Search results for "Frozen section procedure"

showing 10 items of 23 documents

RETRACTILE MESENTERITIS MIMICKING AN ADRENAL TUMOR

1999

Retractile mesenteritis is a nonspecific inflammatory process involving the adipose tissue of the mesentery.1 It is a diagnostic challenge to identify this benign condition and, thus, avoid unnecessary surgery. Although approximately 100 cases have been published describing stomach and intestine involvement,z to our knowledge involvement of the urological organs has not been described previously. Consequently the urological literature lacks any information on this pathological entity. We report a rare case of retractile mesenteritis presenting as an adrenal tumor. were obtained and sent for frozen section, which revealed fibrotic tissue similar to retroperitoneal fibrosis. Due to the extens…

Frozen section procedurePathologymedicine.medical_specialtybusiness.industryRetractile MesenteritisUrologyHistologyMalignancymedicine.diseaseRetroperitoneal fibrosismedicine.anatomical_structureMedicineDifferential diagnosismedicine.symptombusinessPancreasMesenteryThe Journal of Urology
researchProduct

Immuno-fluorescence cytochemistry on thin frozen sections of human substantia nigra for staining of monoamine oxidase A and monoamine oxidase B: a pi…

1990

Immunofluorescence cytochemistry on thin frozen sections of human substantia nigra for staining of MAO-A and MAO-B revealed that only about 10% of the melanin-containing neurons are positive for MAO-A, while they are substantially free of MAO-B.

Frozen section procedurebiologymedicine.diagnostic_testMonoamine oxidaseChemistrySubstantia nigraImmunofluorescenceMolecular biologyStainingnervous systemBiochemistrybiology.proteinmedicineCytochemistrysense organsMonoamine oxidase BMonoamine oxidase A
researchProduct

Splenogonadal Fusion: A Genetic Disorder?—Report of a Case and Review of the Literature

2014

Splenogonadal fusion is a rare congenital anomaly in which there is fusion between the spleen and gonad, epididymis or vas. We treated a patient with scrotal mass. A discontinuous fusion between the spleen and epididymis was found: after frozen section mass was excised sparing testis. Although rare, the splenogonadal fusion should be considered in the differential diagnosis of scrotal masses in children, and orchiectomy should be avoided. Moreover, examination of siblings showed a brother affected from accessory spleen. This finding, not reported previously to our knowledge, suggests a possible familiarity of this disorder. Keywords: Splenogonadal fusion, Testis, Accessory spleen

General Urologyendocrine systemPathologymedicine.medical_specialtyFrozen section procedureGonadurogenital systembusiness.industryUrologySpleenSplenogonadal fusionAccessory spleenlcsh:Diseases of the genitourinary system. Urologylcsh:RC870-923medicine.diseaseEpididymisAccessory spleenSplenogonadal fusionmedicine.anatomical_structureTestismedicineOrchiectomyDifferential diagnosisbusinessUrology Case Reports
researchProduct

Microsurgical testis-sparing surgery in small testicular masses: seven years retrospective management and results

2012

OBJECTIVE To retrospectively evaluate the clinical outcomes of 20 patients diagnosed with a nonpalpable or small testicular mass (2 cm) at 2 academic urological department. Testis-sparing surgery (TSS) is currently performed routinely for the management of nonpalpable testicular masses. High reliability of frozen section examination (FSE) and high-frequency ultrasound (US) and the adoption of microsurgical techniques improved safety and feasibility of this technique.METHODS From January 2004 to March 2011, 23 patients underwent microsurgical TSS. An inguinal approach was performed in 22 cases and a suprapubic incision in one bilateral case. All procedures were performed with an operating mi…

Germ-Cell TumorsMalemedicine.medical_specialtyMicrosurgeryUrologic Surgical Procedures MaleUrologyFollow-UpTestis sparing surgeryUrologic Surgical ProcedureTesticular NeoplasmsRetrospective StudieTestisUltrasoundHumansMedicineGerm-Cell Tumors; Organ Preservation; Preserving Surgery; Follow-Up; Ultrasound; Cancer; ResectionTesticular NeoplasmRetrospective StudiesCancerFrozen section procedurebusiness.industryUltrasoundTesticular massRetrospective cohort studyOrgan PreservationWarm ischemiaResectionSurgerySeminomaTreatment OutcomeTestiPreserving SurgerybusinessOperating microscopeMicrosurgical; testis-sparing; surgery; small testicular massesHuman
researchProduct

Comparative analysis of in situ versus ex situ perfusion on micro circulation in liver procurement--an experimental trial in a porcine model.

2012

The Achilles heel of liver transplantation remains the biliary system. The crucial step for liver preservation is effective rinsing and perfusion of the peribiliary plexus (PBP). Due to the physiology of the vascular tree, it seems almost impossible to achieve the necessary physiologic ranges of pressure and flow by the in situ perfusion technique. We investigated the role of additional ex situ perfusion via the hepatic artery in this animal model.Fifteen German Landrace pigs underwent standardized multiorgan procurement. In situ perfusion and additional ex situ perfusion were performed consecutively. Meanwhile the external pressure applied to the perfusion system was increased stepwise. To…

In situPathologymedicine.medical_specialtyTissue and Organ ProcurementSwinemedicine.medical_treatmentLiver transplantationMicrocirculationAnimal modelHepatic ArteryMedicineAnimalsLiver preservationTransplantationFrozen section procedurebusiness.industryMicrocirculationLiver TransplantationPerfusionmedicine.anatomical_structureModels AnimalSurgeryNuclear medicinebusinessPerfusionArteryTransplantation proceedings
researchProduct

Significance of the effective remnant liver volume in major hepatectomies

2005

The aim of this study is to identify the minimum safe amount of effective remnant liver volume (ERLV) in patients undergoing a major hepatectomy. Thirty-eight consecutive major hepatectomies (resection of ≥3 Couinaud segments) performed between July 1999 and March 2004 in which a frozen section liver biopsy was obtained were included. No patient had chronic viral hepatitis, cirrhosis, or cholestasis. The total liver volume (TLV) was calculated using the Vauthey formula, and the postsurgical liver volume (PSLV) was derived by subtracting the estimated volume of liver resected from the TLV. The PSLV minus the percentage of macrovesicular steatosis as nonfunctional liver was defined as the ef…

Malemedicine.medical_specialtyCirrhosisRisk AssessmentCohort StudiesPostoperative ComplicationsCholestasisLiver Function TestsmedicineHepatectomyHumansSurvival analysisProbabilityRetrospective StudiesCohort Studies; Female; Follow-Up Studies; Hepatectomy; Humans; Liver; Liver Function Tests; Liver Neoplasms; Male; Organ Size; Postoperative Complications; Probability; Retrospective Studies; Risk Assessment; Survival AnalysisFrozen section proceduremedicine.diagnostic_testbusiness.industryLiver NeoplasmsRetrospective cohort studyGeneral MedicineOrgan Sizemedicine.diseaseSurvival AnalysisSurgerySettore MED/18 - Chirurgia GeneraleLiverLiver biopsyFemaleLiver function testsbusinessViral hepatitisFollow-Up Studies
researchProduct

Targeted use of intraoperative frozen-section analysis lowers the frequency of completion thyroidectomy

2021

Abstract Background The impact of intraoperative frozen section (iFS) analysis on the frequency of completion thyroidectomy for the management of thyroid carcinoma is controversial. Although specialized endocrine centres have published their respective results, there are insufficient data from primary and secondary healthcare levels. The aim of this study was to analyse the utility of iFS analysis. Methods In the Prospective Evaluation Study Thyroid Surgery (PETS) 2 study, 22 011 operations for benign and malignant thyroid disease were registered prospectively in 68 European hospitals from 1 July 2010 to 31 December 2012. Group 1 consisted of 569 patients from University Medical Centre (UMC…

Malemedicine.medical_specialtymedicine.medical_treatmentMedizin030209 endocrinology & metabolismMalignancyThyroid carcinoma03 medical and health sciences0302 clinical medicineInternal medicinemedicineFrozen SectionsHumansProspective StudiesThyroid NeoplasmsThyroid NoduleCompletion thyroidectomyFrozen section procedureIntraoperative Carebusiness.industryThyroid diseaseThyroidectomyCancerGeneral Medicinemedicine.diseaseEuropeCross-Sectional Studies030220 oncology & carcinogenesisRelative riskThyroidectomyFemaleOriginal ArticleAcademicSubjects/MED00010business
researchProduct

Prognostic Impact of Frozen Section Investigation and Extent of Proximal Safety Margin in Gastric Cancer Resection

2020

Background and aims Guidelines propose different extents of macroscopic proximal margin for gastric cancer and frozen margin investigation in selected cases, but data is lacking. This study was to evaluate the necessary extent of macroscopic proximal margin, accuracy of frozen margin investigation, and prognostic impact of tumor-free proximal margin length in pT2-pT4 gastric cancer. Study design Proximal and distal frozen margins were routinely investigated intraoperatively in all pT2-pT4 gastric cancers resected between 2011 and 2017. Macroscopic and microscopic proximal margin lengths were correlated. For R0-resections, survival analysis was performed for distal gastrectomy (DG) with micr…

Malemedicine.medical_treatmentCancer resection03 medical and health sciences0302 clinical medicineGastrectomyStomach NeoplasmsMargin (machine learning)medicineFrozen SectionsHumansSurvival analysisAgedNeoplasm StagingFrozen section procedureCentimeterbusiness.industryMargins of ExcisionCancerHistologyMiddle AgedPrognosismedicine.diseaseSurvival Analysis030220 oncology & carcinogenesisFemale030211 gastroenterology & hepatologySurgeryGastrectomyNuclear medicinebusinessAnnals of Surgery
researchProduct

Intermediate filaments of normal and neoplastic tissues of the female genital tract with emphasis on problems of differential tumor diagnosis

1984

Cytokeratins of normal epithelia and of some neoplasms of the female genital tract were studied by immunofluorescence microscopy of frozen sections and by two-dimensional gel electrophoresis of cytoskeletal proteins from microdissected tissues. All normal epithelia were stained with the monoclonal cytokeratin antibody KG 8.13 whereas certain monoclonal antibodies stained only simple epithelia. As revealed by gel electrophoresis the normal epithelia of the ovarian surface, oviduct, endometrium and endocervix contained cytokeratin polypeptides Nos. 7, 8, 18 and 19. In contrast, stratified exocervical epithelium showed a much more complex pattern (polypeptides No. 1, 2, 4, 5, 6, 11, 13, 14, 15…

Pathologymedicine.medical_specialtyFrozen section procedureGenital Neoplasms Femalemedicine.drug_classFluorescent Antibody TechniqueCell BiologyBiologyEndometriumMonoclonal antibodyPathology and Forensic MedicineDiagnosis DifferentialCytokeratinmedicine.anatomical_structuremedicineGenital neoplasmHumansKeratinsImmunohistochemistryFemaleIntermediate filamentCytoskeletonEndocervixPathology - Research and Practice
researchProduct

MALDI MS imaging as a powerful tool for investigating synovial tissue

2012

To identify and image protein biomarker candidates in the synovial tissue of patients with rheumatoid arthritis (RA) and patients with osteoarthritis (OA).A novel matrix-assisted laser desorption/ionization (MALDI) imaging mass spectrometry (IMS) technique was applied to the analysis of synovial tissue. Patients were classified according to the American College of Rheumatology (ACR) criteria for RA. Frozen sections were stained to obtain morphological data. Serial sections were desiccated, and spotted with matrix for MALDI analysis. Ions generated by laser irradiation of the tissue were separated in time, based on their m/z ratio, and were subsequently detected. IMS was used in a 'profiling…

ProteomicsPathologymedicine.medical_specialtyImmunologyArthritisOsteoarthritisProteomicsMass spectrometryPeptide MappingArticleMass spectrometry imagingArthritis RheumatoidRheumatologyOsteoarthritismedicineHumansImmunology and AllergyFrozen section procedurebusiness.industrySynovial MembraneGeneral Medicinemedicine.diseaseMatrix-assisted laser desorption/ionizationmedicine.anatomical_structureSpectrometry Mass Matrix-Assisted Laser Desorption-IonizationSynovial membranebusinessBiomarkersScandinavian Journal of Rheumatology
researchProduct