Search results for "Frail"
showing 10 items of 320 documents
Assessing the Costs of Home Palliative Care in Italy: Results for a Demetra Multicentre Study
2022
Background: The sustainability of palliative care services is nowadays crucial inasmuch as resources for palliative care are internationally scarce, the funding environment is competitive, and the potential population is growing. Methods: The DEMETRA study is a multicentre prospective observational study, describing the intensity of care and the related costs of palliative home care pathways. Results: 475 patients were enrolled as recipients of specialized palliative home care. The majority of recipients were cancer patients (89.4%). The mean duration of palliative care pathways was 46.6 days and mean home care intensity coefficient equal to 0.6. The average daily cost of the model with the…
Understanding frailty:a qualitative study of European healthcare policy-makers' approaches to frailty screening and management
2018
ObjectiveTo elicit European healthcare policy-makers’ views, understanding and attitudes about the implementation of frailty screening and management strategies and responses to stakeholders’ views.DesignThematic analysis of semistructured qualitative interviews.SettingEuropean healthcare policy departments.ParticipantsSeven European healthcare policy-makers representing the European Union (n=2), UK (n=2), Italy (n=1), Spain (n=1) and Poland (n=1). Participants were sourced through professional networks and the European Commission Authentication Service website and were required to be in an active healthcare policy or decision-making role.ResultsSeven themes were identified. Our findings re…
Association Between Pollution and Frailty in Older People: A Cross-Sectional Analysis of the UK Biobank
2023
Objectives: Frailty is a relevant issue in older people, being associated with several negative outcomes. Increasing literature is reporting that pollution (particularly air pollution) can increase the risk of frailty, but the research is still limited. We aimed to investigate the potential association of pollution (air, noise) with frailty and prefrailty among participants 60 years and older of the UK Biobank study. Design: Cross-sectional. Settings and participants: Older participants (age ≥ 60 years) participating to the UK Biobank. Methods: Frailty and prefrailty presence were ascertained using a model including 5 indicators (weakness, slowness, weight loss, low physical activity, and e…
Frailty Tools for Assessment of Long-term Prognosis After Acute Coronary Syndrome
2020
Objective: To evaluate the 5 components of the Fried frailty phenotype (self-reported unintentional weight loss, physical activity questionnaire, gait speed, grip strength, and self-reported exhaustion) for long-term outcomes in elderly survivors of acute coronary syndrome. Methods: A total of 342 consecutive patients (from October 1, 2010, to February 1, 2012) were included. The 5 components of the Fried score and albumin concentration, as malnutrition index, were assessed before hospital discharge. Patients were followed up until April 2020 (median follow-up, 8.7 years). The end point was postdischarge all-cause mortality. Results: Mean ± SD age was 77±7 years and mean ± SD Fried score wa…
Sepsis at ICU admission does not decrease 30-day survival in very old patients : a post-hoc analysis of the VIP1 multinational cohort study
2020
AbstractBackgroundThe number of intensive care patients aged ≥ 80 years (Very old Intensive Care Patients; VIPs) is growing. VIPs have high mortality and morbidity and the benefits of ICU admission are frequently questioned. Sepsis incidence has risen in recent years and identification of outcomes is of considerable public importance. We aimed to determine whether VIPs admitted for sepsis had different outcomes than those admitted for other acute reasons and identify potential prognostic factors for 30-day survival.ResultsThis prospective study included VIPs with Sequential Organ Failure Assessment (SOFA) scores ≥ 2 acutely admitted to 307 ICUs in 21 European countries. Of 3869 acutely admi…
Corrigendum to “Inflammation and frailty in the elderly: A systematic review and meta-analysis” (Ageing Research Reviews (2016) 31 (1–18) (S156816371…
2017
Since the publication of our meta-analysis it has come to light that we inadvertently categorised one study (Gale et al. 2013) as a cross sectional study instead of its true design as a longitudinal study. We have recalculated the analyses affected which is isolated to the cross sectional longitudinal biomarkers of C reactive protein. The updated analyses have not significantly changed our findings regarding CRP or the narrative of the paper in any perceptible way. Specifically, the new OR for CRP longitudinal studies is now 1.08 (95%CI 0.87–1.34) compared to a previous value of 1.06 (95%CI: 0.78–1.44) (please see the new Fig. 1a). Similarly, after removing the study of Gale et al., the cro…
Pragmatic Diabetes Management in Nursing Homes: Individual Care Plan
2013
Although the management of diabetes as a simple entity has been extensively developed, there is a dearth of evidence in elderly, frail patients with multiple comorbidities and polymedication. This population represents a large proportion of the residents of nursing homes (NHs). As a multidisciplinary group of French experts (geriatricians, endocrinologists, diabetologists, and general practitioners) with practical experience in this area, which is growing in magnitude throughout the world, we convened to compile pragmatic, simple advice on the management of elderly, frail diabetic patients. Given demands on NH personnel (manager, medical coordinator, nurses, and, at the front line of care p…
Visiones y mentalidad arquitectónica de un maestro del siglo XVIII. "La Descripción breve de las medidas y magnificencia..." del Convento de Santa Cl…
2005
Presentamos el texto inédito de fray José Alberto Pina (1693-1772) titulado: "Descripcion breve de (...) el Real Monasterio de (...) Santa Clara", redactado a mediados del siglo XVIII, en el que describe pormenorizadamente este convento de la ciudad de Xátiva (Valencia), donde se manifiesta la formación técnica y constructiva de su autor, y una semblanza de su personalidad arquitectónica. (A)
Validation of the Clinical Frailty Scale for the Prediction of Mortality in Patients With Liver Cirrhosis
2020
Introduction Frailty is a common but often underestimated complication in patients with liver cirrhosis. The Clinical Frailty Scale (CFS) allows the assessment of frailty within a short period of time but has only been investigated in a Canadian cohort of outpatients. The aim of the current study was to evaluate the ability of the CFS to predict mortality in outpatients and nonelectively hospitalized German patients. Methods Two hundred outpatients and 99 nonelectively hospitalized patients with liver cirrhosis were prospectively enrolled. Outpatients/inpatients were followed for a median of 364/28 days regarding the primary outcome of death or liver transplantation. Eighty-seven patients o…
A linear regression-based machine learning pipeline for the discovery of clinically relevant correlates of gait speed reserve from multiple physiolog…
2021
Frailty in older adults is characterized by reduced physiological reserve. Gait speed reserve (GSR: maximum minus usual gait speed) could help identify frailty and act as a proxy for physiological reserve. Utilizing data from 2397 participants aged 50+ from wave 3 of The Irish Longitudinal Study on Ageing, we developed a stepwise linear regression-based machine learning pipeline to select the most important GSR predictors from 34 manually selected features across multiple domains. Variables were selected one at a time such that they maximized the mean adjusted r-squared score from a 5-fold cross-validation. A peak score of (0.16 +/- 0.03) was achieved with 14 variables (giving adjusted-r-sq…