Search results for "Formulation"
showing 10 items of 265 documents
An implicit mesh discontinuous Galerkin formulation for higher-order plate theories
2019
In this work, a discontinuous Galerkin formulation for higher-order plate theories is presented. The starting point of the formulation is the strong form of the governing equations, which are derived in the context of the Generalized Unified Formulation and the Equivalent Single Layer approach from the Principle of Virtual Displacements. To express the problem within the discontinuous Galerkin framework, an auxiliary flux variable is introduced and the governing equations are rewritten as a system of first-order partial differential equations, which are weakly stated over each mesh element. The link among neighboring mesh elements is then retrieved by introducing suitably defined numerical …
Pellets based on polyuronates: Relationship between gelation and release properties
2017
International audience; Three polyuronates: amidated low methoxyl pectin (ALMP), low methoxyl pectin (LMP) and polygalacturonic acid (PGA) were used to encapsulate rutin in pellets, and they were characterized by different techniques (macroscopic properties, Calcium and rutin release). The ability of the three polyuronates to bind calcium ions and the viscoelastic properties of gels were performed to relate the properties of the pellets to the gel structures. The pellets size, the water content, the water uptake, the release of calcium and rutin varied depending on the polyuronate used. The pellets size of ALMP were smaller than LMP and PGA with a lower water content, but this matrix was mo…
Practices in research, surveillance and control of neglected tropical diseases by One Health approaches: A survey targeting scientists from French-sp…
2021
One health (OH) approaches have increasingly been used in the last decade in the fight against zoonotic neglected tropical diseases (NTDs). However, descriptions of such collaborations between the human, animal and environmental health sectors are still limited for French-speaking tropical countries. The objective of the current survey was to explore the diversity of OH experiences applied to research, surveillance and control of NTDs by scientists from French-speaking countries, and discuss their constraints and benefits. Six zoonotic NTDs were targeted: echinococcoses, trypanosomiases, leishmaniases, rabies, Taenia solium cysticercosis and leptospiroses. Invitations to fill in an online q…
A Systematic Way of Structuring Real-World Multiobjective Optimization Problems
2023
In recent decades, the benefits of applying multiobjective optimization (MOO) methods in real-world applications have rapidly increased. The MOO literature mostly focuses on problem-solving, typically assuming the problem has already been correctly formulated. The necessity of verifying the MOO problem and the potential impacts of having an incorrect problem formulation on the optimization results are not emphasized enough in the literature. However, verification is crucial since the optimization results will not be meaningful without an accurate problem formulation, not to mention the resources spent in the optimization process being wasted. In this paper, we focus on the MOO problem struc…
Effective reference and current integration for large displacement interface
2016
The most common interface formulations proposed in literature are generally based on the restrictive hypothesis of small strains and small displacements and, even though their application to geometrically nonlinear problems is of paramount interest, only few contributions are available in literature. Motivations are probably due to the difficulties encountered on such formulation, as already mentioned by several authors. A pioneering formulation is the finite displacement three-dimensional interface developed by Ortiz and Pandolfi in [1], where normal and tangential traction components are evaluated with respect to the middle surface in the current configuration, producing a non-symmetric g…
Predicting response to interpersonal counselling (IPC) from case formulation : a systematic comparison between recovered and unchanged depressive cas…
2019
We sought to explore how the process between the counsellor and patient for arriving at a case formulation may predict the outcome of manualized interpersonal counselling (IPC) for depression in primary care. Qualitative content analysis and applied conversation analysis (CA) were used to achieve depth in the understanding of case formulation process among five patients who recovered and five who were unchanged according to quantitative post-treatment change rates derived from Clinical Outcomes in Routine Evaluation– Outcome Measure (CORE-OM). Interaction in the case formulations for the recovered group was generally characterized by a joint construction effort between the counsellor and th…
Primary extranodal non-Hodgkin lymphomas of the uterus and the breast: report of three cases
1995
The authors describe one case of a rare primitive non-Hodgkin lymphoma of the uterus, and two cases of primary non-Hodgkin lymphoma of the breast. Histologically, the uterine lymphoma, although clinically confined to the uterus, was a diffuse large cell lymphoma, group G according to the Working formulation for Clinical Usage. The two cases of breast lymphoma were a centrocytic-centroblastic and a lymphoplasmocytoid non-Hodgkin lymphoma, respectively. All cases were initally treated with radical surgery plus radiotherapy, but the first patient showed an early recurrence at distant sites, which required systemic cytotoxic chemotherapy. The patient with uterine non-Hodgkin lymphoma received a…
The Potential Use of Resveratrol for Cancer Prevention.
2019
In addition to the traditional treatments of cancer and cancer prevention, the use of natural compounds, especially those found in food, should be considered. To clarify if resveratrol has the potential for cancer prevention and the possibility of use in therapy, the following must be taken into account: data from epidemiology, clinical protocol (case and control), preclinical studies (lab animals), use of established cell lines as models of cancer cells, test tube assays (enzymes activities), and requirements of nanotechnologies in order to discover new drugs to fight cancer. From this perspective and future expected advances, more information is needed such as improved efficacy, methods o…
Assessment of the Inter-Batch Variability of Microstructure Parameters in Topical Semisolids and Impact on the Demonstration of Equivalence
2019
Demonstration of similar microstructure is essential for demonstrating the equivalence of generic topical products since the microstructure of semisolids may affect the drug release. The objective of this study was to compare the microstructure-defining physical parameters of different batches of a reference ointment containing calcipotriol and betamethasone (Daivobet 50 µ
La circulation des termes dans le discours médiatique : peut-on informer sans déformer ?
2016
Media diversification and information superhighways that have become faster and faster have boosted the circulation of economic terms in the popular press, along with the interaction between editorial contents targeted at the general population, which are similar in nature. This twin phenomenon of circulation and interaction was highlighted in a contrastive study of the way the German and the French press managed the euro crisis between 2011 and 2013: articles devoted to the debt of countries that are going through hard economic times require expert knowledge, but also resort to popularization strategies that show multi-level interdiscursivity.