Search results for "G13"

"Figure 11" of "Cold-nuclear-matter effcts on heavy-quark production in d+Au collisions at sqrt(s_NN)=200 GeV"

2023

Heavy flavor electron $R_{dA}$ 60-88% $d$+Au collisions. The nuclear modification factor, $R_{dA}$, for electrons from open heavy flavor decays, for the (a) most central and (b) most peripheral centrality bins.

"Figure 8" of "Cold-nuclear-matter effcts on heavy-quark production in d+Au collisions at sqrt(s_NN)=200 GeV"

2023

Heavy flavor electron RdA 0-20% $d$+Au collisions. The nuclear modification factor, $R_{dA}$, for electrons from open heavy flavor decays, for the (a) most central and (b) most peripheral centrality bins.

"Figure 9" of "Cold-nuclear-matter effcts on heavy-quark production in d+Au collisions at sqrt(s_NN)=200 GeV"

2023

Heavy flavor electron $R_{dA}$ 20-40% $d$+Au collisions. The nuclear modification factor, $R_{dA}$, for electrons from open heavy flavor decays, for the (a) most central and (b) most peripheral centrality bins.

"Figure 7" of "Cold-nuclear-matter effcts on heavy-quark production in d+Au collisions at sqrt(s_NN)=200 GeV"

2023

Heavy flavor electron $R_{dA}$ 0-100% d+Au collisions. The nuclear modification factors $R_{dA}$ and $R_{AA}$ for minimum bias $d$+Au and Au+Au collisions, for the $\pi^{0}$ and $e^{\pm}_{HF}$. The two boxes on the right side of the plot represent the global uncertainties in the $d$+Au (left) and Au+Au (right) values of $N_{coll}$ . An additional common global scaling uncertainty of 9.7% on $R_{dA}$ and $R_{AA}$ from the $p+p$ reference data is omitted for clarity.

"Figures 3-6" of "Cold-nuclear-matter effcts on heavy-quark production in d+Au collisions at sqrt(s_NN)=200 GeV"

2023

Heavy flavor electron yield, $d$+Au $\implies$ CHARGED X. Electrons from heavy flavor decays, separated by centrality. The lines represent a fit to the previous $p+p$ result [23], scaled by $N_{coll}$. The inset shows the ratio of photonic background electrons determined by the converter and cocktail methods for Minimum Bias $d$+Au collisions, with error bars (boxes) that represent the statistical uncertainty on the converter data (systematic uncertainty on the photonic-electron cocktail).

"Figure 10" of "Cold-nuclear-matter effcts on heavy-quark production in d+Au collisions at sqrt(s_NN)=200 GeV"

2023

Heavy flavor electron $R_{dA}$ 40-60% $d$+Au collisions. The nuclear modification factor, $R_{dA}$, for electrons from open heavy flavor decays, for the (a) most central and (b) most peripheral centrality bins.

"Figures 1-2" of "Cold-nuclear-matter effcts on heavy-quark production in d+Au collisions at sqrt(s_NN)=200 GeV"

2023

Heavy flavor electron yield, Run-8 $p$ + $p$, $d$+Au collisions. Electrons from heavy flavor decays, separated by centrality. The lines represent a fit to the previous $p+p$ result [23], scaled by $N_{coll}$. The inset shows the ratio of photonic background electrons determined by the converter and cocktail methods for Minimum Bias $d$+Au collisions, with error bars (boxes) that represent the statistical uncertainty on the converter data (systematic uncertainty on the photonic-electron cocktail).

The receptor protein tyrosine phosphatase PTPRJ negatively modulates the CD98hc oncoprotein in lung cancer cells.

2018

PTPRJ, a receptor protein tyrosine phosphatase strongly downregulated in human cancer, displays tumor suppressor activity by negatively modulating several proteins involved in proliferating signals. Here, through a proteomic-based approach, we identified a list of potential PTPRJ-interacting proteins and among them we focused on CD98hc, a type II glycosylated integral membrane protein encoded by SLC3A2, corresponding to the heavy chain of a heterodimeric transmembrane amino-acid transporter, including LAT1. CD98hc is widely overexpressed in several types of cancers and contributes to the process of tumorigenesis by interfering with cell proliferation, adhesion, and migration. We first valid…

NF-κB Is a Potential Molecular Drug Target in Triple-Negative Breast Cancers.

2017

Breast cancer continues to cause significant burden in global health morbidity and mortality. Triple-negative breast cancers (TNBCs) are highly aggressive with poor prognosis and are characterized by lack of expression of estrogen receptor, progesterone receptor, and human epidermal growth factor receptor (Her-2). TNBCs are often resistant to cytotoxic chemotherapy and pose major difficulty in achieving personalized medicine due to their molecular heterogeneity. There is increasing evidence that the aberrant activation of nuclear factor (NF)-κB signaling is a frequent characteristic of TNBCs. We evaluated the effects of different potential NF-κB inhibitors, such as bisindolylmaleimide I (BI…

2019

Traumatic brain injury (TBI) can lead to impaired cognition and memory consolidation. The acute phase (24–48 h) after TBI is often characterized by neural dysfunction in the vicinity of the lesion, but also in remote areas like the contralateral hemisphere. Protein homeostasis is crucial for synaptic long-term plasticity including the protein degradation systems, proteasome and autophagy. Still, little is known about the acute effects of TBI on synaptic long-term plasticity and protein degradation. Thus, we investigated TBI in a controlled cortical impact (CCI) model in the motor and somatosensory cortex of mice ex vivo-in vitro. Late long-term potentiation (l-LTP) was induced by theta-burs…