Search results for "GENETICS"

showing 10 items of 12494 documents

Antagonistic effects of a Mhc class I allele on malaria-infected house sparrows.

2008

8 pages; International audience; Genes of the Major Histocompatibility Complex (Mhc) play a fundamental role during the immune response because MHC molecules expressed on cell surface allow the recognition and presentation of antigenic peptides to T-lymphocytes. Although Mhc alleles have been found to correlate with pathogen resistance in several host-parasite systems, several studies have also reported associations between Mhc alleles and an accrued infection risk or an accelerated disease progression. The existence of these susceptibility alleles is puzzling, as the cost generated by the infection should rapidly eliminate them from the population. Here, we show that susceptibility alleles…

0106 biological sciencesPlasmodiumMESH : Molecular Sequence DataMESH : DNAGenes MHC Class IMESH: Amino Acid Sequenceco-evolutionMESH: Base SequenceMESH : Microsatellite Repeats01 natural sciencessusceptibilityMESH: SparrowsPleiotropy[ SDV.EE.IEO ] Life Sciences [q-bio]/Ecology environment/SymbiosisMESH: AnimalsMESH : Malaria AvianGenetics0303 health scienceseducation.field_of_studybiologyMESH : Amino Acid Sequence[SDV.BID.EVO]Life Sciences [q-bio]/Biodiversity/Populations and Evolution [q-bio.PE]MESH: DNAMESH: Genetic Predisposition to DiseaseMESH: Genes MHC Class I3. Good healthMESH: Malaria Avian[ SDV.BID.EVO ] Life Sciences [q-bio]/Biodiversity/Populations and Evolution [q-bio.PE]MESH: Haemosporidaavian malariaSparrows[ SDV.MP.PAR ] Life Sciences [q-bio]/Microbiology and Parasitology/ParasitologyMalaria AvianMolecular Sequence DataPopulationMESH: Genetics PopulationMajor histocompatibility complex010603 evolutionary biologyMESH : Genes MHC Class Iresistance03 medical and health sciencesImmune systemAvian malariaMHC class ImedicinePasser domesticusAnimalsGenetic Predisposition to Disease[SDV.MP.PAR]Life Sciences [q-bio]/Microbiology and Parasitology/ParasitologyAmino Acid SequenceAlleleeducationAllelesEcology Evolution Behavior and Systematics030304 developmental biologyparasite competitionMESH: Molecular Sequence DataBase Sequencehouse sparrowMESH: PlasmodiumMESH: Alleles[ SDV.GEN.GA ] Life Sciences [q-bio]/Genetics/Animal geneticsDNAHaemosporidamedicine.diseaseMESH : Genetics PopulationHistocompatibility[SDV.GEN.GA]Life Sciences [q-bio]/Genetics/Animal geneticsGenetics PopulationMESH : PlasmodiumImmunologybiology.proteinMESH : Base SequenceMESH : Genetic Predisposition to DiseaseAntagonistic pleiotropyMESH : SparrowsMESH : AnimalsMESH : HaemosporidaMESH: Microsatellite RepeatsMESH : AllelesMicrosatellite Repeats[SDV.EE.IEO]Life Sciences [q-bio]/Ecology environment/Symbiosis
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Sensitive measure of prevalence and parasitaemia of haemosporidia from European blackbird (Turdus merula) populations: value of PCR-RFLP and quantita…

2006

8 pages; International audience; Haemosporidian parasites are common in birds in which they act as an important selective pressure. While most studies so far have focused on the effect of their prevalence on host life-history traits, no study has measured the effect of parasitaemia. We developed molecular methods to detect, identify and quantify haemosporidia in 2 natural populations of the Blackbird Turdus merula. Three different parasite genotypes were found - 1 Haemoproteus and 2 Plasmodium. A PCR-RFLP screening revealed that only approximately 3% of blackbirds were free of parasites, compared to the 34% of uninfected birds estimated by blood smear screening. A quantitative PCR (q-PCR) a…

0106 biological sciencesPlasmodiumMESH: ParasitemiaMESH: Protozoan Infections AnimalMESH : Protozoan Infections AnimalMESH : PrevalenceMESH : Bird DiseasesMESH : ParasitemiaParasitemia01 natural sciencesPlasmodiumPolymerase Chain ReactionMESH: Bird Diseases030308 mycology & parasitologylaw.inventionPCR-RFLPlawGenotype[ SDV.EE.IEO ] Life Sciences [q-bio]/Ecology environment/SymbiosisParasite hostingMESH: AnimalsPasseriformesProtozoan Infections AnimalMESH : Polymerase Chain ReactionPolymerase chain reactionGenetics0303 health sciencesbiologyInfectious DiseasesMESH: HaemosporidaMESH : Sensitivity and SpecificityPolymorphism Restriction Fragment Length[ SDV.MP.PAR ] Life Sciences [q-bio]/Microbiology and Parasitology/Parasitologyfield populationsprevalenceZoology010603 evolutionary biologySensitivity and SpecificityparasitaemiaApicomplexa03 medical and health sciencesparasitic diseasesAnimalsTurdus merula[SDV.MP.PAR]Life Sciences [q-bio]/Microbiology and Parasitology/ParasitologyMESH: PrevalenceMESH : Polymorphism Restriction Fragment Length[SDV.GEN]Life Sciences [q-bio]/GeneticsHost (biology)Bird DiseasesMESH: PlasmodiumMESH: Polymorphism Restriction Fragment LengthMESH: PasseriformesMESH: Polymerase Chain Reactionbiology.organism_classificationHaemosporidaMESH : PasseriformesMESH: Sensitivity and SpecificityMESH : PlasmodiumHaemoproteusVector (epidemiology)Animal Science and ZoologyParasitologyHaemoproteusMESH : AnimalsMESH : Haemosporida[ SDV.GEN ] Life Sciences [q-bio]/Geneticsreal-time PCR[SDV.EE.IEO]Life Sciences [q-bio]/Ecology environment/Symbiosis
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Plasmodium relictum infection and MHC diversity in the house sparrow (Passer domesticus).

2010

Antagonistic coevolution between hosts and parasites has been proposed as a mechanism maintaining genetic diversity in both host and parasite populations. In particular, the high level of genetic diversity usually observed at the major histocompatibility complex (MHC) is generally thought to be maintained by parasite-driven selection. Among the possible ways through which parasites can maintain MHC diversity, diversifying selection has received relatively less attention. This hypothesis is based on the idea that parasites exert spatially variable selection pressures because of heterogeneity in parasite genetic structure, abundance or virulence. Variable selection pressures should select for…

0106 biological sciencesPlasmodium[ SDV.IMM.IA ] Life Sciences [q-bio]/Immunology/Adaptive immunology01 natural sciencessusceptibilityMajor Histocompatibility Complex[ SDE ] Environmental SciencesGene Frequency[ SDV.EE.IEO ] Life Sciences [q-bio]/Ecology environment/SymbiosisResearch ArticlesGeneral Environmental ScienceGenetics0303 health sciencesbiologyPlasmodium relictumGeneral Medicine3. Good health[SDV.IMM.IA]Life Sciences [q-bio]/Immunology/Adaptive immunologyGenetic structure[SDE]Environmental Sciencesavian malariaGeneral Agricultural and Biological SciencesSparrowsMalaria AvianAntagonistic CoevolutionMajor histocompatibility complex010603 evolutionary biologyGeneral Biochemistry Genetics and Molecular Biologyresistance03 medical and health sciencesAvian malariamedicinePasser domesticusAnimalsSelection GeneticAllelesSelection (genetic algorithm)030304 developmental biologyLocal adaptationGenetic diversity[ SDE.BE ] Environmental Sciences/Biodiversity and EcologyGeneral Immunology and Microbiologydiversifying selectionbiology.organism_classificationmedicine.diseaseImmunity InnatePlasmodium relictumbiology.protein[SDE.BE]Environmental Sciences/Biodiversity and Ecology[SDV.EE.IEO]Life Sciences [q-bio]/Ecology environment/Symbiosis
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Distinct protoconchs recognised in three of the larger Mediterranean Cerithium species (Caenogastropoda: Cerithiidae)

2017

The gastropod genus Cerithium includes several polymorphic species which are hardly distinguishable using a morphological approach based on teleoconch characters. Here we show that protoconch characters can be reliably used to identify the larger Mediterranean species (Cerithium alucastrum, C. repandum and C. vulgatum), and to assess their intraspecific variability. Based on a large amount of morphological data, we show that a multispiral, strongly sculptured protoconch (traditionally associated with C. vulgatum) is found in C. alucastrum. This species originated in the Pliocene. A multispiral, weakly sculptured protoconch, not observed previously, is reported for C. vulgatum. A paucispiral…

0106 biological sciencesPlioceneCerithiumBiogeographyGastropodaZoology010502 geochemistry & geophysics010603 evolutionary biology01 natural scienceslarval developmenttaxonomyGastropodaAnthropoceneGeneticsEcology Evolution Behavior and Systematicsbiogeography0105 earth and related environmental sciencesCaenogastropodabiologyEcologyCerithiidaebiology.organism_classificationPleistoceneProtoconchAnimal Science and ZoologyTaxonomy (biology)Type localityecophenotype
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Detection of Allee effects in marine fishes: analytical biases generated by data availability and model selection

2017

The demographic Allee effect, or depensation, implies positive association between per capita population growth rate and population size at low abundances, thereby lowering growth ability of sparse populations. This can have far-reaching consequences on population recovery ability and colonization success. In the context of marine fishes, there is a widespread perception that Allee effects are rare or non-existent. However, studies that have failed to detect Allee effects in marine fishes have suffered from several fundamental methodological and data limitations. In the present study, we challenge the prevailing perception about the rarity of Allee effects by analysing nine populations of …

0106 biological sciencesPopulation DynamicsAtlantic herringBiologyModels Biological010603 evolutionary biology01 natural sciencesPopulation densityGeneral Biochemistry Genetics and Molecular BiologycompensationDepensationsymbols.namesakePer capitaAnimalsPopulation growth14. Life underwaterClupea harengusPopulation GrowthGeneral Environmental ScienceAllee effectlow-abundance dynamicsPopulation DensityModels StatisticalEcologyGeneral Immunology and MicrobiologyEcology010604 marine biology & hydrobiologyModel selectionPopulation sizestock–recruitment relationshipFishesBayes TheoremGeneral MedicineData availabilitydepensationsymbolsta1181General Agricultural and Biological SciencesProceedings of the Royal Society B: Biological Sciences
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Assessing the nucleotide diversity of three aphid species by RAPD

1997

A method is presented for the estimation of nucleotide diversity and genetic structure of populations from RAPD (random amplified polymorphic DNA) data. It involves a modification of the technique developed by Lynch and Crease (1990) for the case of restriction sites as survey data. As new elements the method incorporates (i) dominance correction, (ii) values of asexual reproduction of the populations sampled, and (iii) an analytical variance of the number of nucleotide substitutions per site. Sampling was carried out at two geographic scales for three aphid species. At a macrogeographic scale, populations of Rhopalosiphum padi did not show statistical genetic differentiation. Aphis gossypi…

0106 biological sciencesPopulation010603 evolutionary biology01 natural sciencesNucleotide diversity03 medical and health sciencesRhopalosiphum padiRAPD[SDV.BID.EVO] Life Sciences [q-bio]/Biodiversity/Populations and Evolution [q-bio.PE]educationEcology Evolution Behavior and SystematicsComputingMilieux_MISCELLANEOUS030304 developmental biologyGenetics0303 health scienceseducation.field_of_studyGenetic diversityAphidbiology[SDV.BID.EVO]Life Sciences [q-bio]/Biodiversity/Populations and Evolution [q-bio.PE]biology.organism_classificationGENETIQUE MITOCHONDRIALERAPD010602 entomologyINSECTEGenetic structureMyzus persicae
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Town population size and structuring into villages and households drive infectious disease risks in pre-healthcare Finland

2021

Social life is often considered to cost in terms of increased parasite or pathogen risk. However, evidence for this in the wild remains equivocal, possibly because populations and social groups are often structured, which affects the local transmission and extinction of diseases. We test how the structuring of towns into villages and households influenced the risk of dying from three easily diagnosable infectious diseases—smallpox, pertussis and measles—using a novel dataset covering almost all of Finland in the pre-healthcare era (1800–1850). Consistent with previous results, the risk of dying from all three diseases increased with the local population size. However, the division of towns …

0106 biological sciencesPopulationDiseaseCommunicable Diseases010603 evolutionary biology01 natural sciencesMeaslesGeneral Biochemistry Genetics and Molecular BiologySocial group03 medical and health sciencesmedicineHumansSmallpoxCitieseducationFinland030304 developmental biologyGeneral Environmental SciencePopulation Density0303 health scienceseducation.field_of_studyEcologyGeneral Immunology and MicrobiologyTransmission (medicine)Population sizeGeneral Medicinemedicine.diseaseGeographyInfectious disease (medical specialty)General Agricultural and Biological SciencesDelivery of Health CareDemographyProceedings of the Royal Society B: Biological Sciences
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Isozyme analysis of genetic diversity in wild Sicilian populations of Brassica sect. Brassica in view of genetic resources management

2004

In Sicily and in the small surrounding islands the section Brassica of the genus Brassica comprises five species, B. insularis Moris, B. incana Ten., B. macrocarpa Guss., B. rupestris Raf. and B. villosa Biv. These taxa represent a genetic resource as relatives of kale crops but some populations are endangered or threatened, thus isozyme analyses were performed to assess the genetic diversity degree at population and species levels in order to assist the design of conservation management programs. Eleven loci from five enzyme systems (aconitase, leucine aminopeptidase, 6-phosphogluconate dehydrogenase, phosphoglucoisomerase phosphoglucomutase) were analyzed in sixteen natural population (fi…

0106 biological sciencesPopulationEndangered speciesBrassicaPlant ScienceBiology010603 evolutionary biology01 natural sciencesBrassica sect. Brassica wild sicilian populations Genetic resources Genetic structure Isozyme diversitySettore BIO/01 - Botanica GeneraleGenusBotanyGeneticseducationEcology Evolution Behavior and Systematicseducation.field_of_studyGenetic diversity[SDV.GEN]Life Sciences [q-bio]/GeneticsVillosaSettore BIO/02 - Botanica SistematicaAMELIORATION DES PLANTES15. Life on landbiology.organism_classificationGenetic structureThreatened speciesAgronomy and Crop Science010606 plant biology & botany
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Genetic analysis of organoleptic quality in fresh market tomato. 1. Mapping QTLs for physical and chemical traits

2001

Improving organoleptic quality is an important but complex goal for fresh market tomato breeders. A total of 26 traits involved in organoleptic quality variation were evaluated, in order to understand the genetic control of this characteristic. A recombinant inbred line (RIL) population was developed from an intraspecific cross between a cherry tomato line with a good overall aroma intensity and an inbred line with a common taste but with bigger fruits. Physical traits included fruit weight, diameter, color (L,a,b), firmness and elasticity. Chemical traits were dry matter weight, titratable acidity, pH, and the contents of soluble solids, sugars, lycopene, carotene and 12 aroma volatiles. R…

0106 biological sciencesPopulationOrganoleptic[SDV.GEN] Life Sciences [q-bio]/GeneticsQuantitative trait locus01 natural sciencesLycopersicon03 medical and health scienceschemistry.chemical_compoundCherry tomatoBotanyGeneticsDry mattereducationAromaComputingMilieux_MISCELLANEOUS030304 developmental biology2. Zero hunger0303 health scienceseducation.field_of_study[SDV.GEN]Life Sciences [q-bio]/Geneticsbiologyfood and beveragesGeneral Medicinebiology.organism_classificationLycopeneHorticulturechemistryAgronomy and Crop Science010606 plant biology & botanyBiotechnology
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Genetic structure of a European forest species, the edible dormouse ( Glis glis ): a consequence of past anthropogenic forest fragmentation?

2019

International audience; The genetic structure of forest animal species may allow the spatial dynamics of the forests themselves to be tracked. Two scales of change are commonly discussed: changes in forest distribution during the Quaternary, due to glacial/interglacial cycles, and current fragmentation related to habitat destruction. However, anthropogenic changes in forest distribution may have started well before the Quaternary, causing fragmentation at an intermediate time scale that is seldom considered. To explore the relative role of these processes, the genetic structure of a forest species with narrow ecological preferences, the edible dormouse (Glis glis), was investigated in a set…

0106 biological sciencesPopulationSettore BIO/05 - ZoologiaClimate changeearly anthropogenic deforestationBiologyphylogeography010603 evolutionary biology01 natural sciences03 medical and health sciencesDeforestationABC analysisGlacial periodeducationGliridaeEcology Evolution Behavior and Systematicsglobal change030304 developmental biologyEdible dormouse0303 health scienceseducation.field_of_studyforest fragmentation[SDV.GEN.GPO]Life Sciences [q-bio]/Genetics/Populations and Evolution [q-bio.PE]Ecology[SDV.BID.EVO]Life Sciences [q-bio]/Biodiversity/Populations and Evolution [q-bio.PE]Fragmentation (computing)15. Life on landbiology.organism_classificationABC analysiHabitat destructionGenetic structure
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