Search results for "Frail Elderly"

showing 10 items of 165 documents

Delayed postural control during self-generated perturbations in the frail older adults

2012

Alexandre Kubicki1–3, François Bonnetblanc1,2, Geoffroy Petrement3, Yves Ballay1,2, France Mourey2,4¹UFR STAPS, Université de Bourgogne, Dijon, France; ²Motricité et Plasticité, Institut National de la Santé et de la Recherche Médicale (INSERM), Dijon, France; ³SARL Fovea Interactive, Campus Industriel – Espace Entreprises, Chalon sur Saône, France; 4UFR Médecine, Université de Bourgogne, Dijon, FrancePurpose: The aim of this study was to investigate the coordination between posture and movement in pathological aging (frailty) in comparison with no…

MaleMovement disordersbackward disequilibriumPoison controlKinematicsPHENOTYPEPostural control0302 clinical medicineCognitionCenter of pressure (terrestrial locomotion)Task Performance and AnalysisPostural BalanceARM MOVEMENTAttention030212 general & internal medicineanticipatory postural adjustmentsPostural BalanceOriginal ResearchAged 80 and overMovement DisordersFALLSCognitionGeneral MedicineAdaptation PhysiologicalBackward Disequilibrium.COMMUNITYPROBABILITYADJUSTMENTSOlder adults[ SCCO.NEUR ] Cognitive science/NeuroscienceArmELDERLY PERSONSFemalemedicine.symptommedicine.medical_specialtyGO TESTFrail ElderlyFrail Older AdultsPosturefrailtyAGE-RELATED-CHANGES03 medical and health sciencesPhysical medicine and rehabilitationmedicineReaction TimeHumansAgedbusiness.industry[SCCO.NEUR]Cognitive science/Neuroscience[SCCO.NEUR] Cognitive science/NeuroscienceRC952-954.6Postural controlGeriatricsClinical Interventions in AgingGeriatrics and Gerontologybusiness030217 neurology & neurosurgeryPsychomotor PerformanceClinical Interventions in Aging
researchProduct

Response to Vidal and Colleagues

2015

MaleOxidative StressCross-Sectional StudiesPsychoanalysisbusiness.industryFrail ElderlyHumansProteinsMedicineFemaleGeriatrics and GerontologyLipid MetabolismbusinessJournal of the American Geriatrics Society
researchProduct

Longitudinal Association Between Physical Activity and Frailty Among Community-Dwelling Older Adults

2020

Objectives: To examine the longitudinal association between frequency of moderate physical activity (PA) and overall, physical, psychological, and social frailty among community-dwelling older adults older than 70 years. Second, we assessed the association between a 12-month change in frequency of moderate PA and frailty. Design: Longitudinal cohort study. Setting: Community settings in Spain, Greece, Croatia, the Netherlands, and the United Kingdom. Participants: A total of 1735 participants (61.1% female ; mean age = 79.6 years ; SD = 5.5 years). Measurements: The frequency of self-reported moderate PA was measured and classified into two categories: "regular frequency" and "low frequency…

MaleRegular Issue ContentFrail ElderlyPhysical activityClinical Investigationsphysical activityfrailtyphysical frailty03 medical and health sciences0302 clinical medicineBIOMEDICINA I ZDRAVSTVO. Javno zdravstvo i zdravstvena zaštita.Regular frequencySurveys and QuestionnairesMedicineHumanssocial frailty.030212 general & internal medicineClinical InvestigationLongitudinal StudiesLongitudinal cohortAssociation (psychology)Setting communityExerciseAgedbusiness.industryBIOMEDICINE AND HEALTHCARE. Public Health and Health Care.Mean ageConfidence intervalEuropefrailty ; physical activity ; physical frailty ; psychological frailty ; social frailty.psychological frailtyFemaleIndependent LivingSelf ReportGeriatrics and Gerontologysocial frailtybusiness030217 neurology & neurosurgeryDemographyJournal of the American Geriatrics Society
researchProduct

Depressed mood and body mass index as predictors of muscle strength decline in old men

2000

OBJECTIVE: To study depressed mood as a predictor of strength decline within body weight categories over a 3-year follow-up period. DESIGN: A prospective cohort study over 3 years. SETTING: Honolulu, Hawaii. PARTICIPANTS: The subjects were 2275 men participating in the Honolulu Heart Program with an average age of 77.1 years (range 71–92 years), who were not cognitively impaired at baseline (Exam 4), and who participated in maximal hand grip strength measurements at baseline and 3 years later (Exam 5). MEASUREMENTS: Hand grip strength was measured using a dynamometer. Depressive symptoms were studied using an 11-item version of Center for Epidemiologic Studies Depression Scale with 9 as a c…

MaleRiskmedicine.medical_specialtyFrail ElderlyComorbidityOverweightHawaiiBody Mass IndexGrip strengthmedicineOdds RatioHumansProspective StudiesProspective cohort studyDepression (differential diagnoses)AgedAged 80 and overMuscle WeaknessHand Strengthbusiness.industryDepressionOdds ratioCenter for Epidemiologic Studies Depression ScaleCase-Control StudiesPhysical therapyGeriatrics and Gerontologymedicine.symptomUnderweightbusinessBody mass indexDemography
researchProduct

The impact of frailty on ICU and 30-day mortality and the level of care in very elderly patients (≥ 80 years)

2017

Purpose: Very old critical ill patients are a rapid expanding group in the ICU. Indications for admission, triage criteria and level of care are frequently discussed for such patients. However, most relevant outcome studies in this group frequently find an increased mortality and a reduced quality of life in survivors. The main objective was to study the impact of frailty compared with other variables with regards to short-term outcome in the very old ICU population. Methods: A transnational prospective cohort study from October 2016 to May 2017 with 30 days follow-up was set up by the European Society of Intensive Care Medicine. In total 311 ICUs from 21 European countries participated. Th…

MaleTime FactorsOutcome AssessmentFrail Elderly/statistics & numerical data[SDV]Life Sciences [q-bio]HSJ UCIPassiveCritical Care and Intensive Care MedicineFrailty/classification/diagnosis/mortality/therapySeverity of Illness IndexSeverity of illneElderly0302 clinical medicineQuality of lifeElderly; Frailty; ICU; Mortality; Octogenarians; Severity of illness; Aged 80 and over; Critical Illness; Europe; Euthanasia Passive; Female; Frail Elderly; Frailty; Geriatric Assessment; Humans; Intensive Care Units; Length of Stay; Male; Outcome Assessment Health Care; Proportional Hazards Models; Prospective Studies; Quality of Life; Severity of Illness Index; Time Factors; Hospital MortalityOutcome Assessment Health Care80 and overProspective StudiesHospital Mortality030212 general & internal medicineProspective cohort studyAged 80 and overeducation.field_of_studyddc:617FrailtyMortality rate[SDV] Life Sciences [q-bio]EuropeIntensive Care UnitsLength of Stay/statistics & numerical dataCohortIntensive Care Units/statistics & numerical dataCritical IllneFemaleSOFA scoreHumanmedicine.medical_specialtyOctogenariansTime FactorCritical IllnessFrail ElderlyIntensive Care UnitPopulationINTENSIVE-CARESeverity of illnessEurope/epidemiologyOutcome Assessment (Health Care)03 medical and health sciencesOctogenarianIntensive careSeverity of illnessJournal ArticlemedicineHumansCOHORTMortalityOctogenarinansIntensive care medicineeducationGeriatric AssessmentAgedProportional Hazards ModelsOLDEREuthanasiabusiness.industry030208 emergency & critical care medicineLength of StayEuthanasia PassiveHealth CareProspective StudieCritical Illness/mortalityUNITICUEmergency medicineProportional Hazards ModelQuality of LifebusinessIntensive Care Medicine
researchProduct

Early life stress and frailty in old age: the Helsinki birth cohort study

2018

Background: Evidence suggests that early life stress (ELS) may extend its effect into adulthood and predispose an individual to adverse health outcomes. We investigated whether wartime parental separation, an indicator of severe ELS, would be associated with frailty in old age. Methods: Of the 972 participants belonging to the present sub-study of the Helsinki Birth Cohort Study, 117 (12. 0%) had been evacuated abroad unaccompanied by their parents in childhood during World War II. Frailty was assessed at a mean age of 71 years according to Fried's criteria. Results: Thirteen frail men (4 separated and 9 non-separated) and 20 frail women (2 separated and 18 non-separated) were identified. C…

MaleWorld War IImedicine.medical_treatmentEarly life stresslcsh:GeriatricsPHENOTYPE3124 Neurology and psychiatryCohort Studies0302 clinical medicineMALTREATMENT030212 general & internal medicineChildFinlandDepression (differential diagnoses)Aged 80 and overRehabilitationFrailtyConfoundingriskitekijätDEPRESSIONPREVALENCE5141 SociologyLife course approachFemaleHEALTHBirth cohortResearch ArticleSEX-DIFFERENCES515 Psychologylife-courseFrail Elderlyearly life stressfrailty03 medical and health sciencesINFLAMMATIONLife-courseterveysvaikutuksetmedicineHumansRisk factornatural experimentAgedADVERSE CHILDHOOD EXPERIENCESbusiness.industryDISABILITY3112 NeurosciencesADULTSstressiEarly life stresslapsuuslcsh:RC952-954.63121 General medicine internal medicine and other clinical medicineRelative risksotalapsetRisk factorGeriatrics and GerontologyNatural experimentbusinessStress Psychological030217 neurology & neurosurgeryFollow-Up StudiesDemographyBMC Geriatrics
researchProduct

Environmental barriers, person-environment fit and mortality among community-dwelling very old people

2013

Background. Environmental barriers are associated with disability-related outcomes in older people but little is known of the effect of environmental barriers on mortality. The aim of this study was to examine whether objectively measured barriers in the outdoor, entrance and indoor environments are associated with mortality among community-dwelling 80- to 89-year-old single-living people. Methods. This longitudinal study is based on a sample of 397 people who were single-living in ordinary housing in Sweden. Participants were interviewed during 2002–2003, and 393 were followed up for mortality until May 15, 2012. Environmental barriers and functional limitations were assessed with the Hous…

Malekuolleisuusmedicine.medical_specialtyLongitudinal studyympäristöFrail Elderlyyksilö-ympäristö yhteensopivuusEnvironmentStairsEnvironmental healthEpidemiologymedicineHumansENABLE AGE-projectMobility LimitationMortalityEnablerProportional Hazards ModelsAged 80 and overSwedenbusiness.industryProportional hazards modelPublic healthPublic Health Environmental and Occupational HealthArchitectural AccessibilityPublic Health Global Health Social Medicine and EpidemiologyHousing for the ElderlyHousing EnablerPerson–environment fitHousingFemaleHousing for the ElderlyBiostatisticsOlder peoplebusinessResearch Article
researchProduct

Effect of 12-Month Supervised, Home-Based Physical Exercise on Functioning Among Persons With Signs of Frailty: A Randomized Controlled Trial

2021

To investigate the effects of a 12-month home-based exercise program on functioning and falls among persons with signs of frailty.A randomized controlled trial with a 1:1 allocation.Home-based.Home-dwelling persons aged 65 years or older meeting at least 1 frailty phenotype criteria (N=300). The mean age of the participants was 82.2±6.3 years, 75% were women, 61% met 1-2 frailty criteria, and 39% met ≥3 criteria.A 12-month, individually tailored, progressive, and physiotherapist-supervised physical exercise twice a week (n=150) vs usual care (n=149).FIM, Short Physical Performance Battery (SPPB), handgrip strength, instrumental activities of daily living (IADL), and self-reported falls and …

Malemedicine.medical_specialtyActivities of daily livingFrail Elderlymedicine.medical_treatmentPoison controlPhysical Therapy Sports Therapy and RehabilitationPhysical exerciselaw.invention03 medical and health sciences0302 clinical medicineRandomized controlled triallawInterquartile rangeInjury preventionmedicineHumans030212 general & internal medicineAgedAged 80 and overRehabilitationFrailtybusiness.industryRehabilitationHome Care ServicesConfidence intervalExercise TherapyPhysical therapyAccidental FallsFemalebusinesshuman activities030217 neurology & neurosurgeryArchives of Physical Medicine and Rehabilitation
researchProduct

Statin Treatment and Prognosis of Elderly Patients Discharged after Non-ST Segment Elevation Acute Coronary Syndrome

2019

<b><i>Background:</i></b> Statins are recommended for secondary prevention. Our aims were to describe the proportion of very elderly patients receiving statins after non-ST segment elevation acute coronary syndrome (NST-ACS) and to determine the prognostic implications of statins use. <b><i>Methods:</i></b> This prospective registry was performed in 44 hospitals that included patients ≥80 years discharged after a NST-ACS from April 2016 to September 2016. <b><i>Results:</i></b> We included 523 patients, the mean age was 84.2 ± 4.0 years and 200 patients (38.2%) were women. Previous statin treatment was recorded in 282 p…

Malemedicine.medical_specialtyAcute coronary syndromeFrail ElderlyAncianoEnfermedad cardiovascularComorbidity030204 cardiovascular system & hematologyTratamiento médico03 medical and health scienceschemistry.chemical_compound0302 clinical medicineInternal medicineEnfermos cardíacosmedicineHumansST segmentPharmacology (medical)Prospective StudiesRegistriesAcute Coronary SyndromeNon-ST Elevated Myocardial InfarctionAged 80 and overLdl cholesterolSecondary preventionbusiness.industryMean ageCholesterol LDLStatin treatmentPrognosismedicine.diseaseComorbidityPatient DischargechemistrySpain030220 oncology & carcinogenesisLow-density lipoproteinFemalelipids (amino acids peptides and proteins)Hydroxymethylglutaryl-CoA Reductase InhibitorsCardiology and Cardiovascular MedicinebusinessAncianosFollow-Up StudiesCardiology
researchProduct

Usefulness of Clinical Data and Biomarkers for the Identification of Frailty After Acute Coronary Syndromes

2015

Abstract Background Frailty predicts mortality after acute coronary syndrome (ACS). The standard frailty scales, such as the Fried score, consist of a variety of questionnaires and physical tests. Our aim was to investigate easily available clinical data and blood markers to predict frailty at discharge, in elderly patients after ACS. Methods A total of 342 patients older than 65 years, survivors after ACS, were included. A high number of clinical variables were collected. In addition, blood markers potentially linked to frailty and related to the processes of inflammation, coagulation, hormonal dysregulation, nutrition, renal dysfunction, and heart dysfunction were determined. Frailty was …

Malemedicine.medical_specialtyAcute coronary syndromeFrail ElderlyMyocardial InfarctionComorbidityDiseaseCohort StudiesRisk FactorsInternal medicineVitamin D and neurologyHumansMedicineMyocardial infarctionAcute Coronary SyndromeCystatin CVitamin DGeriatric AssessmentAgedAged 80 and overbusiness.industryPrognosismedicine.diseaseComorbidityPatient DischargeSurgeryPatient Outcome AssessmentHeart failureHemoglobinometryBiomarker (medicine)FemaleCardiology and Cardiovascular MedicinebusinessBiomarkersFollow-Up StudiesCohort studyCanadian Journal of Cardiology
researchProduct