Search results for "Form."

Bioetyka konfucjańska. Zagadnienie świadomej zgody w kontekście tradycyjnego chińskiego światopoglądu

2017

Tekst dotyczy bioetyki w Chinach, w szczególności bioetyki konfucjańskiej, i ukazuje funkcjonowanie medycyny oraz problemów bioetycznych w szerszym kontekście kulturowym. Tradycyjny chiński światopogląd i obyczajowość wpływają na konceptualizację i realizację poszczególnych kwestii bioetycznych. W tekście ukazany zostaje problem świadomej zgody i różnic kulturowych w jej pojmowaniu i egzekwowaniu. Ze względu na zupełnie odmienne postrzeganie relacji między jednostką a grupą w Chinach w porównaniu z kulturami indywidualistycznymi (Europa Zachodnia, Ameryka Północna, Australia) bioetycy chińscy przewartościowali pojęcie świadomej zgody, wprowadzając konkurencyjną koncepcję community-assisted …

Austrijas un Šveices mazās vēstniecības

2018

Šķīrējtiesas līguma tiesiskais regulējums Latvijas Republikā.

2017

Bakalaura darbā pētīts šķīrējtiesas līguma, kā šķīrējtiesas procesa institūts Latvijas Republikas tiesību sistēmā un virspusēji, salīdzināšanas nolūkā - starptautiskajās tiesībās. Šķīrējtiesas līguma jēdziens analizēts kā tiesisks darījums uz līguma pamata Civillikuma izpratnē, interpretējot to atbilstoši šķīrējtiesas līguma specifikai. Atsevišķa darba nodaļa veltīta šķīrējtiesas līguma formas analīzei, jo tas ir viens no būtiskākajiem ar tā noslēgšanu un spēkā esamību saistītajiem jautājumiem. Darbā pētītas arī citas ar šķīrējtiesas līgumu saistītas problēmas, t.sk., par šķīrējtiesas līguma radīto saistību pāreju uz citām personām dažādu tiesību veidu nodošanas gadījumos, kā arī nepiecieša…

Profiling Dopamine-Induced Oxidized Proteoforms of β-synuclein by Top-Down Mass Spectrometry

2021

The formation of multiple proteoforms by post-translational modifications (PTMs) enables a single protein to acquire distinct functional roles in its biological context. Oxidation of methionine residues (Met) is a common PTM, involved in physiological (e.g., signaling) and pathological (e.g., oxidative stress) states. This PTM typically maps at multiple protein sites, generating a heterogeneous population of proteoforms with specific biophysical and biochemical properties. The identification and quantitation of the variety of oxidized proteoforms originated under a given condition is required to assess the exact molecular nature of the species responsible for the process under investigation…

Conformational investigation of alpha,beta-dehydropeptides. IX. N-Acetyl-(E)-alpha,beta-methylamide: stereoelectronic properties from infrared and th…

1998

The Fourier transform infrared spectra of Ac-(E)-deltaAbu-NHMe were analyzed to determine the predominant solution conformation(s) of this (E)-alpha,beta-dehydropeptide-related compound and the electron density perturbation in its amide groups. The measurements were performed in dichloromethane and acetonitrile in the region of mode vs (N-H), amide I, amide II and vs (C(alpha)=Cbeta). The equilibrium geometrical parameters, calculated by a method based on the density functional theory with the B3LYP functional and the 6-31G* basis set, were used to support spectroscopic interpretation and gain some deeper insight into the molecule. The experimental and theoretical data were compared with th…

Desymmetrization of Prochiral Cyclobutanones via Nitrogen Insertion: A Concise Route to Chiral γ‐Lactams

2021

Abstract Asymmetric access to γ‐lactams is achieved via a cyclobutanone ring expansion using widely available (1S,2R)‐1‐amino‐2‐indanol for chiral induction. Mechanistic analysis of the key N,O‐ketal rearrangement reveals a Curtin–Hammett scenario, which enables a downstream stereoinduction (up to 88:12 dr) and is corroborated by spectroscopic, crystallographic, and computational studies. In combination with an easy deprotection protocol, this operationally simple sequence allows the synthesis of a range of optically pure γ‐lactams, including those bearing all‐carbon quaternary stereocenters. In addition, the formal synthesis of drug molecules baclofen, brivaracetam, and pregabalin further …

Uniform rectifiability and ε-approximability of harmonic functions in Lp

2020

Suppose that E⊂Rn+1 is a uniformly rectifiable set of codimension 1. We show that every harmonic function is ε-approximable in Lp(Ω) for every p∈(1,∞), where Ω:=Rn+1∖E. Together with results of many authors this shows that pointwise, L∞ and Lp type ε-approximability properties of harmonic functions are all equivalent and they characterize uniform rectifiability for codimension 1 Ahlfors–David regular sets. Our results and techniques are generalizations of recent works of T. Hytönen and A. Rosén and the first author, J. M. Martell and S. Mayboroda. peerReviewed

On the Amount of Nonconstructivity in Learning Recursive Functions

2011

Nonconstructive proofs are a powerful mechanism in mathematics. Furthermore, nonconstructive computations by various types of machines and automata have been considered by e.g., Karp and Lipton [17] and Freivalds [11]. They allow to regard more complicated algorithms from the viewpoint of much more primitive computational devices. The amount of nonconstructivity is a quantitative characterization of the distance between types of computational devices with respect to solving a specific problem. In the present paper, the amount of nonconstructivity in learning of recursive functions is studied. Different learning types are compared with respect to the amount of nonconstructivity needed to lea…

Алгебра и дискретная математика: прикладные вопросы информатики

1989

Сборник содержит результаты исследований в области информатики, прикладной алгебры и дискретной математики.

Результаты германской биржевой реформы 1896 года

1897

Izraksts no " № 44 Вѣстника Финансовъ, Промышленности и Торговли за 1897 г."