Search results for "G8"
showing 3 items of 23 documents
Il codice Pontecorvo
2016
Gli ultimi lavori di Pontecorvo, dopo il congedo dal cinema pensato per il grande schermo avvenuto con Ogro. Una serie di documentari, perlopiù regie collettive dal taglio politico e militante, con l’eccezione del cortometraggio Nostalgia di protezione. Il successo di Un altro mondo è possibile, il film sul G8 di Genova del 2001. L’addio definitivo, e il simbolico passaggio del testimone con suo figlio Marco. Esiste un “lascito” cinematografico del regista? L’influenza sul cinema americano contemporaneo, dalla New Hollywood in poi, e qualche equivoco. Alcuni possibili “eredi”, in Italia e all’estero.
Prognostic value of two geriatric screening tools in a cohort of older patients with early stage Non-Small Cell Lung Cancer treated with hypofraction…
2020
Objectives: To investigatewhether assessmentwith two geriatric screening tools shows a correlationwith clinical outcomes of patients aged 65 years or more, with early-stage Non-Small Cell Lung Cancer (es-NSCLC) treated with hypofractionated stereotactic radiotherapy. Methods: FromMarch 2014 to June 2018we retrospectively evaluated 42 patientswith stage I and II lung tumors. Patients were assessed with Charlson Comorbidity Index (CCI) and G8 screening tool. Median age was 74 years (range, 65–91). Stereotactic radiotherapy was performed with Helical Tomotherapy delivering 50–70 Gray (Gy) in 8–10 fractions. Toxicity was evaluated using Common Terminology Criteria for Adverse Events v4.0 criter…
Rab33B and its autophagic Atg5/12/16L1 effector assist in hepatitis B virus naked capsid formation and release
2015
Hepatitis B virus morphogenesis is accompanied by the production and release of non-enveloped capsids/nucleocapsids. Capsid particles are formed inside the cell cytosol by multimerization of core protein subunits and ultimately exported in an uncommon coatless state. Here, we investigated potential roles of Rab GTPases in capsid formation and trafficking by using RNA interference and overexpression studies. Naked capsid release does not require functions of the endosome-associated Rab5, Rab7 and Rab27 proteins, but depends on functional Rab33B, a GTPase participating in autophagosome formation via interaction with the Atg5-Atg12/Atg16L1 complex. During capsid formation, Rab33B acts in conju…