Search results for "Fuzziness"
showing 10 items of 30 documents
Subtracting the sequence bias from partially digested MNase-seq data reveals a general contribution of TFIIS to nucleosome positioning.
2017
Background TFIIS stimulates RNA cleavage by RNA polymerase II and promotes the resolution of backtracking events. TFIIS acts in the chromatin context, but its contribution to the chromatin landscape has not yet been investigated. Co-transcriptional chromatin alterations include subtle changes in nucleosome positioning, like those expected to be elicited by TFIIS, which are elusive to detect. The most popular method to map nucleosomes involves intensive chromatin digestion by micrococcal nuclease (MNase). Maps based on these exhaustively digested samples miss any MNase-sensitive nucleosomes caused by transcription. In contrast, partial digestion approaches preserve such nucleosomes, but intr…
A very brief history of soft computing: Fuzzy Sets, artificial Neural Networks and Evolutionary Computation
2013
This paper gives a brief presentation of history of Soft Computing considered as a mix of three scientific disciplines that arose in the mid of the 20th century: Fuzzy Sets and Systems, Neural Networks, and Evolutionary Computation. The paper shows the genesis and the historical development of the three disciplines and also their meeting in a coalition in the 1990s.
Fuzziness, Cognition and Cybernetics: an outlook on future
2015
In the present paper, we connect some old reflections about the relationships existing between the theory of fuzzy sets and cybernetics with modern, contemporary analyses of the crucial (better: unavoidable) role that fuzziness plays in the attempts at scientifically describing aspects of information sciences. The connection, which has a basic conceptual origin, has been triggered also by the recent 50th anniversary of Norbert Wiener’ death which has been instrumental in looking again at some crucial aspects of the birth of information sciences in the midst of last Century. Fuzzy sets are an essential part of this revolution and share all the innovations as well as the difficulties of this …
Varieties of Vagueness, Fuzziness and a few foundational (and ontological) questions
2011
In this paper we discuss the multifaceted nature of vagueness, the limits of (standard) set theory in dealing with the foundational aspects that a really innovating theory of vagueness should manifest, and the difficul- ties in outlining the possible features that such a type of new formalism should exhibit in order to be able to deal with such innovative aspects. We shall highlight some aspects of the role that Fuzzy Set Theory (FST) can play in this process.
FUZZINESS: the emergence of a new scientific concept
2011
Kazem Sadegh-Zadeh's lifework on philosophy of medicine
2013
Fuzziness in Italy – Traces of a scattered history
2017
The history of Fuzziness in Italy is varied and scattered among a num- ber of research groups. As a matter of fact, “fuzziness” spread in Italy through a sort of spontaneous diffusion, and, also subsequently, no one felt the need to cre- ate some “national” common structure like an Association or similar things. Since a cohesive retelling would be next to impossible, a few members of the Italian fuzzy community have been asked to recount their experience and express their hopes for the future.
Specificities and Vagaries of Medicine from the Viewpoint of Hard Sciences
2013
Among many other beautiful reflections on the ontology of medicine, in his Handbook of Analytic Philosophy of Medicine, Sadegh Zadeh promotes Fuzzy Sets Theory among the basic instruments of logic for medical understanding, highlights the importance of vagueness in the medical language and as an intrinsic property of medical epistemology, and invokes the clear advantages of a medical fuzzy taxonomy to overcome the binary concept of being healthy/ill. We briefly discuss these aspects, relating them to the peculiarity of Fuzziness as the only purely scientific notion among the foundational tools needed to define an analytic philosophy of medicine more concerned with an explicatum of the notio…