Search results for "GDO."
showing 10 items of 382 documents
Brytyjska polityka europejska jako wyzwanie dezintegracyjne
2018
This article analyses the Brexit problem in the light of main concepts of differentiated integration. Great Britain, enjoying the status of preferential membership in the European union, benefited from the positive discrimination in many sectoral policies. After 23 June 2016 Brexit referendum, David Cameron’s and Theresa May’s governments work towards the status of preferential non-membership, opening a new chapter in the debate about differentiated forms of integration in Europe.
Longitudinal heritability of childhood aggression
2016
The genetic and environmental contributions to the variation and longitudinal stability in childhood aggressive behavior were assessed in two large twin cohorts, the Netherlands Twin Register (NTR), and the Twins Early Development Study (TEDS; United Kingdom). In NTR, maternal ratings on aggression from the Child Behavior Checklist (CBCL) were available for 10,765 twin pairs at age 7, for 8,557 twin pairs at age 9/10, and for 7,176 twin pairs at age 12. In TEDS, parental ratings of conduct disorder from the Strength and Difficulty Questionnaire (SDQ) were available for 6,897 twin pairs at age 7, for 3,028 twin pairs at age 9 and for 5,716 twin pairs at age 12. In both studies, stability and…
Repubblica e umanesimo in Italia nel XV secolo. Una introduzione
2022
The article introduces the three essays that make up the monographic section of this issue, Republic and Humanism in Italy in the Fifteenth Century. They examine, in an innovative way, the problem of the relationship between humanism and political cultures in three different contexts: the towns of the Veneto, the communities of Friuli (all under Venetian rule: the former studied by Clémence Revest, the latter by Lorenzo Freschi), the Kingdom of Naples and, in particular, its great capital (Monica Santangelo). Despite the obvious peculiarities of each of these realities, these contributions share an attempt to rethink the Italian political space and the categories with which it has long been…
Los Requena, una enigmática familia de pintores del Renacimiento. A propósito de Gaspar Requena <i>el Joven</i>
2009
Recent exhibitions produced by the Foundation <i>La Luz de las Imágenes</i> in Valencian dioceses has allowed for numerous works of art to be seen, admired and studied under optimal conditions. In this context we offer an approach to the workshop of the Requena family, painters active in the Kingdom of Valencia between approximately 1531 and 1605. These artists, in their uneven production, owed much to Paolo da San Leocadio, the Hernandos and particularly, Joan de Joanes.<br><br>Las recientes exposiciones que viene realizando la Fundación “La Luz de las Imágenes” en el ámbito de las distintas diócesis valencianas no sólo ha acercado al público numerosas obras de arte…
Mothers’ non-standard working and childcare-related challenges : A comparison between lone and coupled mothers
2016
Purpose – The purpose of this paper is to particularly focus on lone-mother families, comparing the childcare-related challenges experienced by working lone mothers and coupled mothers in three European countries in the context of a 24/7 economy and non-standard working hours (e.g. evening, night and weekend work). Design/methodology/approach – This study utilises survey data from Finnish, Dutch and British working mothers (n=1,106) collected as part of the “Families 24/7” research project. Multivariate regression analysis is used to analyse the associations between childcare-related challenges, maternal non-standard working, lone motherhood and country of residence. Findings – The results…
Underestimation of cognitive impairments by the Montreal Cognitive Assessment (MoCA) in an acute stroke unit population
2013
Abstract Background and purpose The Montreal Cognitive Assessment (MoCA) is an increasingly popular clinical screening tool for detecting cognitive impairment in stroke, but few studies have directly compared performance on the MoCA with neuropsychological assessment. Our retrospective study examined the extent to which intact performance on the MoCA reflects intact cognition as determined by neuropsychological assessment. Methods In this retrospective study, cognitive profiles for 136 acute stroke patients admitted to the Acute Stroke Unit who had available MoCA and neuropsychological assessment data were examined. Results 22% of our patients were deemed cognitively intact on the MoCA. Of …
Increase in transmitted resistance to non-nucleoside reverse transcriptase inhibitors among newly diagnosed HIV-1 infections in Europe
2014
Background: One out of ten newly diagnosed patients in Europe was infected with a virus carrying a drug resistant mutation. We analysed the patterns over time for transmitted drug resistance mutations (TDRM) using data from the European Spread program.Methods: Clinical, epidemiological and virological data from 4317 patients newly diagnosed with HIV-1 infection between 2002 and 2007 were analysed. Patients were enrolled using a pre-defined sampling strategy.Results: The overall prevalence of TDRM in this period was 8.9% (95% CI: 8.1-9.8). Interestingly, significant changes over time in TDRM caused by the different drug classes were found. Whereas nucleoside resistance mutations remained con…
Optimised versus standard dosing of vancomycin in infants with Gram-positive sepsis (NeoVanc): a multicentre, randomised, open-label, phase 2b, non-i…
2022
Summary Background Vancomycin is the most widely used antibiotic for neonatal Gram-positive sepsis, but clinical outcome data of dosing strategies are scarce. The NeoVanc programme comprised extensive preclinical studies to inform a randomised controlled trial to assess optimised vancomycin dosing. We compared the efficacy of an optimised regimen to a standard regimen in infants with late onset sepsis that was known or suspected to be caused by Gram-positive microorganisms. Methods NeoVanc was an open-label, multicentre, phase 2b, parallel-group, randomised, non-inferiority trial comparing the efficacy and toxicity of an optimised regimen of vancomycin to a standard regimen in infants aged …
Borrelia burgdorferi sensu lato and Anaplasma phagocytophilum in Ixodes ricinus ticks in Brønnøysund in northern Norway
2013
Ticks are important vectors of disease for both humans and animals. In Europe, Lyme borreliosis is the most abundant tick-borne human disease, whereas anaplasmosis, or tick-borne fever, is the most widespread tick-borne infection in domestic animals. However, knowledge about the prevalence of the causative disease agents in questing ticks in the northern range of their distribution in Norway is missing. Ixodes ricinus ticks were therefore collected by flagging vegetation in Brønnøysund, an area near the Arctic Circle in Norway where ticks have been abundant for decades. Ticks were analysed for infection with Borrelia burgdorferi sensu lato and Anaplasma phagocytophilum by real-time PCR ampl…
Host dispersal shapes the population structure of a tick-borne bacterial pathogen
2020
Birds are hosts for several zoonotic pathogens. Because of their high mobility, especially of longdistance migrants, birds can disperse these pathogens, affecting their distribution and phylogeography. We focused on Borrelia burgdorferi sensu lato, which includes the causative agents of Lyme borreliosis, as an example for tick-borne pathogens, to address the role of birds as propagation hosts of zoonotic agents at a large geographical scale. We collected ticks from passerine birds in 11 European countries. B. burgdorferi s.l. prevalence in Ixodes spp. was 37% and increased with latitude. The fieldfare Turdus pilaris and the blackbird T. merula carried ticks with the highest Borrelia prevale…