Search results for "GENI"

PARENTAL PERCEPTION OF CHILDHOOD OBESITY IN AN INNER-CITY AREA OF PALERMO, ITALY

2008

Introduction: The prevalence of overweight and obesity in Sicilian schoolchildren is one of the highest ever reported: indeed, prevalence of overweight and obesity appears to be nearly 40% at age 11 and over 25% at age 15. Excessive weight during childhood stems fromseveral interacting factors, including poor diet and exercise habits. The objective of this study was to evaluate in a sample of parents living in an inner-city area of Palermo, Italy, the perception of weight excess as a problem in childhood and the awareness about the role of physical activity, beliefs about contributors and parties having responsibility in counteracting the obesity crisis. Methods: A cross-sectional survey wa…

Increased dosage of Ink4/Arf protects against glucose intolerance and insulin resistance associated with aging

2013

Recent genome-wide association studies have linked type-2 diabetes mellitus to a genomic region in chromosome 9p21 near the Ink4/Arf locus, which encodes tumor suppressors that are up-regulated in a variety of mammalian organs during aging. However, it is unclear whether the susceptibility to type-2 diabetes is associated with altered expression of the Ink4/Arf locus. In the present study, we investigated the role of Ink4/Arf in age-dependent alterations of insulin and glucose homeostasis using Super-Ink4/Arf mice which bear an extra copy of the entire Ink4/Arf locus. We find that, in contrast to age-matched wild-type controls, Super-Ink4/Arf mice do not develop glucose intolerance with agi…

Activation of the p38MAPK cascade is associated with upregulation of TNF alpha receptors in the spinal motor neurons of mouse models of familial ALS.

2005

Phosphorylated p38 mitogen-activated protein kinase (p38MAPK), but not activated c-jun-N-terminal kinase (JNK), increases in the motor neurons of transgenic mice overexpressing ALS-linked SOD1 mutants at different stages of the disease. This effect is associated with a selective increase of phosphorylated MKK3-6, MKK4 and ASK1 and a concomitant upregulation of the TNFalpha receptors (TNFR1 and TNFR2), but not IL1beta and Fas receptors. Activation of both p38 MAPK and JNK occurs in the activated microglial cells of SOD1 mutant mice at the advanced stage of the disease; however, this effect is not accompanied by the concomitant activation of the upstream kinases ASK1 and MKK3,4,6, while both …

Expression of p63, p53 and ki-67 in patients with cervical intraepithelial neoplasia

2017

Objective: Cervical intraepithelial neoplasia (CIN) is a dysplastic process in cervical squamous epithelium and carries a risk of progression to cervical cancer. The aim of this study was to compare expression of three biomarkers named p53, p63 and Ki-67 in patients with various grades of cervical intraepithelial neoplasia and in a control group. Material and Method: 58 patients were enrolled in the study. Each patient underwent a colposcopy-guided biopsy of the cervix. Immunostaining for markers (p53, p63 and Ki-67) was performed on tissue samples of normal cases (n=10), CIN I (n=20), CIN II (n=14), and CIN III (n=14). Results: Our study showed a significant increase of the expression of t…

p73 deficiency results in impaired self renewal and premature neuronal differentiation of mouse neural progenitors independently of p53

2010

10 p.-5 fig.

Tumor odontogenico adenomatoide folicular: Estudio inmunohistoquimico

2006

El tumor odontogénico adenomatoide (TOA) es una infrecuente lesión odontogénica benigna, que aparece en pacientes jóvenes, generalmente mujeres en la segunda década de la vida, a menudo como una lesión radiolúcida de aspecto quístico unilocular, en asociación a un diente, usualmente canino, no erupcionado. A pesar de haberse denominado también adenoameloblastoma o tumor ameloblástico adenomatoide, el TOA es una lesión benigna con una muy baja tendencia a la recidiva, mostrando una morfología muy peculiar (apariencia basaloide con estructuras glanduliformes, calcificaciones esferulares, presencia de material amiloide) que facilitan su reconocimiento histológico. Se presenta un análisis clíni…

Il "carattere essenziale" del paesaggio come Patrimonio. Sei progetti per il territorio dei Monti Erei

2019

Il paesaggio italiano è un Patrimonio incommensurabile che va conservato e tramandato. Nel paesaggio si raccoglie la sintesi delle stratificazioni, della storia e della cultura del nostro territorio. Il paesaggio è ciò che percepiamo esteticamente, ma anche ciò che creiamo e modifichiamo eticamente. Al progetto contemporaneo spetta il nobile compito di riconoscere il carattere essenziale del paesaggio per poterlo rinnovare – attualizzandolo al presente – e consegnare alle generazioni future. La cultura architettonica contemporanea non si è sempre rivelata all’altezza di questo compito. Alla cura e alla trasformazione attenta del paesaggio si è spesso opposta una speculazione edilizia, che h…

Microrganismi fungini associati a Rincophorus ferrugineus (Olivr) in Sicilia e valutazione dell'efficacia entomopatogena di un ceppo di Beauveria bas…

2009

congenital true cystic mass of the pancreas in a Young woman: which treatment?

2013

Aim. We report a case of congenital true pancreatic cyst with high level of enzymatic activity, rarely seen in young and children which, to the best of our knowledge, rarely has previously been reported. A young girl was admitted to our clinic with a history of abdominal swelling and pain during exercise for many months. A mobile, smooth, non-tender mass was palpated on the left side of the abdomen during physical examination. Ultrasonography and computed tomography imaging revealed a not subdivide cystic mass sized 11.51x8.2 cm. Methods. Surgical treatment was considered, but given the young age of the patient, we declined for fear of complications. Therefore, US-guided percutaneous draina…

La genitorialità nella coppia omoaffettiva

2020

Il saggio affronta il delicato tema della aspirazione alla genitorialità procreativa da parte delle coppie omoaffettive nel nostro ordinamento alla luce dei divieti legislativi e del diritto vivente, considerati nel quadro dei principi costituzionali di riferimento. Indica argomenti e possibili soluzioni ermeneutiche per affermare un diritto alla genitorialità e per offrire adeguata copertura giuridica alla posizione del nato. The essay deals with the delicate issue of the aspiration to procreative parenthood by homosexual couples in our legal system in the light of the relevant legislative prohibitions and the recent case-law, considered within the framework of the constitutional principle…