "Footprint"
showing 10 items of 121 documents
Carbon Footprint Analysis: Towards a Projects Evaluation Model for Promoting Sustainable Development
2013
Abstract Climate change and global warming are internationally recognized as current issues, driving negative effects on humanity, and being mainly caused by GHG emissions generated both from industrial activities, and from other anthropogenic activities. Restoring the ecological balance requires urgent action to reduce GHG emissions. In this respect, the European Union has set the target to reduce the GHG emissions by 20% until 2020, compared to 1990 level. This paper presents a methodology to develop a model for carbon footprint calculation, for assessing and reducing GHG emissions generated by European funds financed projects.
Transcriptional regulation of the stem cell leukemia gene by PU.1 and Elf-1.
1998
Abstract The SCL gene, also known astal-1, encodes a basic helix-loop-helix transcription factor that is pivotal for the normal development of all hematopoietic lineages. SCL is expressed in committed erythroid, mast, and megakaryocytic cells as well as in hematopoietic stem cells. Nothing is known about the regulation of SCL transcription in mast cells, and in other lineages GATA-1 is the only tissue-specific transcription factor recognized to regulate the SCL gene. We have therefore analyzed the molecular mechanisms underlyingSCL expression in mast cells. In this paper, we demonstrate that SCL promoter 1a was regulated by GATA-1 together with Sp1 and Sp3 in a manner similar to the situati…
Regulation of the sea urchin early H2A histone gene expression depends on the modulator element and on sequences located near the 3' end
1999
Abstract Transcription of the sea urchin early histone genes occurs transiently during early cleavage, reaching the maximum at the morula stage and declining to an undetectable level at the gastrula stage. To identify the regulatory elements responsible for the timing and the levels of transcription of the H2A gene, we used promoter binding studies in nuclear extracts and microinjection of a CAT transgene driven by the early H2A promoter. We found that morula and gastrula nuclear proteins produced indistinguishable DNase I footprint patterns on the H2A promoter. Two sites of interactions, centred on the modulator/enhancer and on the CCAAT box respectively, were detected. Deletion of the mod…
Physiological activation of the IgH 3' enhancer in B lineage cells is not blocked by Pax-5.
1996
The mouse 3' enhancer contains a high-affinity binding site for the paired box protein Pax-5. Here, we demonstrate by genomic footprinting that the rat 3' enhancer contains a low-affinity binding site for Pax-5, which is occupied in activated splenic B cells. Thus, binding of Pax-5 to the IgH 3' enhancer appears to be evolutionarily conserved in rodents. Analysis of Pax-5 expression in primary B cells demonstrates that Pax-5 remains expressed after 4 days of lipopolysaccharide (LPS) induction, but is down-regulated in 5-day stimulated cells. Similarly, the expression of Pax-5 is down-regulated in vivo in activated large splenocytes, in contrast to small resting cells. Multimerization of the…
Learning Automaton Based On-Line Discovery and Tracking of Spatio-temporal Event Patterns
2010
Published version of an article from the book: Lecture Notes in Computer Science, 2010, Volume 6230/2010, 327-338. The original publication is available at Springerlink. http://dx.doi.org/10.1007/978-3-642-15246-7_31 Discovering and tracking of spatio-temporal patterns in noisy sequences of events is a difficult task that has become increasingly pertinent due to recent advances in ubiquitous computing, such as community-based social networking applications. The core activities for applications of this class include the sharing and notification of events, and the importance and usefulness of these functionalites increases as event-sharing expands into larger areas of one’s life. Ironically, …
Secondary structure determination of conserved SARS-CoV-2 RNA elements by NMR spectroscopy
2020
AbstractThe current pandemic situation caused by the Betacoronavirus SARS-CoV-2 (SCoV2) highlights the need for coordinated research to combat COVID-19. A particularly important aspect is the development of medication. In addition to viral proteins, structured RNA elements represent a potent alternative as drug targets. The search for drugs that target RNA requires their high-resolution structural characterization. Using nuclear magnetic resonance (NMR) spectroscopy, a worldwide consortium of NMR researchers aims to characterize potential RNA drug targets of SCoV2. Here, we report the characterization of 15 conserved RNA elements located at the 5′ end, the ribosomal frameshift segment and t…
A new tool for evaluating and/or selecting analytical methods: Summarizing the information in a hexagon
2019
Abstract A quantitative evaluation tool is proposed, which aims to assess optimal selection or/and testing of analytical methods. Objective criteria related to analytical performance, sustainability, environmental impact and economic cost are evaluated through the definition of penalty points divided into five different blocks, namely, figures of merit, toxicity and safety, residues, carbon footprint and economic cost. For each block, the overall qualification is scaled from 0 to 4 and it is depicted on a regular hexagonal pictogram that allows a user friendly comparison of analytical procedures. The present evaluation tool aims to be a guideline for evaluating and/or selecting analytical p…
An Algorithm for Optimal Sizing of BESS in Smart Islands Energy Communities: the Case of Pantelleria
2021
Energy Communities (EC) are a promising solution to reduce both the carbon footprint and the impact of Renewable Energy Sources (RES) on the distribution grid. Based on a simple energy sharing principle, EC can be decisive in the next future energy transition of some problematic territories, like small islands not supplied by the main power grid. By integrating Battery Energy Storage Systems (BESS), it is possible to improve the EC performance. However, due to the still high BESSs unit prices, the goal of this work is to find the optimal size of BESSs, under various conditions, which combines the need to maximize shared energy and the possible revenue of EC actors. To set this multi-objecti…
The playa environments of the Lodève Permian basin (Languedoc-France).
2008
28 pages; International audience; The Lodève Permian synrift sequence is represented by thick stacked climate-controled playa cycles which have been constrained by structural, sedimentological, geochemical and paleontological processes. The present paper merges the different results in order to better constrain the dynamics and palaeoecologycal evolution of the playa system from Late Cisuralian to Early Lopingian time. In this depositional environment, thining upwards sheet-flood sequences represent flooding events; they are relayed by ephemeral ponding, suspension settling and limited carbonate precipitation accompanied by large amounts of shallow to subaerial sedimentary structures (curre…
Anza palaeoichnological site, Late Cretaceous, Morocco. Part III: Comparison between traditional and photogrammetric records
2020
11 pages; International audience; The present study evaluates a methodological workflow that could identify dinosaur tracks and trackways more comprehensively at outcrop scale. The approach described here is based both on 3D modelling by photogrammetry at different resolutions, and on suitably processed digital elevation models (DEMs). The ichnosite of Anza, Morocco, was chosen to demonstrate the efficiency of the proposed pipeline, because 323 dinosaur and pterosaur tracks discovered there have already been published. One subsector containing 89 tracks, identified in the two companion works that followed a traditional approach, was selected and divided into four subzones. By combining diff…