Search results for "Forced"

Failure Load and Collapse Mode of an RC Beam in a Large Collapsed Roof

2021

The present work focused on the determination of the collapse load and of the failure mode of a collapsed framed structure constructed in the South of Italy and failed in 2004 under its self-weight. Information available was the results on extensive experimental test campaign, for the determination of mechanical properties of concrete and steel bars of beams, floors and columns involved in the failure. Moreover, draws of original design with construction details and design rules valid in Italy at the time of construction were found. A simple monodimensional beam model for prediction of load-deflection curve, able to include degradation of constituent materials (concrete, steel and bond) was…

Fluticasone propionate/formoterol: a fixed-combination therapy with flexible dosage.

2014

International guidelines describe asthma control as the main outcome of asthma management. Prevention of symptoms, improved quality of life, and reduction of exacerbations are the main components, consequently decreasing health care costs. However, many of these objectives remain unmet in real life: several surveys show that a large proportion of asthmatic patients are not well controlled despite the efficacy of current available treatment. Several randomized controlled clinical trials indicate that combining inhaled corticosteroids and long-acting β2-agonists, by means of a single inhaler, greatly improves the management of the disease. The results of 9 multicenter phase III clinical studi…

Impact of domestic mould exposure on Aspergillus biomarkers and lung function in patients with chronic obstructive pulmonary disease

2021

International audience; Patients with chronic obstructive pulmonary disease (COPD) are frequently colonised or sensitised by Aspergillus, but clinical significance remains unclear. Furthermore, little is known on the impact of indoor mould exposure during COPD. In this study, we assessed the relationship between domestic mould exposure, Aspergillus biomarkers and COPD severity during acute exacerbation and at stable state. Aspergillus section Fumigati culture in sputum and anti-Aspergillus antibodies detection (IgG and precipitins) were followed up in COPD patients that were prospectively recruited during exacerbation (n = 62), and underwent a visit at stable state after 18 months (n = 33).…

Bond strength of cemented fiber posts to teeth with simulated internal root resorption

2020

Made available in DSpace on 2021-06-25T10:58:34Z (GMT). No. of bitstreams: 0 Previous issue date: 2020-03-01 Background: Teeth with internal root resorption (IRR) have guarded prognosis, considering that IRR defect could influence on the post bond strength. The aim of this study was to evaluate the bond strength and the bond interface between different glass fiber-reinforced posts (FRP) after cementation in teeth with simulated internal root resorption (IRR). Material and Methods: Forty-five (45) human premolar roots with simulated IRR were embedded in acrylic resin blocks and cross-sectioned into two segments, enabling them to be re-approximated by screws. Intracanal medication was inserte…

Long-term, open-labeled extension study of idursulfase in the treatment of Hunter syndrome.

2011

Purpose: This study evaluated the safety and effectiveness of long-term enzyme replacement therapy with idursulfase (recombinant human iduronate-2-sulfatase) in patients with Hunter syndrome. Methods: All 94 patients who completed a 53-week double-blinded study of idursulfase enrolled in this open-labeled extension study and received intravenous idursulfase at a dose of 0.5 mg/kg weekly for 2 years, and clinical outcomes and safety were assessed. Results: No change in percent predicted forced vital capacity was seen, but absolute forced vital capacity demonstrated sustained improvement and was increased 25.1% at the end of the study. Statistically significant increases in 6-minute walking t…

Inspiration through the nose increases the bronchoprotective effect of lung inflation

2007

On the Fundamental Period of Infilled RC Buildings

2015

This paper investigates the fundamental period of vibration of RC buildings by means of finite element macro-modelling and modal eigenvalue analysis. As a base study, a number of 14-storey RC buildings have been considered \"according to code designed\" and \"according to code non-designed\". Several parameters have been studied including the number of spans; the span length in the direction of motion; the stiffness of the infills; the percentage openings of the infills and; the location of the soft storeys. The computed values of the fundamental period are compared against those obtained from seismic code and equations proposed by various researchers in the literature. From the analysis of…

Analysis and optimization of hybrid double lap aluminum-GFRP joints

2014

In this paper a systematic investigation of the mechanical performance of hybrid double-lap Al-GFRP bonded-bolted joints, has been carried out by using experimental analyses and numerical simulations. In order to detect the optimal geometric configuration, as well as to highlight the contribution of adhesive and bolts, the results relative to hybrid joints have been compared with those of simply adhesively bonded and simply bolted joints. The experimental and numerical results have shown that by using the minimum overlap length provided from theory, the bolt leads to a significant decreasing of both the maximum shear and the maximum peel stresses in the adhesive layer and, consequently, the…

Numerical experimental analysis of hybrid double lap aluminum-CFRP joints

2015

Abstract Due to their reliability and ease of assembly, both the adhesively bonded and the mechanical joints are commonly used in different fields of modern industrial design and manufacturing, to joint composite materials or composites with metals. As it is well known, adhesively bonded joints are characterized by high stiffness and good fatigue life, although delamination phenomena localized near the free edges may limit their use, especially for applications where corrosive environments and/or moisture can lead to premature failure of the bonding. In these cases, a possible alternative is given by the well-known mechanical joints. On the contrary, these last joints (bolted, riveted) requ…

Stationary sets and asymptotic behavior of the mean curvature flow with forcing in the plane

2020

We consider the flat flow solutions of the mean curvature equation with a forcing term in the plane. We prove that for every constant forcing term the stationary sets are given by a finite union of disks with equal radii and disjoint closures. On the other hand for every bounded forcing term tangent disks are never stationary. Finally in the case of an asymptotically constant forcing term we show that the only possible long time limit sets are given by disjoint unions of disks with equal radii and possibly tangent. peerReviewed