Search results for "GC"
showing 10 items of 606 documents
Expression profiling of glial genes during Drosophila embryogenesis
2006
AbstractIn the central nervous system of Drosophila, the induction of the glial cell fate is dependent on the transcription factor glial cells missing (gcm). Though a considerable number of other genes have been shown to be expressed in all or in subsets of glial cells, the course of glial cell differentiation and subtype specification is only poorly understood. This prompted us to design a whole genome microarray approach comparing gcm gain-of-function and, for the first time, gcm loss-of-function genetics to wildtype in time course experiments along embryogenesis. The microarray data were analyzed with special emphasis on the temporal profile of differential regulation. A comparison of bo…
Assessment of polycyclic aromatic hydrocarbons (PAHs) in soil of a Natural Reserve (Isola delle Femmine) (Italy) located in front of a plant for the …
2009
Isola delle Femmine Natural Reserve is a very little isle about 15 km from the centre of Palermo, in front of a plant for the production of cement and about 600 m from coast. In the present research, profiles soil PAHs were obtained for 16 sites within the reserve and for 8 stations on the rural soil taken as reference. summation Sigma PAHs, in the soil of investigated area, ranged from 35 to 545 microg/kg. With the aim to find the origin of PAHs in the soil of Isola delle Femmine, we compare the distribution of single analytes in the investigated area with those of the reference rural area (Monte Raffo Rosso), with those of atmospheric urban particulate collected at Palermo along with repo…
From Buildings' End of Life to Aggregate Recycling under a Circular Economic Perspective: A Comparative Life Cycle Assessment Case Study
2021
The demolition of buildings, apart from being energy intensive and disruptive, inevitably produces construction and demolition waste (C&Dw). Unfortunately, even today, the majority of this waste ends up underexploited and not considered as valuable resources to be re-circulated into a closed/open loop process under the umbrella of circular economy (CE). Considering the amount of virgin aggregates needed in civil engineering applications, C&Dw can act as sustainable catalyst towards the preservation of natural resources and the shift towards a CE. This study completes current research by presenting a life cycle inventory compilation and life cycle assessment case study of two buildin…
Age-dependent regulation of antioxidant genes by p38α MAPK in the liver
2018
p38α is a redox sensitive MAPK activated by pro-inflammatory cytokines and environmental, genotoxic and endoplasmic reticulum stresses. The aim of this work was to assess whether p38α controls the antioxidant defense in the liver, and if so, to elucidate the mechanism(s) involved and the age-related changes. For this purpose, we used liver-specific p38α-deficient mice at two different ages: young-mice (4 months-old) and old-mice (24 months-old). The liver of young p38α knock-out mice exhibited a decrease in GSH levels and an increase in GSSG/GSH ratio and malondialdehyde levels. However, old mice deficient in p38α had higher hepatic GSH levels and lower GSSG/GSH ratio than young p38α knock-…
Jet collimation in NGC 315 and other nearby AGN
2020
Aims. The collimation of relativistic jets in galaxies is a poorly understood process. Detailed radio studies of the jet collimation region have been performed so far in few individual objects, providing important constraints for jet formation models. However, the extent of the collimation zone as well as the nature of the external medium possibly confining the jet are still debated. Methods. In this article we present a multi-frequency and multi-scale analysis of the radio galaxy NGC 315, including the use of mm-VLBI data up to 86 GHz, aimed at revealing the evolution of the jet collimation profile. We then consider results from the literature to compare the jet expansion profile in a samp…
Nanoparticles and their influence on radionuclide mobility in deep geological formations
2012
International audience; This article gives an overview of the current status of knowledge concerning the role of nanoparticles (inorganic and organic) in deep geological host rocks and the potential influence of these nanoparticles on radionuclide migration in far-field systems. The manuscript is not intended to be a full review paper or overview paper concerning nanoparticles, here the intention is to refer to recent publications but to highlight the progress made in the 6th framework project IP FUNMIG (Fundamental processes of radionuclide migration) and the open literature over the past 5 a concerning the process understanding of nanoparticle related issues in the three host rock formati…
Zirconium–hafnium and rare earth element signatures discriminating the effect of atmospheric fallout from hydrothermal input in volcanic lake water
2016
The geochemical behaviour of Rare Earth Elements, Zr and Hf was investigated in the thermal waters of Nevado del Ruiz volcano system. A wide range of pH, between 1.0 and 8.8, characterizes these fluids. The acidicwaters are sulphate dominatedwith different Cl/SO4 ratios. The important role of the pH and the ionic complexes for the distribution of REE, Zr a nd Hf in the aqueous phase was evidenced. The pH rules the precipitation of authigenic Fe and Al oxyhydroxides producing changes in REE, Zr, Hf amounts and strong anomalies of Cerium. The precipitation of alunite and jarosite removes LREE from the solution, changing the REE distribution in acidic waters. Y-Ho and Zr-Hf (twin pairs) have a…
Investigation of modern oil paints through a physico-chemical integrated approach. Emblematic cases from Valencia, Spain
2020
Abstract The study and the characterisation of modern and contemporary oil paintings is still a challenging issue, in particular considering the significant changes in paint production across the 19th and 20th centuries. This paper presents the results of the first physico-chemical integrated study of the artistic materials used in six paintings from the School of Art and Higher Design of Valencia (Escola d'Art i Superior de Disseny, EASD-Valencia), artworks created between 1871 and 1943 by four famous Valencian artists: Salustiano Asenso Arozarena, Salvador Abril I Blasco, Enrique Navas Escuriet and Jose Bellver Delmas. A wide range of inorganic and organic compounds was identified through…
p27Kip1participates in the regulation of endoreplication in differentiating chick retinal ganglion cells
2015
Nuclear DNA duplication in the absence of cell division (i.e. endoreplication) leads to somatic polyploidy in eukaryotic cells. In contrast to some invertebrate neurons, whose nuclei may contain up to 200,000-fold the normal haploid DNA amount (C), polyploid neurons in higher vertebrates show only 4C DNA content. To explore the mechanism that prevents extra rounds of DNA synthesis in these latter cells we focused on the chick retina, where a population of tetraploid retinal ganglion cells (RGCs) has been described. We show that differentiating chick RGCs that express the neurotrophic receptors p75 and TrkB while lacking retinoblastoma protein, a feature of tetraploid RGCs, also express p27K…
Frequency-Sliding Generalized Cross-Correlation: A Sub-Band Time Delay Estimation Approach
2020
The generalized cross correlation (GCC) is regarded as the most popular approach for estimating the time difference of arrival (TDOA) between the signals received at two sensors. Time delay estimates are obtained by maximizing the GCC output, where the direct-path delay is usually observed as a prominent peak. Moreover, GCCs play also an important role in steered response power (SRP) localization algorithms, where the SRP functional can be written as an accumulation of the GCCs computed from multiple sensor pairs. Unfortunately, the accuracy of TDOA estimates is affected by multiple factors, including noise, reverberation and signal bandwidth. In this paper, a sub-band approach for time del…