Search results for "Function"
showing 10 items of 14432 documents
Glycaemic variability (measured by 48h continous glucose monitoring) in subjects with metabolic syndrome, with ot withoout diabetes,is indipendently …
2007
Postprandial hyperglycaemia induces endothelial dysfunction thus contributing to the appearance of atherosclerotic lesions and to the high cardiovascular risk of diabetic subjects. Subjects who develop diabetes have an increased cardiovascular risk even before the appearance of diabetes. Insulin resistant subjects with metabolic syndrome (MS) are at both high cardiovascular and diabetes risk and it cannot be excluded that higher postprandial glycaemic excursions might induce endothelial dysfunction in this condition. Furthermore, adipose tissue is known to release factors (adipokines) that are able to influence both insulin sensitivity and endothelial function. The glycaemic variability is …
Progettare interventi di sostegno didattico tra profilo di funzionamento e dimensioni di sviluppo
2023
Il contributo presenta le caratteristiche d’uso dell’International Classification of Functioning, Disability and Health (ICF, 2001) per strutturare a scuola percorsi differenziati per gli alunni in situazione di disabilità. L’insegnante ha il compito di creare un ambiente di apprendimento inclusivo, di organizzare attività coerenti con gli obiettivi, di usare strategie adeguate ai bisogni educativi. Per progettare interventi efficaci di sostegno didattico egli osserva le difficoltà e le capacità potenziali dell’alunno, si propone lo sviluppo e il miglioramento di performance significative nel contesto, pensa come insegnare per favorire la partecipazione, personalizza le verifiche e valuta c…
Inter- and Intraobserver Variation in the Assessment of Preoperative Colostograms in Male Anorectal Malformations: An ARM-Net Consortium Survey
2020
Aim:Male patients with anorectal malformations (ARM) are classified according to presence and level of the recto-urinary fistula. This is traditionally established by a preoperative high-pressure distal colostogram that may be variably interpreted by different surgeons. The aim of this study was to evaluate the inter- and intraobserver variation in the assessment by pediatric surgeons of preoperative colostograms with respect to the level of the recto-urinary fistula. Materials and Methods:Sixteen pediatric surgeons from 14 European centers belonging to the ARM-Net Consortium twice scored 130 images of distal colostograms taken in sagittal projection at a median age of 66 days of life (rang…
B‐DNA structure and stability: the role of nucleotide composition and order
2022
Abstract We have quantum chemically analyzed the influence of nucleotide composition and sequence (that is, order) on the stability of double‐stranded B‐DNA triplets in aqueous solution. To this end, we have investigated the structure and bonding of all 32 possible DNA duplexes with Watson–Crick base pairing, using dispersion‐corrected DFT at the BLYP‐D3(BJ)/TZ2P level and COSMO for simulating aqueous solvation. We find enhanced stabilities for duplexes possessing a higher GC base pair content. Our activation strain analyses unexpectedly identify the loss of stacking interactions within individual strands as a destabilizing factor in the duplex formation, in addition to the better‐known eff…
Estudio de funciones con geogebra
2012
Nuestra investigación, “Estudio de funciones con GeoGebra”, se ha desarrollado en el “Máster Universitario en Profesor de Educación Secundaria” de la Universitat de València. El estudio se centra en cómo alcanzar una correcta comprensión de los conceptos referidos a funciones haciendo uso del GeoGebra. El problema que motiva esta investigación radica en que, en los cursos tradicionales de 2º de Bachillerato, cantidades significativas de estudiantes no logran comprender los conceptos básicos de funciones, en particular, la tasa de variación media, derivada, monotonía, extremos y concavidad. El proyecto tiene como objetivo hacer una propuesta de trabajo basada en la utilización de GeoGebra, d…
Testing the Sobolev property with a single test plan
2020
We prove that in a vast class of metric measure spaces (namely, those whose associated Sobolev space is separable) the following property holds: a single test plan can be used to recover the minimal weak upper gradient of any Sobolev function. This means that, in order to identify which are the exceptional curves in the weak upper gradient inequality, it suffices to consider the negligible sets of a suitable Borel measure on curves, rather than the ones of the $p$-modulus. Moreover, on $\sf RCD$ spaces we can improve our result, showing that the test plan can be also chosen to be concentrated on an equi-Lipschitz family of curves.
Monotonicity Formulas for Harmonic Functions in RCD(0,N) Spaces
2023
We generalize to the RCD(0,N) setting a family of monotonicity formulas by Colding and Minicozzi for positive harmonic functions in Riemannian manifolds with nonnegative Ricci curvature. Rigidity and almost rigidity statements are also proven, the second appearing to be new even in the smooth setting. Motivated by the recent work in Agostiniani et al. (Invent. Math. 222(3):1033–1101, 2020), we also introduce the notion of electrostatic potential in RCD spaces, which also satisfies our monotonicity formulas. Our arguments are mainly based on new estimates for harmonic functions in RCD(K,N) spaces and on a new functional version of the ‘(almost) outer volume cone implies (almost) outer metric…
The historical role played by the work of Ulisse Dini on implicit function theory in the modern differential geometry foundations: the case of the st…
2012
On Variational Measures Related to Some Bases
2000
Abstract We extend, to a certain class of differentiation bases, some results on the variational measure and the δ-variation obtained earlier for the full interval basis. In particular the theorem stating that the variational measure generated by an interval function is σ-finite whenever it is absolutely continuous with respect to the Lebesgue measure is extended to any Busemann–Feller basis.
Recent Advances on the Halo- and Cyano-Trifluoromethylation of Alkenes and Alkynes
2021
Incorporation of fluorine into organic molecules is a well-established strategy in the design of advanced materials, agrochemicals, and pharmaceuticals. Among numerous modern synthetic approaches, functionalization of unsaturated bonds with simultaneous addition of trifluoromethyl group along with other substituents is currently one of the most attractive methods undergoing wide-ranging development. In this review article, we discuss the most significant contributions made in this area during the last decade (2012−2021). The reactions reviewed in this work include chloro-, bromo-, iodo-, fluoro- and cyano-trifluoromethylation of alkenes and alkynes.