Search results for "Furan"

showing 10 items of 667 documents

CCDC 922164: Experimental Crystal Structure Determination

2022

Related Article: Liāna Orola, Anatoly Mishnev, Dmitrijs Stepanovs, Agris Bērziņš|2022|ChemRxiv|||doi:10.26434/chemrxiv-2022-rb0xk

1-{[3-(5-nitrofuran-2-yl)prop-2-en-1-ylidene]amino}imidazolidine-24-dione dimethyl sulfoxide solvateSpace GroupCrystallographyCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
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CCDC 1421617: Experimental Crystal Structure Determination

2016

Related Article: Jakob Wudarczyk, George Papamokos, Vasilis Margaritis, Dieter Schollmeyer, Felix Hinkel, Martin Baumgarten, George Floudas, Klaus Müllen|2016|Angew.Chem.,Int.Ed.|55|3220|doi:10.1002/anie.201508249

22-Dimethyl-23-dihydro-1H-benzimidazole-4567-tetracarbonitrile tetrahydrofuran solvateSpace GroupCrystallographyCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
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CCDC 838880: Experimental Crystal Structure Determination

2012

Related Article: J.Barjau, J.Fleischhauer, G.Schnakenburg, S.R.Waldvogel|2011|Chem.-Eur.J.|17|14785|doi:10.1002/chem.201102722

2467a911-Hexamethyl-12b-((1-phenylpropyl)amino)-12a12b-dihydrobenzo[b][1]benzofuro[23-e][1]benzofuran-5a(7aH)-olSpace GroupCrystallographyCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
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CCDC 1474771: Experimental Crystal Structure Determination

2016

Related Article: Uğur Kaya, Pankaj Chauhan, Kristina Deckers, Rakesh Puttreddy, Kari Rissanen, Gerhard Raabe, Dieter Enders|2016|Synthesis|48|3207|doi:10.1055/s-0035-1561468

2-benzylidene-3-(nitromethyl)-3567-tetrahydro-1-benzofuran-4(2H)-oneSpace GroupCrystallographyCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
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SYNTHESIS AND ANTITUMOR ACTIVITY OF 2,5-BIS(3'-INDOLYL)-FURANS AND 3,5-BIS(3'-INDOLIY)-ISOXAZOLES, NORTOPSENTIN ANALOGUES

2010

Abstract A series of novel 2,5-bis(3′-indolyl)furans and 3,5-bis(3′-indolyl)isoxazoles were synthesized as antitumor agents. The antiproliferative activity was evaluated in vitro toward diverse human tumor cell lines. Initially 5 isoxazoles and 3 furan derivatives were tested against a panel of 10 human tumor cell lines and the most active derivatives 3c and 4a were selected to be evaluated in an extended panel of 29 cell lines. By exhibiting mean IC50 values of 17.4 μg/mL (3a) and 20.5 μg/mL (4c), in particular 4c showed a high level of tumor selectivity toward the 29 cell lines.

35-BIS(3'-INDOLIY)-ISOXAZOLESIndolesStereochemistry3Clinical Biochemistry2Pharmaceutical ScienceAntineoplastic AgentsBiochemistryChemical synthesis25-BIS(3'-INDOLYL)-FURANSchemistry.chemical_compound2; 5-BIS(3'-INDOLYL)-FURANS; 3; 5-BIS(3'-INDOLIY)-ISOXAZOLES; NORTOPSENTIN; ANTITUMOR ACTIVITYFuranCell Line TumorNeoplasmsDrug DiscoveryHumans5-BIS(3'-INDOLIY)-ISOXAZOLESCytotoxicityFurans5-BIS(3'-INDOLYL)-FURANSMolecular BiologyAntitumor activityAlkaloidOrganic ChemistryBiological activityNORTOPSENTINIsoxazolesSettore CHIM/08 - Chimica FarmaceuticaIn vitroANTITUMOR ACTIVITYchemistryCell cultureMolecular MedicineDrug Screening Assays Antitumor
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CCDC 891057: Experimental Crystal Structure Determination

2012

Related Article: G.Bentabed-Ababsa, S.Hamza-Reguig, A.Derdour, L.R.Domingo, J.A.Saez, T.Roisnel, V.Dorcet, E.Nassar, F.Mongin|2012|Org.Biomol.Chem.|10|8434|doi:10.1039/c2ob26442k

35-Diphenylfuran-22(5H)-dicarbonitrileSpace GroupCrystallographyCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
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CCDC 2077766: Experimental Crystal Structure Determination

2022

Related Article: Aija Trimdale, Anatoly Mishnev, Agris Bērziņš|2021|Pharmaceutics|13|734|doi:10.3390/pharmaceutics13050734

35-dihydroxybenzoic acid tetrahydrofuran solvateSpace GroupCrystallographyCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
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CCDC 1862873: Experimental Crystal Structure Determination

2018

Related Article: A. Zagidullin, D. Islamov, E. Oshchepkova, P. Lonnecke, V. Miluykov|2018|Acta Crystallogr.,Sect.E:Cryst.Commun.|74|1336|doi:10.1107/S2056989018011775

3-(triphenylphosphoranylidene)-25-dihydrofuran-25-dione tetrahydrofuran solvateSpace GroupCrystallographyCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
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CCDC 1816139: Experimental Crystal Structure Determination

2018

Related Article: Aysun Çapcı Karagöz, Christoph Reiter, Ean-Jeong Seo, Lisa Gruber, Friedrich Hahn, Maria Leidenberger, Volker Klein, Frank Hampel, Oliver Friedrich, Manfred Marschall, Barbara Kappes, Thomas Efferth, Svetlana B. Tsogoeva|2018|Bioorg.Med.Chem.|26|3610|doi:10.1016/j.bmc.2018.05.041

3-[2-(2H-13-benzodioxol-5-yl)-7-methoxy-1-benzofuran-5-yl]propan-1-olSpace GroupCrystallographyCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
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Sensitivity of 3He NMR parameters to the proximity of heterocyclic rings. The helium–furan dimer

2014

The potential of NMR technique in probing the interaction between a noble gas atom (used as a spectroscopic probe) and five-membered heterocyclic systems was theoretically studied. Selected 3He NMR parameters of free noble gas atom and its dimer were calculated using density functional theory with three functionals (M06-2X, CAM-B3LYP, and APFD), combined with dedicated polarization-consistent basis sets, and critically compared with theoretical high level calculations from the literature. The change of sotropic nuclear magnetic shielding of free noble gas atom in the presence of furan (3He placed above he middle of the ring and used as NMR probe) increased with its proximity to the heterocy…

3He NMRmolecular modelingfuranChemistry of Heterocyclic Compounds
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