Search results for "Frail"
showing 10 items of 320 documents
The relationship between different settings of medical service and incident frailty
2018
Background: Some studies have reported a potential association between usual source of health care and disability, but no one has explored the association with frailty, a state of early and potential reversible disability. We therefore aimed to explore the association between older persons' self-reported usual source of health care at baseline and the onset of frailty. Methods: Information regarding usual source of health care was captured through self-report and categorized as 1) private doctor's office, 2) public clinic, 3) Health Maintenance Organization (HMO), or 4) hospital clinic/emergency department (ED). Frailty was defined using the Study of Osteoporotic Fracture (SOF) index as the…
Relation Between Genetic Factors and Frailty in Older Adults.
2018
Frailty is a geriatric syndrome that identifies individuals at higher risk of disability, institutionalization, and death. We previously reported that frailty is related to oxidative stress and cognitive impairment-related biomarkers. The aim of this study was to determine whether frailty is associated with genetic variants.Longitudinal population-based cohort of 2488 community-dwelling people from Toledo, Spain, aged 65 years or older.We obtained blood samples from 78 individuals with frailty and 74 nonfrail individuals who were nonfrail (according to Fried criteria) from the Toledo Study of Healthy Ageing and extracted DNA using the Chemagic DNA blood kit.Sample genotyping was carried out…
Estimation of the risk of the frailty syndrome in the independent-living population of older people.
2019
Frailty syndrome (FS) is one of the biggest problems faced by an ageing population. The aim of the study was to analyse selected parameters to assess the possibility of FS or symptoms related to this syndrome among independent and subjectively healthy people aged 60 + years and to select tests that may have a high level of diagnostic success while at the same time being easy to conduct, standardised and have a high level of reliability. The study group consisted of 1006 people aged 60 + years and the research protocol was very extensive, focusing on the broadly understood assessment of the functional biological markers of health in this group of people. The main outcome measures were hand-g…
Dimensions underlying frailty indicators in the Kihon Checklist.
2019
Aim Frailty has become a current topic of debate in recent years among researchers as a key concept of clinical care in old age. One of the scales developed for its measurement is the Kihon Checklist (KCL). However, the dimensionality of the KCL has not been tested yet, and therefore the aim of the present study was to validate its dimensional structure. Methods This was a cross-sectional study carried out between March and September 2018 in Valencia province (Spain). Participation in the study was voluntary. A total of 251 participants were sampled. They answered sociodemographic and medical indicators, as well as five frailty scales, including the KCL. Results Five confirmatory models wit…
Association between physical, psychological and social frailty and health-related quality of life among older people
2019
Abstract Background Studies on the association between frailty and health-related quality of life (HRQoL) are scarce and show contradictory results. This study aimed to evaluate the association between physical, psychological and social frailty and HRQoL among community-dwelling older people. Methods A cross-sectional study was performed with baseline data collected in 2015 from the Urban Health Centers Europe (UHCE) project in five European countries, the United Kingdom, Greece, Croatia, The Netherlands and Spain. A total of 2325 participants were included in the baseline measurements of the Urban Health Centers Europe project; 2167 participants (mean age = 79.7; SD=5.6) were included in t…
The effectiveness of a coordinated preventive care approach for healthy ageing (UHCE) among older persons in five European cities: A pre-post control…
2018
Abstract Background Older persons often have multiple health and social problems and need a variety of health services. A coordinated preventive approach that integrates the provision of health and social care services could promote healthy ageing. Such an approach can be organised differently, depending on the availability and organizational structures in the local context. Therefore, it is important to evaluate the effectiveness of a coordinated preventive care approach in various European settings. Objectives This study explored the effects of a coordinated preventive health and social care approach on the lifestyle, health and quality of life of community-dwelling older persons in five …
A home-based exercise program focused on proprioception to reduce falls in frail and pre-frail community-dwelling older adults.
2019
Frailty and falls are closely associated with each other as well as with disability, hospitalization, and death. Exercise can reduce these risks in both robust and frail older people. This before-after, non-randomized intervention study assessed a one-year proprioception training program with individual daily home exercises in 564 community-dwelling people aged 70 years and over, with different frailty phenotypes. After the exercise program, we observed a moderate reduction in the mean number of falls, fear of falls, body mass index and body fat percentage in frail and pre-frail participants. These results suggest that a home proprioception program may be a viable alternative to complex mul…
Frailty and Depression in Older Adults: A High-Risk Clinical Population
2014
Objective To identify salient characteristics of frailty that increase risk of death in depressed elders. Methods Data were from the Nordic Research on Ageing Study from research sites in Denmark, Sweden, and Finland. Participants were 1,027 adults aged 75 years (436 men and 591 women). Time of death was obtained, providing a maximum survival time of 11.08 years (initial evaluation took place between 1988 and 1991). Results Depressed elders showed greater baseline impairments in each frailty characteristic (gait speed, grip strength, physical activity levels, and fatigue). Simultaneous models including all four frailty characteristics showed slow gait speed (hazard ratio: 1.84; 95% confiden…
A coordinated preventive care approach for healthy ageing in five European cities: A mixed methods study of process evaluation components
2019
To evaluate specific process components of the Urban Health Centres Europe (UHCE) approach; a coordinated preventive care approach aimed at healthy ageing by decreasing falls, polypharmacy, loneliness and frailty among older persons in community settings of five cities in the United Kingdom, Greece, Croatia, the Netherlands and Spain.Mixed methods evaluation of specific process components of the UHCE approach: reach of the target population, dose of the intervention actually delivered and received by participants and satisfaction and experience of main stakeholders involved in the approach.The UHCE approach intervention consisted of a preventive assessment, shared decision-making on a care …
Multidimensional Frailty Predicts Mortality Better than Physical Frailty in Community-Dwelling Older People: A Five-Year Longitudinal Cohort Study
2021
Frailty is a common syndrome in older people that carries an increased risk of mortality. Two main models describe frailty, either as a loss of physical functions or as an accumulation of multiple deficits. The aim of our study was to compare the physical frailty index developed in the Cardiovascular Health Study (CHS) with a multidimensional frailty tool, the Multidimensional Prognostic Index (MPI), in predicting death in community-dwelling older subjects. Four hundred and seven community-dwelling older subjects were enrolled. Each subject underwent a comprehensive geriatric assessment (CGA) with calculation of the MPI and CHS index. Mortality was recorded over the following 5 years. In th…