Search results for "FrACT"

showing 10 items of 6229 documents

Posterior chamber phakic intraocular lenses to correct high myopia: A comparative study between Staar and Adatomed models

2001

ABSTRACT PURPOSE: To determine the feasibility of using posterior chamber phakic intraocular lenses (PIOLs) to treat high myopia, comparing two different models, Staar and Adatomed. METHODS: Twenty-four eyes from 12 patients were studied prospectively. A phakic Staar IOL was implanted in one eye of each patient, and the other eye received a phakic Adatomed IOL. Patients with uveitis or ocular trauma prior to ocular surgery, diabetic retinopathy, or capsular pseudoexfoliation were excluded. The mean preoperative spherical equivalent refraction was -16.00 ± 5.05 D for the Staar group and -15.39 ± 2.83 D for the Adatomed group. Average follow-up was 32.4 months (range, 19 to 46 mo) for the Ada…

AdultMaleIntraocular pressureRefractive errormedicine.medical_specialtyAnterior subcapsular cataractVisual acuitygenetic structuresEye diseasemedicine.medical_treatmentLens Capsule CrystallineVisual AcuityIntraocular lensRefraction OcularPhakic intraocular lensCataractVision disorderPostoperative ComplicationsForeign-Body MigrationLens Implantation IntraocularLens CrystallineMyopiaHumansMedicineIntraocular PressureLenses Intraocularbusiness.industrymedicine.diseaseeye diseasesSurgeryOphthalmologyFeasibility StudiesFemaleSurgerysense organsmedicine.symptombusinessFollow-Up Studies
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Medium-term visual, refractive, and intraocular stability after implantation of a posterior chamber phakic intraocular lens to correct moderate to hi…

2011

To evaluate the medium-term refractive and visual outcomes and the complications after implantation of a silicone posterior chamber phakic intraocular lens (PC pIOL) for moderate to high myopia.Oftalmar, Medimar International Hospital, Alicante, Spain.Retrospective case series.Uncorrected (UDVA) and corrected (CDVA) distance visual acuities, refraction, and intraocular pressure were evaluated during a medium-term follow-up. Postoperative complications were also studied.The study enrolled 35 eyes (mean preoperative spherical equivalent [SE] -10.25 diopters [D] ± 3.19 [SD]) of 20 patients with a mean age of 31.83 ± 8.87 years and a mean follow-up of 57.34 ± 9.24 months. The mean UDVA improved…

AdultMaleIntraocular pressuremedicine.medical_specialtyPhakic Intraocular LensesVisual acuitygenetic structuresVisual AcuityPhakic intraocular lensRefraction OcularMedium termYoung AdultPostoperative ComplicationsLens Implantation IntraocularOphthalmologyMedicineHumansDioptreIntraocular PressureRetrospective Studiesbusiness.industryHigh myopiaPosterior Eye SegmentMiddle AgedRefractioneye diseasesSensory SystemsPosterior chamber phakic intraocular lensOphthalmologyTreatment OutcomeMyopia DegenerativeSurgeryFemalemedicine.symptombusinessFollow-Up StudiesJournal of cataract and refractive surgery
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Intraocular pressure after excimer laser myopic refractive surgery

2001

The aim of this study was to determine whether intraocular pressure (IOP), as measured by Goldmann applanation or non-contact tonometry, shows systematic changes in patients who have undergone photorefractive keratectomy (PRK) or laser in situ keratomileusis (LASIK). IOP was measured by central Goldmann and non-contact tonometry in 54 patients pre and post-PRK, and in 43 patients pre- and post-LASIK. An interval of 12 months was allowed after surgery. Patients were selected to have one of four specific initial values of refractive error (-2.5, -5.0, -7.5 and -10.0 D). Fellow unoperated eyes were used as controls. A paired Student's t-test and a one-way ANOVA test were used for statistical a…

AdultMaleIntraocular pressuremedicine.medical_specialtyRefractive errorgenetic structuresmedicine.medical_treatmentEye diseaseKeratomileusis Laser In SituContext (language use)KeratomileusisPhotorefractive KeratectomySensitivity and SpecificityTonometry OcularRefractive surgeryOphthalmologyMyopiamedicineHumansIntraocular PressureAnalysis of Variancebusiness.industryLASIKmedicine.diseaseeye diseasesSensory SystemsPhotorefractive keratectomySurgeryOphthalmologyFemaleLasers Excimersense organsbusinessOptometryOphthalmic and Physiological Optics
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Corneoscleral contact lenses for visual rehabilitation after keratoplasty surgery.

2019

Abstract Purpose To report the use of corneoscleral lenses (CSL) in keratoconus patients who were unsatisfied with their visual outcomes after keratoplasty surgery. Methods Eleven consecutive cases with unsatisfactory vision with spectacles, due to irregular astigmatism, preferred to try CSL before SL due to handling or economic issues. An eye examination included refraction and visual acuity assessment, anterior eye biomicroscopy, ocular fundus examination, corneal topographic analysis, endothelial-cell count (ECC) and evaluation of corneal biomechanical parameters (corneal resistance factor, CRF; corneal hysteresis, CH; corneal-compensated intraocular pressure, IOPcc). The fitting process…

AdultMaleKeratoconusIntraocular pressuremedicine.medical_specialtyVisual acuitygenetic structuresContact LensesVisual rehabilitationKeratoconusRefraction Ocularlaw.inventionCorneal hysteresisCorneal Transplantation03 medical and health sciences0302 clinical medicinelawmedicineHumansAgedRetrospective StudiesAged 80 and overKeratometerIrregular astigmatismmedicine.diagnostic_testbusiness.industryAstigmatismCorneal TopographyGeneral MedicineMiddle Agedmedicine.diseaseeye diseasesSurgeryOphthalmologyEye examination030221 ophthalmology & optometryFemalesense organsmedicine.symptombusiness030217 neurology & neurosurgeryKeratoplasty PenetratingOptometryContact lensanterior eye : the journal of the British Contact Lens Association
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Intrastromal corneal ring segment implantation in paracentral keratoconus with coincident topographic and coma axis.

2012

To evaluate the efficacy, predictability, and safety of implantation of Ferrara-type intrastromal corneal ring segments (ICRS) for refractive correction of paracentral keratoconus.Fernández-Vega Ophthalmological Institute, Oviedo, Spain.Cohort study.Snellen uncorrected (UDVA) and corrected (CDVA) distance visual acuities and residual refractive errors were recorded before and 6 months after ICRS implantation for keratoconus. The tunnels for ICRS implantation were created with a femtosecond laser. The power vector and the Alpins method were used to analyze postoperative refractive outcomes.The study evaluated 56 eyes of 49 patients. The mean UDVA was 0.17 ± 0.14 (SD) preoperatively and 0.41 …

AdultMaleKeratoconusmedicine.medical_specialtygenetic structuresmedicine.medical_treatmentCorneal StromaVision DisordersVisual AcuityComa (optics)Power vectorKeratoconusRefraction OcularCohort StudiesProsthesis ImplantationYoung AdultOphthalmologymedicineHumansPolymethyl MethacrylateProspective StudiesAlpins methodAgedIntrastromal corneal ring segmentbusiness.industryCorneal TopographyProstheses and ImplantsMiddle Agedmedicine.diseaseeye diseasesSensory SystemsSurgeryOphthalmologySurgeryFemalesense organsLaser TherapyCorneal ringbusinessJournal of cataract and refractive surgery
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Subjective Satisfaction in Long-term Orthokeratology Patients

2013

Purpose: To AU3 evaluate the subjective satisfaction in visual stability, night vision complains, and light distortion phenomena, and also the number of hours and days per week of lens wear, in patients with myopia undergoing orthokeratology (OK) treatment for at least 1 year. Methods: A visual analog scale (VAS) questionnaire containing 18 items was administered to 44 patients, 29 women and 15 men (mean age, 24.39 6 9.11 years), with a baseline spherical equivalent refractive error of 22.40 6 0.94 diopters and astigmatism up to 20.5 diopters. Average treatment period by the time of data collection was 19 6 7 months. Patients rated their satisfaction with the correction, with complaints of …

AdultMaleLight distortionVisual acuityAdolescentvisual acuitygenetic structuresmedicine.medical_treatmentSubjective satisfactionRefraction OcularYoung Adult03 medical and health sciences0302 clinical medicineOpticsSurveys and QuestionnairesNight visionHumansMedicineIn patientChildPain Measurement030304 developmental biologyAU6 visual acuity0303 health sciencesScience & Technologybusiness.industryOrthokeratologyMiddle AgedRefractive Errorseye diseasesCorneal refractive therapy3. Good healthTerm (time)OphthalmologyPatient Satisfaction030221 ophthalmology & optometryPatient ComplianceOptometryFemalemedicine.symptomOvernight orthokeratologybusinessOrthokeratologic ProceduresEye & Contact Lens: Science & Clinical Practice
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Light distortion of soft multifocal contact lenses with different pupil size and shape

2020

Purpose: To study the light distortion effects of soft multifocal contact lenses and the influence of different pupil size and shape.Methods: A total of 14 eyes of 7 healthy contact lens users (mean age 28.6 +/- 8.5 years) were recruited. The "Light Disturbance Analyser" device was employed for light characterization. The selected lenses were the monthly disposable "Biofinity multifocal" (CooperVision, CA, USA), both centre-distance and centre-near designs (addition power + 2.50 D). Two circular pupils of 3 mm and 5 mm of diameter, and an elliptical shape (3 horizontal and 5 vertical mm) were used. Metrics such as the light distortion index (LDI), best-fit circle radius and its irregularity…

AdultMaleLight distortionbusiness.product_categorygenetic structuresCiências Naturais::Ciências Físicas:Ciências Físicas [Ciências Naturais]Visual AcuityRefraction OcularPupillaw.invention03 medical and health sciences0302 clinical medicineOpticslawDistortionNon-circular pupilsHumansMultifocal lensesMathematicsScience & Technologybusiness.industryPupil sizePupilMean ageEquipment DesignGeneral MedicineRadiusMiddle AgedContact Lenses HydrophilicRefractive ErrorsHealthy Volunteerseye diseasesContact lensLens (optics)Ophthalmology030221 ophthalmology & optometryMultifocal contact lensesFemalesense organsbusiness030217 neurology & neurosurgeryOptometryContact Lens and Anterior Eye
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Objective measurement of intraocular forward light scatter using Hartmann-Shack spot patterns from clinical aberrometers. Model-eye and human-eye stu…

2007

Purpose To apply software-based image-analysis tools to objectively determine intraocular scatter determined from clinically derived Hartmann-Shack patterns. Setting Aston Academy of Life Sciences, Aston University, Birmingham, United Kingdom, and Department of Optics, University of Valencia, Valencia, Spain. Methods Purpose-designed image-analysis software was used to quantify scatter from centroid patterns obtained using a clinical Hartmann-Shack analyzer (WASCA, Zeiss/Meditec). Three scatter values, as the maximum standard deviation within a lenslet for all lenslets in the pattern, were obtained in 6 model eyes and 10 human eyes. In the model-eye sample, patterns were obtained in 4 sessi…

AdultMaleLightPsychometricsIntraclass correlationLensletDiagnostic Techniques OphthalmologicalEyeRefraction OcularModels BiologicalSensitivity and SpecificityStandard deviationOpticsmedicineImage Processing Computer-AssistedHumansScattering RadiationMathematicsbusiness.industryObjective measurementCentroidReproducibility of ResultsSmall sampleRepeatabilitySensory SystemsOphthalmologymedicine.anatomical_structureOptometrySurgeryHuman eyeFemalebusinessJournal of cataract and refractive surgery
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Accommodative stimulus-response curves to low-pass filtered natural images

2018

To assess how the monocular steady-state accommodative stimulus-response curve is modified when viewing low-pass filtered natural images. Eighteen adult subjects participated in the study. The accommodative stimulus-response curve was objectively assessed by means of a Hartmann-Shack wavefront sensor. Measurements were taken at different accommodative demands. Target images were low-pass filtered versions of a natural image that were obtained applying different digital spatial filters that limited the spatial frequency content of the natural image. Cutoff spatial frequencies were set at 30, 21, and 15 cycles per degree (cy/deg). Mean data obtained for each target were fitted to linear model…

AdultMaleLow-pass filterRefraction Ocular050105 experimental psychologyYoung Adult03 medical and health sciencesCellular and Molecular Neuroscience0302 clinical medicineOpticsVision MonocularLinear regressionMyopiaHumansCutoff0501 psychology and cognitive sciencesMathematicsAnalysis of covarianceMonocularbusiness.industry05 social sciencesLinear modelAccommodation OcularWavefront sensorSensory SystemsOphthalmologySpace Perception030221 ophthalmology & optometryFemaleSpatial frequencybusinessPhotic StimulationGraefe's Archive for Clinical and Experimental Ophthalmology
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Intravenous injection of bortezomib, melphalan and dexamethasone in refractory and relapsed multiple myeloma

2013

Abstract Background A combination of bortezomib (1.3 mg/m2), melphalan (5 mg/m2), and dexamethasone (40 mg) (BMD), with all three drugs given as a contemporary intravenous administration, was retrospectively evaluated. Patients and methods Fifty previously treated (median 2 previous lines) patients with myeloma (33 relapsed and 17 refractory) were assessed. The first 19 patients were treated with a twice-a-week (days 1, 4, 8, 11, ‘base’ schedule) administration while, in the remaining 31 patients, the three drugs were administered once a week (days 1, 8, 15, 22, ‘weekly’ schedule). Results Side-effects were predictable and manageable, with prominent haematological toxicity, and a better tox…

AdultMaleMelphalanmedicine.medical_specialtyDrug-Related Side Effects and Adverse ReactionsSalvage therapyGastroenterologyDexamethasoneDisease-Free SurvivalDrug Administration ScheduleBortezomibRefractoryRecurrenceInternal medicineAntineoplastic Combined Chemotherapy ProtocolsmedicineHumansProgression-free survivalMelphalanMultiple myelomaDexamethasoneAgedRetrospective StudiesAged 80 and overBortezomibbusiness.industryHematologyMiddle Agedmedicine.diseaseBoronic AcidsRegimenTreatment OutcomeOncologyPyrazinesInjections IntravenousFemaleMultiple MyelomabusinessFollow-Up Studiesmedicine.drug
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