Search results for "Form."
showing 10 items of 43419 documents
Extracellular Vesicles as Shuttles of Tumor Biomarkers and Anti-Tumor Drugs
2014
Extracellular vesicles (EV) include vesicles released by either normal or tumor cells. EV may exceed the nanometric scale (microvesicles), or to be within the nanoscale, also called exosomes. Thus, it appears that only exosomes and larger vesicles may have the size for potential applications in nanomedicine, in either disease diagnosis or therapy. This is of particular interest for research in cancer, also because the vast majority of existing data on EV are coming from pre-clinical and clinical oncology. We know that the microenvironmental features of cancer may favor cell-to-cell paracrine communication through EV, but EV have been purified, characterized, and quantified from plasma of tu…
Comparative histological and immunohistochemical study of ameloblastomas and ameloblastic carcinomas
2017
Background This study aimed to compare the histological and immunohistochemical characteristics of ameloblastomas (AM) and ameloblastic carcinomas (AC). Material and Methods Fifteen cases of AM and 9 AC were submitted to hematoxilin and eosin (H&E) and immunohistochemical analysis with the following antibodies: cytokeratins 5,7,8,14 and 19, Ki-67, p53, p63 and the cellular adhesion molecules CD138 (Syndecan-1), E-cadherin and β-catenin. The mean score of the expression of Ki-67 and p53 labelling index (LIs) were compared between the groups using the t test. A value of p<0.05 was considered to be statistically significant. Results All cases were positive for CKs 5, 14 and 19, but negative fo…
Tunnetyön kuormittavuus terveydenhuoltoalalla : palvelumotivaatio ja transformationaalinen johtajuus puskuroivina voimavaroina
2015
Tämän pro gradu -tutkielman tavoitteena oli kartoittaa tunnetyön kuormittavuutta suomalaisella terveydenhuoltoalalla. Työn vaatimusten ja voimavarojen mallia (JD-R) hyödyntäen tutkimme, kuinka tunnetyön kuormittavuus työn vaatimustekijänä ja transformationaalinen johtajuus sekä palvelumotivaatio työn voimavaratekijöinä ovat yhteydessä työuupumukseen. Tutkimusaineistoon valikoitui 1450 hoitotyöntekijää, joiden tunnetyön kuormittavuutta (mitattuna emotionaalisella dissonanssilla), palvelumotivaatioita, koettua transformationaalista johtajuutta ja työuupumusta (mitattuna uupumusasteisena väsymyksenä) kartoitettiin kyselylomakkeen avulla. Tutkimushypoteeseina oli, että tunnetyön kuormittavuus o…
Roles of Exogenous Technologies in Vehicle Innovation: Cases from a Japan’s Automotive Parts Manufacturing Firm
2017
This paper explores the roles of technological innovations in the growth of Japan’s motor vehicle industry, mainly from technology spillover perspective from the early 2000s to today. An empirical analysis focusing on business performances, R&D investments, and patent applications taking a noteworthy unique case in Japan was attempted. Empirical analyses on the productivity of patent to technology stock, use of exogenous technologies for their own technological innovation on its Automotive Business Unit elucidated that innovation capabilities, incorporation of exogenous technologies, and profit generation makes a virtuous cycle of continuous technological innovation. Furthermore, we fou…
Tuottavuusparadoksi liiketoimintaa haittaavana ilmiönä
2009
Pyykkö, Antti Tietojärjestelmätieteen kandidaatintutkielma / Antti Pyykkö Jyväskylä: Jyväskylän yliopisto, 2009, 43 s. Kandidaatintutkielma Tässä tutkielmassa tutkitaan kirjallisuuskatsauksen muodossa tuottavuusparadoksia ja syitä, joista tuottavuusparadoksi johtuu. Tutkielmassa avataan kattavasti tuottavuuden ja tuottavuusparadoksin käsitteet sekä esitellään tuottavuusparadoksin historia. Tuottavuusparadoksi tarkoittaa tilannetta, jossa yrityksen informaatioteknologiaan tekemät suuret investoinnit eivät johda merkittävään tuottavuuden kasvuun, tai se ei kasva ollenkaan. Tässä tutkielmassa käsitteellä informaatioteknologia tarkoitetaan kaikkia tietoteknisiä resursseja aina laitteistoista t…
Nelle forme degli insediamenti
2013
Il testo descrive struttura e forme dell’insediamento storicamente conformato nel territorio della Punta Occidentale della Sicilia nonché le recenti modificazioni e le tendenze in atto come risultanti di risposte date localmente ad una crescente domanda reale o potenziale di presenze turistiche. Lo studio dei caratteri e dell’evoluzione morfologica degli insediamenti consente di approdare ad una prima classificazione di quelle forme della stanzialità (residenziale, del lavoro, turistica e dei servizi) che sembrano favorire il radicamento di attività turistiche compatibili con la qualità delle risorse, più di altre che, invece, sembrano ostacolarlo.
Il ruolo della formazione per il turismo
2013
Enhancing the European Cyber Threat Prevention Mechanism
2021
This research will determine how it is possible to implement the national cyber threat prevention system into the EU level Early Warning System. Decision makers have recognized that the lack of cooperation between EU member countries affects public safety at the international level. Separate operational functions and procedures between national cyber situation centers create challenges. One main problem is that the European Union does not have a common cyber ecosystem concerning intrusion detection systems for cyber threats. Also, privacy and citizens’ security as topics are set against each other. The research will comprise a new database for the ECHO Early Warning System concept.
Intervention Effect Rates as a Path to Research Relevance : Information Systems Security Example
2018
In the current information systems security (ISS) research, new theory contributions are especially valued. This research typically reflects the following formula: Suggest a new theory (or set of constructs) of ISS and show that it is empirically supported, then suggest another new theory (or set of constructs with some linkages) and show that it is empirically supported, and so on. Despite the merits of this approach, it leaves out many important scientific aspects. For example, after more than 30 years of ISS research, (1) we know little about the conditions and situations to which new theories (or constructs) do not apply; (2) we do not know which new theories are more effective than oth…
Co-Evolutionary Coupling Between Captured and Uncaptured GDP Cycles : Cross Learning from Amazon and Finland Models for Sustainability
2019
A solution to the critical problem of a dilemma between R&D expansion and productivity decline that a majority of information and communication technology (ICT) leaders have been confronting in the digital economy is expected. It can be expected by a spinoff from economic functionality-seeking GDP-based coevolution cycle to supra-functionality beyond an economic value-seeking uncaptured GDP-driven coevolution cycle. However, the transformation dynamism remains a black box. By means of numerical simulations based on empirical analyses of the development trajectories of global ICT leaders, focusing on Amazon and Finland, together with an intensive review of preceding analyses, this paper atte…