Search results for "Frail Elderly"

showing 10 items of 165 documents

How should I treat a DeBakey type I acute aortic dissection four weeks after transcatheter aortic valve implantation in an old, fragile patient?

2015

Aged 80 and overAortic dissectionmedicine.medical_specialtyCardiopulmonary BypassTranscatheter aorticbusiness.industryFrail ElderlyEndovascular ProceduresAortic Valve Stenosismedicine.diseaseAortic AneurysmTranscatheter Aortic Valve ReplacementAortic DissectionPostoperative ComplicationsAcute DiseasemedicineHumansFemaleVascular GraftingRadiologyCardiology and Cardiovascular MedicinebusinessAortaEuroIntervention
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Constant Hierarchic Patterns of Physical Functioning Across Seven Populations in Five Countries

1998

This research was aimed at identifying critical steps in the decline in physical function that often parallels aging. Six basic and nine instrumental activities of daily living (ADLs) were classified into four domains of disability characterized by specific underlying physical impairment. The hierarchical order of this classification was verified in two random samples representative of the older home-dwelling population. The concordance level of disability and results of performance-based measures of physical function were also tested. Finally, the cross-cultural reliability of the model was verified in seven population-based samples of older persons living in five European countries. In ol…

Aged 80 and overCross-Cultural ComparisonGerontologyAnalysis of Varianceeducation.field_of_studyActivities of daily livingFrail ElderlyHealth StatusConcordancePopulationReproducibility of ResultsGeneral MedicineMiddle AgedPhysical functionEuropePhysical functioningActivities of Daily LivingHumansGeneral patternGeriatrics and GerontologyFactor Analysis StatisticaleducationPsychologyGerontologyAgedThe Gerontologist
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Immune Alterations in Frailty Syndrome and Cognitive Impairment.

2020

Aged 80 and overImmunity CellularFrailtybusiness.industryEndocrinology Diabetes and MetabolismFrail ElderlyFrailty syndromemedicine.diseaseImmune systemRisk FactorsImmunologyImmunology and AllergyMedicineHumansCognitive DysfunctionCognitive impairmentbusinessAgedEndocrine, metabolicimmune disorders drug targets
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Open mini-invasive cholecystectomy in high risk elderly. A review of 121 consecutive procedures.

2011

INTRODUCTION: the report describes the features of a low cost, open mini-invasive procedure for cholecystectomy in a sample of 121 consecutive high risk elderly (ASA score 3 to 5). PATIENTS AND METHODS: the surgery is performed through a 3 - 4 cm right subcostal skin incision. An optimal exposition of the operating field was achieved thanks to an innovative three valve retractor. RESULTS: a mean hospital stay of 3,02 days, low complication rate and 2,4% mortality are the results of the described procedure. CONCLUSIONS: in high risk elderly the results are extremely encouraging, particularly in comparison with both laparoscopic and traditional open cholecystectomy. The open minisurgical chol…

Aged 80 and overMaleLaparotomyTime FactorsCost-Benefit AnalysisFrail ElderlyLength of StayMiddle AgedRisk AssessmentRadiographySettore MED/18 - Chirurgia GeneraleTreatment OutcomeCholecystectomy LaparoscopicCholelithiasisRisk FactorsHumansMinimally Invasive Surgical ProceduresCholecystectomyFemaleopen mini-invasive cholecystectomyAgedRetrospective Studies
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Frailty and incident depression in community-dwelling older people: results from the ELSA study

2016

Objective: Frailty and pre-frailty are two common conditions in the older people, but whether these conditions could predict depression is still limited to a few longitudinal studies. In this paper, we aimed to investigate whether frailty and pre-frailty are associated with an increased risk of depression in a prospective cohort of community-dwelling older people. Methods: Four thousand seventy-seven community-dwelling men and women over 60 years without depression at baseline were included from the English Longitudinal Study of Ageing. Frailty status was defined according to modified Fried's criteria (weakness, weight loss, slow gait speed, low physical activity and exhaustion) and categor…

Aged 80 and overMaleRiskDepressive DisorderFrail Elderlycommunity-dwelling adultscommunity-dwelling adultfrailtyolder peoplePsychiatry and Mental HealthCommunity-dwelling adults; Depression; Frailty; Older people; Geriatrics and Gerontology; Psychiatry and Mental HealthdepressionOdds RatioHumansFemaleLongitudinal StudiesProspective StudiesGeriatrics and GerontologyExerciseAged
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[Dermatological quality of life in community-dwelling frail elderly people].

2016

Aged 80 and overMaleSpainFrail ElderlyCartas al EditorPrevalenceQuality of LifeHumansFemaleIndependent LivingSkin DiseasesAgedAtencion primaria
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Assessment of Physical Fitness and Risk Factors for the Occurrence of the Frailty Syndrome among Social Welfare Homes’ Residents over 60 Years of Age…

2022

The study aimed at assessing physical fitness and occurrence of the frailty syndrome among social welfare homes’ residents as well as defining factors which determine the level of frailty and its occurrence. The examination included 198 residents (115 females and 83 males of average age 75.5 ± 10.21) and was carried out with the use of the Short Physical Performance Battery (SPPB) test with the following cut-off points: 0–6—frail, 7–9—pre-frail, 10–12—non-frail. The research additionally collected data regarding age, gender, number of chronic diseases, education level, type of prior work and current physical activity. In addition, the height …

Aged 80 and overMaleaging; physical functional performance; nursing homes; frailty syndrome; physical fitness; gait analysisFrailtyFrail ElderlyHealth Toxicology and MutagenesisagingPublic Health Environmental and Occupational HealthMiddle Agednursing homesphysical functional performancefrailty syndromeCross-Sectional StudiesRisk Factorsgait analysisphysical fitnessHumansFemalePolandGeriatric AssessmentSocial WelfareAgedInternational Journal of Environmental Research and Public Health
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Clinical pathways for fragility fractures of the pelvic ring: personal experience and review of the literature

2014

AbstractFragility fractures of the pelvic ring (FFP) are increasing in frequency and require challenging treatment. A new comprehensive classification considers both fracture morphology and degree of instability. The classification system also provides recommendations for type and invasiveness of treatment. In this article, a literature review of treatment alternatives is presented and compared with our own experiences. Whereas FFP Type I lesions can be treated conservatively, FFP Types III and IV require surgical treatment. For FFP Type II lessions, percutaneous fixation techniques should be considered after a trial of conservative treatment. FFP Type III lesions need open reduction and in…

Aged 80 and overmedicine.medical_specialtybusiness.industryFrail Elderlymedicine.medical_treatmentReview ArticleSurgeryScrew fixationFracture Fixation InternalFractures BoneExternal fixationSacroiliac screwPelvic ringFracture fixationOrthopedic surgeryCritical PathwaysmedicinePercutaneous fixationHumansInternal fixationSurgeryOrthopedics and Sports MedicinePelvic BonesbusinessAgedJournal of Orthopaedic Science
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Implementing Precision Medicine in Human Frailty through Epigenetic Biomarkers

2021

The main epigenetic features in aging are: reduced bulk levels of core histones, altered pattern of histone post-translational modifications, changes in the pattern of DNA methylation, replacement of canonical histones with histone variants, and altered expression of non-coding RNA. The identification of epigenetic mechanisms may contribute to the early detection of age-associated subclinical changes or deficits at the molecular and/or cellular level, to predict the development of frailty, or even more interestingly, to improve health trajectories in older adults. Frailty reflects a state of increased vulnerability to stressors as a result of decreased physiologic reserves, and even dysregu…

AgingFrail ElderlyHealth Toxicology and Mutagenesisnon-coding RNAlcsh:MedicineReviewBioinformaticsEpigenesis Genetic03 medical and health sciences0302 clinical medicinehistonesHumansMedicineEpigeneticsPrecision MedicineAged030304 developmental biologySubclinical infectionEpigenetic biomarkers0303 health sciencesDNA methylationFrailtybiologyexercisebusiness.industryStressorlcsh:RPublic Health Environmental and Occupational HealthPrecision medicineHistonehealthy agingDNA methylationbiology.proteinIdentification (biology)geriatric syndromesbusinessBiomarkers030217 neurology & neurosurgeryInternational Journal of Environmental Research and Public Health
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Social frailty increases the risk of all-cause mortality: A longitudinal analysis of the English Longitudinal Study of Ageing

2022

Objectives\ud Social frailty is a common condition in older people, but its consequences are largely unknown. Therefore, in this longitudinal analysis, we aimed to investigate the association between social frailty and risk of all-cause mortality in a large sample of older people.\ud Design\ud Longitudinal, cohort.\ud Settings and participants\ud Older people participating to the English Longitudinal Study of Ageing (ELSA).\ud Methods\ud Social frailty was defined based on financial difficulty, household status, social activity, and contacts with other people: social frailty was defined as ≥2 points, social pre-frailty (1 point), and robustness (0 points). Survival status during ten years o…

AgingFrailtyFrail ElderlyCell BiologyBiochemistryCohort StudiesEndocrinologyCohort ELSA Frailty Living alone Longitudinal Mortality Older people Poverty Social frailtyGeneticsHumansLongitudinal StudiesGeriatric AssessmentMolecular BiologyAgedProportional Hazards ModelsExperimental Gerontology
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