Search results for "Fragility"
showing 10 items of 75 documents
Tivoli Amusement Park Tour Guide
2019
The Tivoli Amusement Park is one of the largest amusement parks in the World, the total area is 250 hectares. It includes many attractions, some are very recent and others were made several years ago, but all of them are still able to arouse curiosity and fun for young and old people. Some people says that it's the only 2nd oldest surviving amusement park, untouched until today, after the one of Dyrehavsbakken, near Copenhagen. But these are only rumors, because by visiting the Tivoli Amusement Park it will be possible to undoubtedly remove this thoughts. The Tivoli Amusement Park is divided into 5 large entertainment areas: the Cardo & Decumano, the Aniene Water Park, Villa d'Este, the…
Chimeric amplicons containing the c-myc gene in HL60 cells
1998
The major amplicon present in HL60 cells is chimeric in nature being composed of 70 kb of DNA sequence derived from the MYC locus linked to 80 kb of novel DNA sequence derived from a non contiguous region located telomeric to the c-myc gene at 8q24 (Feo et al., 1996). Here we show by fluorescence in situ hybridization (FISH) that these coamplified sequences, MCR (Myc Coamplified Region), are derived from a locus located 3-4 Mb telomeric to the c-myc gene in the q24.2-24.3 region of chromosome 8. Genomic cloning and Southern blot analysis indicate the arrangement of chimeric amplicons are in tandem arrays. Analysis of the DNA sequences at the juncture of the MYC locus and the MCR suggest tha…
Dynamic thermal expansivity near the glass transition
2000
Dielectric techniques were used to investigate the thermal expansivity of polystyrene films. Capacitive scanning dilatometry (CSD) employs temperature ramping in order to monitor the non-linear structural relaxation in the glass transformation range and to quantify liquid fragility. In the linear response regime, the complex thermal expansivity is obtained as a function of the temperature cycling frequency and is observed to reflect the structural relaxation.
Non-exponential relaxation in disordered materials: Phenomenological correlations and spectrally selective experiments
1998
Abstract In most glass-forming materials external perturbations are relaxed in a non-exponential fashion. It is shown that the degree of non-exponentiality is phenomenologically correlated with the departure from simple thermally activated behavior as measured by the fragility index m. In model glass formers such as the Ge-As-Se ternary alloy, and to some degree for amorphous materials in general, the correlations with these properties are observed also for other characteristic features. These include the specific heat step and the aging kinetics in the glass transformation range. While phenomenological correlations have proven very useful for rationalizing the properties of many glass form…
Financial Fragility and Interacting Units: an Exercise
2010
This paper assumes that financial fluctuations are the result of the dynamic interaction between liquidity and solvency conditions of individual financial units. The framework is designed as a heterogeneous agent model which proceeds through discrete time steps within a finite time horizon. The interaction at the microlevel between financial units and the market maker, who is in charge of clearing the market, produces interesting complex dynamics. The model is analyzed by means of numerical simulations and agent-based computational economics (ACE) approach. The behaviour and evolution of financial units are studied for different parameter regimes in order to show the importance of the param…
Functional Inactivation of pRB Results in Aneuploid Mammalian Cells After Release From a Mitotic Block
2002
AbstractThe widespread chromosome instability observed in tumors and in early stage carcinomas suggests that aneuploidy could be a prerequisite for cellular transformation and tumor initiation. Defects in tumor suppressers and genes that are part of mitotic checkpoints are likely candidates for the aneuploid phenotype. By using flow cytometric, cytogenetic, immunocytochemistry techniques we investigated whether pRB deficiency could drive perpetual aneuploidy in normal human and mouse fibroblasts after mitotic checkpoint challenge by microtubule-destabilizing drugs. Both mouse and human pRB-deficient primary fibroblasts resulted, upon release from a mitotic block, in proliferating aneuploid …
Effect of sisal and hydrothermal ageing on the dielectric behaviour of polylactide/sisal biocomposites
2017
[EN] The dielectric properties of virgin polylactide (PLA) and its reinforced composites with different weight amounts of sisal fibres were assessed at broad temperature (from - 130 degrees C to 130 degrees C) and frequency ranges (from 10(-2)-10(7) Hz), before and after being subjected to accelerated hydrothermal ageing. The synergetic effects of both the loading of sisal and hydrothermal ageing were analysed by means of dielectric relaxation spectra. The relaxation time functions were evaluated by the Havriliak-Negami model, substracting the ohmic contribution of conductivity. The intramolecular and intermolecular relaxations were respectively analysed by means of Arrhenius and Vogel-Fulc…
Meeting the challenges of the 21st century: Social change and the family
2020
The article recounts major changes in the European family and challenges it creates in accounting and supporting families. Fragility and diversity of family relationships, individualization and shrinking size of households are seen both as a result of change in the system of values and the processes of economics. Statistical tools used to assess the family dynamics increasingly become inadequate to monitor and interpret the change and situation in families. Statistical figures also construct the way families are imagined in policies. Fertility, marriage and divorce rates are connected to reproductive functions of the society while employment figures feature the productive needs in societies…
Financial Fragility and Distress Propagation in a Network of Regions
2012
Building on previous works on business fluctuations, we model the propagation of financial distress in a network of regions, each populated by heterogeneous interacting firms and banks. In order to diversify risk, firm sell goods outside their own region and borrow from banks located there. However, this results in ties across regions which propagate financial distress across regional borders. We investigate how the average level of economic integration affects the probability of both individual and systemic failures. We find that the benefit of greater diversification is eventually offset by the effect of financial acceleration and contagion. In particular, beyond a certain level of integr…
Bank fragility and contagion: Evidence from the bank CDS market
2016
Understanding how contagion works among financial institutions is a top priority for regulators and policy makers who aim to foster financial stability and to prevent financial crises. Using bank credit default swap (CDS) data, we provide a framework for the evaluation of contagion among banks in different countries and regions during a period of prolonged financial distress. We measure contagion in terms of return spillovers, following a Generalized VAR (GVAR) approach. In addition, we propose an innovative framework to distinguish between two types of contagion: systematic (linked to global factors), and idiosyncratic (linked to bank specific factors). We find evidence of both types of co…