Search results for "GENI"
showing 10 items of 6843 documents
Estimates of the modeling error generated by homogenization of an elliptic boundary value problem
2016
Erworben im Rahmen der Schweizer Nationallizenzen (http://www.nationallizenzen.ch)
L'ESAME CAPILLAROSCOPICO ORALE: NUOVA METODICA DIAGNOSTICA
2005
The morphological-functional study of microcirculation is of fundamental importance; in fact, the microvascular bed is directly involved both in autoimmune etiopathogenesis pathologies, and in acute and chronic inflammatory etiopathogenesis pathologies. Oral capillaroscopy is a very stimulating method for studying microcirculation, because of the possibility of studying small vessels in vivo by means of a microscope. Today, it is becoming more reliable thanks to the improvement of the observation tools (photography, videomicroscopy).
DEVELOPMENT & QUALIFICATION OF BIOASSAYS FOR THE DETERMINATION OF THE BIOACTIVITY, PREDICTIVE PHARMACOKINETICS AND POTENTIAL IMMUNOGENICITY OF THERAP…
2021
The critical quality attributes of a given biotherapeutic monoclonal antibody (mAb), its molecular characterization, functional assessment and effector function analysis should be defined and profiled in detail during the life cycle of a biotherapeutic drug. In the past, this product characterization was simple and standardized. In today’s complex world of biologics, success demands a more thoughtful approach and drug developers are investing in advanced analytics much earlier in the development process. Indeed, investing in selected sophisticated and state of the art analytics in early developmental phases of a therapeutic monoclonal antibody may mitigate risks by confirming that the drug …
Follow-up post natale in nati da madre con infezione certa da Toxoplasma gondii considerazioni sul management prenatale.
2005
The clinical management of perinatal toxoplasmosis involves a gynaecologist during pregnancy and a neonatologist after delivery. Then, in the absence of a uniform approach, early evaluation of infected infants requires a thorough long-term follow-up also in asymptomatic children, who have to be observed for at least one year due to unpredictable sequelae in later life. We retrospectively analyzed pregnancy management of 54 women with certain infection from Toxoplasma gondii (TG) and prospectively enrolled their infants to compare prenatal management with postnatal clinical outcome. All mothers with seroconversion for TG infection were from the Palermo area and were retrospectively analyzed,…
Desarrollo de material multimedia para la prevención de riesgos en el laboratorio docente de Química Analítica. Segunda parte: Laboratorio de Instrum…
2010
El material consta de un video y un cuestionario. El video contiene información básica sobre la prevención y riesgos que conlleva la utilización y manejo de instrumentación en los laboratorios de Química Analítica. Se abordan los aspectos generales sobre el trabajo seguro en un laboratorio de instrumentación analítica, así como los riesgos específicos de las principales técnicas analíticas: espectroscopia molecular, espectroscopia atómica, métodos eléctricos y métodos cromatográficos. Finalmente, el cuestionario contiene diversas preguntas relacionadas con las conductas de trabajo adecuadas para la prevención de riesgos en el laboratorio de instrumentación analítica. El material consta d'un…
Verde e allergie
2016
La qualità dell’ambiente urbano è sempre più oggetto di attenzione sia da parte degli amministratori che dei cittadini. Il verde, inteso come l’insieme delle diverse tipologie di impianti presenti nelle città, costituisce un fondamentale elemento per misurare la qualità dell’ambiente urbano. Le sue modificazioni storiche, la sua progettazione e manutenzione assumono rilievo importante soprattutto se si considera la presenza di specie allergeniche che possono condizionare la vita di un’importante fetta della popolazione presente. Tra le diverse soluzioni praticabili per ridurre l’esposizione dei pazienti allergici al polline iniziano a diffondersi anche le moderne tecnologie, come app dedica…
Periodontitis and alzheimer´s disease
2020
Background Alzheimer's disease (AD), the main cause of dementia in the adult population, is characterized by a progressive loss of cognitive function. It is considered that neuroinflammation plays a fundamental role in its onset and progression. The bacteria present in the disbiotic microbiome generated during the course of periodontitis (PE) are capable of inducing a systemic inflammatory response, exacerbating the production of proinflammatory mediators that have the potential to spread to the systemic circulation. Material and Methods A literature review was made using the databases Scielo, PubMed, EBSCO and key words "Alzheimer disease", "Periodontitis", "Neurodegeneration", "Inflammati…
Challenges Associated with Byproducts Valorization—Comparison Study of Safety Parameters of Ultrasonicated and Fermented Plant-Based Byproducts
2020
In order to promote the efficient use of byproducts from the production of plant-based beverages, which still contain a large amount of nutritional and functional compounds, microbiological and chemical safety characteristics should be evaluated and, if needed, improved. Many challenges are associated with byproducts valorization, and the most important ones, which should be taken into account at the further steps of valorization, are biological and chemical safety. For safety improving, several technological treatments (biological, physical etc.) can be used. In this study, the influence of low-frequency ultrasonication (US) and fermentation with Lactobacillus casei LUHS210 strain, as phys…
Estudio y optimización de nuevos catalizadores para la producción selectiva de olefinas ligeras
2017
El cambio climático ha sido calificado como el mayor de los problemas a los que se enfrenta la humanidad actualmente. Sus consecuencias pueden ser extremas y pueden poner en peligro a todas las especies que habitan este planeta. La solución implica necesariamente un esfuerzo global, tanto a nivel político como científico. Afortunadamente, los químicos e ingenieros químicos tienen a su alcance poderosas herramientas con las que contribuir, incluyendo la química sostenible y, en particular, la catálisis. La catálisis permite hacer un uso más eficiente de los recursos que requieren de una transformación química. Los recursos fósiles son la principal reserva de carbono al alcance del ser humano…
Prostaglandin E2 and prostaglandin F2 alpha as endometrial receptivity biomarkers in successful embryo implantation
2014
Failure in the adhesion of the human blastocyst to the endometrium has been described as an important cause of infertility. Establishing the period of the so-called window of implantation and understanding the molecular mechanisms associated with embryo implantation has clinical and scientific implications. While over the last decades histological evaluation has been used to determine the phase of the menstrual cycle of the endometrium, the poor information obtained has made the case of using new technologies to identify specific markers, understand and characterize the receptive stage. This doctoral thesis investigates the existence, function and clinical impact of two specific lipids, the…