Search results for "Format"

ANALYSIS OF RESPIRATORY SINUS ARRHYTHMIA MECHANISMS IN INFORMATION DOMAIN

2018

Digital health interventions for children with ADHD

2020

Attention deficit hyperactivity disorder (ADHD) is a childhood-onset disorder characterised by a persistent pattern of symptoms of inappropriate and impaired inattention, hyperactivity, or impulsivity, with difficulties often continuing into adulthood.1 It is estimated to affect 37·1 million children and young people (aged ≤20 years) worldwide.2 Although multiple ADHD treatments are available and widely used (eg, evidence-based behaviour therapy, medications, or a combination of both),3,4 their effectiveness has been questioned because they might not fully address the needs of many children with ADHD. Barriers to evidence-based treatment for ADHD include misconceptions and stigma, time, and…

Occupational exposure to pesticides and congenital malformations: A review of mechanisms, methods, and results

1998

Pesticides are chemicals that are widely used all over the world. Human beings can be exposed through environmental contamination and/or occupational use of pesticides. Although there is substantial information on the acute toxicity of many of these chemicals, available knowledge on delayed effects is much more limited. This paper reviews epidemiological studies on occupational exposure to pesticides, mainly in agricultural workers, and risk of congenital malformations. The discussion includes postulated mechanisms for birth defects from paternal or maternal exposure, a detailed review of method of the studies carried out so far on the relationship between occupational exposure to pesticide…

The relevance for Public Health of the mid-term and interim analyses of seasonal influenza vaccination effectiveness

2019

Worldwide, influenza is commonly recognized as a respiratory virus that causes a high number of deaths every year, especially among elderly adults and people with chronic illnesses. In order to reduce morbidity and mortality, many countries have implemented, in the last decades, universal influenza vaccination programs with special attention on groups at increased risk of developing the disease, such as pregnant women, children aged 6–59 months, elderly adults and individuals with specific chronic medical conditions. In real-world conditions, observational (nonrandomized) studies on vaccine effectiveness (VE) could measure,the risk reduction of contracting a disease and are considered the g…

Synchronization index for quantifying nonlinear causal coupling between RR interval and systolic arterial pressure after myocardial infarction

2002

The analysis of nonlinear couplings among cardiovascular variability series can improve the knowledge of the cardioregulatory mechanism and help to understand how it can be affected by pathologies. In this study, the influences of acute myocardial infarction (AMI) on the causal relationships between the heart period and the arterial pressure were investigated by a nonlinear dynamic approach based on the corrected cross-conditional entropy. Whereas the global synchronization index did not differentiate the post-AMI patients from the young and old control groups, the causal indexes evidenced the impairment of the baroreflex control and showed an increase of the mechanical driving of the RR in…

Prise en charge des proliférations épithéliales du sein avec et sans atypies : hyperplasie canalaire atypique, métaplasie cylindrique avec atypie, né…

2015

In the last few years, diagnostics of high-risk breast lesions (atypical ductal hyperplasia [ADH], flat epithelial atypia [FEA], lobular neoplasia: atypical lobular hyperplasia [ALH], lobular carcinoma in situ [LCIS], radial scar [RS], usual ductal hyperplasia [UDH], adenosis, sclerosing adenosis [SA], papillary breast lesions, mucocele-like lesion [MLL]) have increased with the growing number of breast percutaneous biopsies. The management of these lesions is highly conditioned by the enlarged risk of breast cancer combined with either an increased probability of finding cancer after surgery, either a possible malignant transformation (in situ or invasive cancer), or an increased probabili…

Linfedema: Diagnóstico diferencial y pruebas complementarias

2010

Objetivo Realizar una revisión y actualización del diagnóstico diferencial del linfedema y de las pruebas complementarias necesarias y presentar un algoritmo simplificado del diagnóstico. Estrategia de búsqueda. Se buscaron los artículos originales en las principales bases de datos: National Guideline Clearinghouse, Guidelines Finder de la National Electronic Library for Health del NHS británico, Cochrane Central Register of Controlled Trials, Web of Knowledge y Medline (19962009), y las monografías más relevantes sobre linfedema. Selección de estudios.Se valoró la relevancia de los artículos mediante la lectura del título y resumen, y se analizó el texto completo de aquellos considerados r…

Sclerosing Angiomatoid Nodular Transformation: Laparoscopic Splenectomy as Therapeutic and Diagnostic Approach at the Same Time

2018

Introduction. Sclerosing angiomatoid nodular transformation (SANT) of the spleen is a rare benign vascular lesion with unknown etiopathogenesis and with definite features of imaging, histopathology, and immunohistochemistry. It was first described by Martel et al. in 2004, and to date, only 151 cases have been reported.Case Description. We report a case of SANT of the spleen detected in a 66-year-old Caucasian, without comorbidities, presented to our department with epigastric pain. We, also, presented a review of the literature.Conclusions. SANT is a benign incidentally vascular condition in the majority of cases. The wide age and gender distribution in our review is in accordance with tha…

Uncontrolled immune response in acute myocardial infarction

2008

Recently, the theory that hyperinflammation is the body's primary response to potent stimulus has been challenged. Indeed, a deregulation of the immune system could be the cause of multiple organ failure. So far, clinicians have focused on the last steps of the inflammatory cascade. However, little attention has been paid to lymphocytes, which play an important role as strategists of the inflammatory response. Experimental evidence suggests a crucial role of T lymphocytes in the pathophysiology of atherosclerosis and acute myocardial infarction (AMI). In summary, from the bottom of an imaginary inverted pyramid, a few regulatory T-cells control the upper parts represented by the wide spectr…

Arteriovenous fistula of the vertebral artery in a female infant with hypotonia and cephalocorporal disproportion

2010

Background:  Congenital arteriovenous fistulas are exceptional in childhood and imply a therapeutic challenge. Case report: A 9-month-old female infant was studied for cephalocorporal disproportion, hypotonia, progressive muscular atrophy and hyperreflexia. Computed tomography of the brain and electroencephalography were normal. Electromyographic patterns suggested proximal myopathic involvement. A continuous murmur with systolic reinforcement was audible in the neck. Angioresonance detected intracranial aneurysmal dilatations behind the bulbo-medullary junction and cerebral panangiography evidenced a direct vertebrovertebral fistula with extra- and intra-cranial varices and extreme medulla…