Search results for "Forms"
showing 10 items of 668 documents
Multipartite entanglement in three-mode Gaussian states of continuous variable systems: Quantification, sharing structure and decoherence
2005
We present a complete analysis of multipartite entanglement of three-mode Gaussian states of continuous variable systems. We derive standard forms which characterize the covariance matrix of pure and mixed three-mode Gaussian states up to local unitary operations, showing that the local entropies of pure Gaussian states are bound to fulfill a relationship which is stricter than the general Araki-Lieb inequality. Quantum correlations will be quantified by a proper convex roof extension of the squared logarithmic negativity (the contangle), satisfying a monogamy relation for multimode Gaussian states, whose proof will be reviewed and elucidated. The residual contangle, emerging from the monog…
Probing Quantum Frustrated Systems via Factorization of the Ground State
2009
The existence of definite orders in frustrated quantum systems is related rigorously to the occurrence of fully factorized ground states below a threshold value of the frustration. Ground-state separability thus provides a natural measure of frustration: strongly frustrated systems are those that cannot accommodate for classical-like solutions. The exact form of the factorized ground states and the critical frustration are determined for various classes of nonexactly solvable spin models with different spatial ranges of the interactions. For weak frustration, the existence of disentangling transitions determines the range of applicability of mean-field descriptions in biological and physica…
Seismic stratigraphy of the north-westernmost area of the Malta Plateau (Sicily Channel): The Middle Pleistocene-Holocene sedimentation in a tidally …
2022
In this study we present the results of a seismic-stratigraphic analysis of sub-bottom profiles in the north-westernmost area of the Malta Plateau in order to define the depositional mechanisms for the upper Quaternary sequences. During this interval the morphology of the Malta Plateau was characterized by a ramp and bathymetries not exceeding 200 m. Two major unconformities, related to MIS 6 and MIS 2 (the latter corresponding to the Last Glacial Maximum, LGM), characterize the upper Quaternary sequences. The geometries of the recognized seismic units indicate as depositional mechanisms were controlled by subsidence and sea-level fluctuations. In detail, deposits related to the last glacia…
Biowaiver monographs for immediate release solid oral dosage forms: quinidine sulfate.
2009
Literature data are reviewed relevant to the decision to allow a waiver of in vivo bioequivalence (BE) testing for the approval of new multisource and reformulated immediate release (IR) solid oral dosage forms containing quinidine sulfate. Quinidine sulfate's solubility and permeability, its therapeutic use and index, pharmacokinetics, excipient interactions and reported BE/bioavailability (BA) problems were taken into consideration. The available data are not fully conclusive, but do suggest that quinidine sulfate is highly soluble and moderately to highly permeable and would likely be assigned to BCS Class I (or at worst BCS III). In view of the inconclusiveness of the data and, more imp…
Requirement of Retinoic Acid Receptor Isotypes α, β, and γ during the Initial Steps of Neural Differentiation of PCC7 Cells
2005
Retinoic acid (RA) is indispensable for morphogenesis and differentiation of several tissues, including the nervous system. The requirement of the RA receptor (RAR) isotypes alpha, beta, and gamma and the putative role of retinoid X receptor-(RXR) signaling in RA-induced neural differentiation, was analyzed. For this compound-selective retinoids and the murine embryonal carcinoma cell line PCC7, a model system for RA-dependent neural differentiation was used. The present paper shows that proliferating PCC7 cells primarily express RXRalpha and RARalpha, lower levels of RXRbeta, and barely detectable amounts of RARbeta, RARgamma, and RXRgamma. At receptor-selective concentrations, only a RARa…
In vivo Trafficking and Localization of p24 Proteins in Plant Cells
2008
p24 proteins constitute a family of putative cargo receptors that traffic in the early secretory pathway. p24 proteins can be divided into four subfamilies (p23, p24, p25 and p26) by sequence homology. In contrast to mammals and yeast, most plant p24 proteins contain in their cytosolic C-terminus both a dilysine motif in the -3, -4 position and a diaromatic motif in the -7, -8 position. We have previously shown that the cytosolic tail of Arabidopsis p24 proteins has the ability to interact with ARF1 and coatomer (through the dilysine motif) and with COPII subunits (through the diaromatic motif). Here, we establish the localization and trafficking properties of an Arabidopsis thaliana p24 pr…
Structural Change in the education system in Algeria and economic overhaul
2015
Evoking the problem of the relationship between the emerging economies that were still in training with the educational strategy in the case of a country may be colonized in the economy and school structures are staked, allowed us to these operations to repair Messaging standards and strategies that determine the economic and educational options, namely time and touches to a country that was in originally builds himself.There lies the issue which is namely the analysis of correlation between economic growth and basic knowledge of factors. And displays numbers and statistics that measure the amount of these factors in the analysis and development of public investment in education and trainin…
ZFWD: a novel subfamily of plant proteins containing a C3H zinc finger and seven WD40 repeats
2000
We describe a new subfamily of WD repeat proteins characterised by the presence of a C3H zinc finger at the N-terminal part of the protein associated with seven WD40 repeats. We have identified four members of this subfamily in Arabidopsis thaliana, one of them with associated expressed sequence tags (ESTs). We have also identified homologous ESTs in rice, cotton, maize, poplar, pine tree and the ice plant. We do not observe animal homologues, suggesting that this subfamily could be specific for plants. Our data suggest an important role for these proteins. Based on the high sequence conservation within the conserved domains, we suggest that these proteins could have a regulatory function.
Pathogenesis and molecular mechanisms of anderson–fabry disease and possible new molecular addressed therapeutic strategies
2021
Anderson–Fabry disease (AFD) is a rare disease with an incidenceof approximately 1:117,000 male births. Lysosomal accumulation of globotriaosylceramide (Gb3) is the element characterizing Fabry disease due to a hereditary deficiency α-galactosidase A (GLA) enzyme. The accumulation of Gb3 causes lysosomal dysfunction that compromises cell signaling pathways. Deposition of sphingolipids occurs in the autonomic nervous system, dorsal root ganglia, kidney epithelial cells, vascular system cells, and myocardial cells, resulting in organ failure. This manuscript will review the molecular pathogenetic pathways involved in Anderson–Fabry disease and in its organ damage. Some studies reported that i…
Climatic oscillations triggered post-Messinian speciation of Western Palearctic brown frogs (Amphibia, Anura, Ranidae)
2003
Abstract Oscillating glacial cycles over the past 2.4 million years are proposed to have had a major impact on the diversity of contemporary species communities. We used mitochondrial and nuclear DNA sequence data to infer phylogenetic relationships within Western Palearctic brown frogs and to test the influence of Pliocene and Pleistocene climatic changes on their evolution. We sequenced 1976 bp of the mitochondrial genes 16S rRNA and cytochrome b and of the nuclear rhodopsin gene for all current species and subspecies. Based on an established allozyme clock for Western Palearctic water frogs and substitution rate constancy among water frogs and brown frogs, we calibrated a molecular clock…